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- W3037339940 abstract "The proto-oncogene c- Myc plays a crucial role in the growth and division of many animal cells. Previous studies have identified an active upregulation of c-Myc by Toxoplasma tachyzoites, suggesting the existence of one or more exported “effector” proteins. The identity of such an effector, however, has not previously been known. Here, we show that a previously known secreted protein, GRA16, plays a crucial role in c-Myc upregulation. This finding will enable further dissection of the precise mechanism and role of c-Myc upregulation in Toxoplasma -infected cells." @default.
- W3037339940 created "2020-07-02" @default.
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- W3037339940 date "2020-06-24" @default.
- W3037339940 modified "2023-10-11" @default.
- W3037339940 title "<i>Toxoplasma</i> Uses GRA16 To Upregulate Host c-Myc" @default.
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- W3037339940 doi "https://doi.org/10.1128/msphere.00402-20" @default.
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