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- W3037333076 abstract "TYPE: Abstract Publication TOPIC: Signs and Symptoms of Chest Diseases PURPOSE: Sarcoidosis often presents with nonspecific symptoms which make diagnosis difficult at times. As sarcoidosis has been associated with immunodeficiency disorders and malignancies it is necessary to pursue the necessary workup to rule these conditions out. Here we discuss a most unusual presentation of sarcoidosis. METHODS: CBC, CMP, Chest Xray, CT Chest RESULTS: A 38-year-old male presented with abdominal pain with associated nausea, vomiting, and 25 lb weight loss in a 2-week period. CT Abdomen showed incidental hepatosplenomegaly. Labwork showed patient had AKI (Cr ∼2.0) and hypercalcemia (Ca 13.3) with suppressed intact PTH suggestive of possible malignancy. CT chest revealed cystic lung disease predominantly in upper lobes with ground glass opacities. Oddly, patient has no pulmonary symptoms and had negative workup for immunodeficiency disorders, autoimmune diseases, and malignancy. Patient underwent bronchoscopy with biopsy samples taken showing granulomas consistent with diagnosis of sarcoidosis. Patient was started on steroid therapy after which he clinically improved. CONCLUSIONS: Sarcoidosis is an inflammatory disease which predominantly affects the lungs and lymph glands. Tissue biopsy shows noncaseating granulomas. Patient’s presentation was most unusual due to his Caucasian race and lack of respiratory symptoms. Moreover, imaging showed cystic lung disease which was unusual presentation for sarcoidosis especially in the early stages since fibrocystic changes are usually seen in advanced stages of sarcoidosis. CLINICAL IMPLICATIONS: Sarcoidosis is a diagnosis of exclusion and due to the vast heterogeneity of presentation the disease can be a difficult one to diagnose. Therefore,clinicians should always be open minded to include Sarcoidosis in their differential diagnoses during workup of pulmonary diseases. DISCLOSURE: No significant relationships. KEYWORD: sarcoidosis" @default.
- W3037333076 created "2020-07-02" @default.
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- W3037333076 date "2020-06-01" @default.
- W3037333076 modified "2023-09-26" @default.
- W3037333076 title "A RARE CARE OF SARCOIDOSIS WITH AN UNFAMILIAR PRESENTATION" @default.
- W3037333076 doi "https://doi.org/10.1016/j.chest.2020.05.476" @default.
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