FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037542376> ?p ?o ?g. }

• W3037542376 abstract "Abstract Background: Treatment plans for Parkinson’s disease (PD) are based on a disease stage scale, which is generally determined using a manual, observational procedure. Automated, sensor-based discrimination saves labor and costs in clinical settings and may offer augmented stage determination accuracy. Previous automated devices were either cumbersome or costly and were not suitable for individuals who cannot walk without support. Methods: Since 2017, a device has been available that successfully detects PD and operates for people who cannot walk without support. In the present study, the suitability of this device for automated discrimination of PD stages was tested. The device consists of a walking frame fitted with sensors to simultaneously support walking and monitor patient gait. Sixty-five PD patients in Hoehn and Yahr (HY) stages 1 to 4 and 24 healthy controls were subjected to supported Timed Up and Go (TUG) tests, while using the walking frame. The walking trajectory, velocity, acceleration and force were recorded by the device throughout the tests. These physical parameters were converted into symptomatic spatiotemporal quantities that are conventionally used in PD gait assessment. Results: An analysis of variance (ANOVA) test extended by a confidence interval (CI) analysis indicated statistically significant separability between HY stages for the following spatiotemporal quantities: TUG time (p < 0.001), straight line walking time (p < 0.001), turning time (p < 0.001), and step count (p < 0.001). A negative correlation was obtained for mean step velocity (p < 0.001) and mean step length (p < 0.001). Moreover, correlations were established between these, as well as additional spatiotemporal quantities, and disease duration, L-dihydroxyphenylalanine-(L-DOPA) dose, motor fluctuation, dyskinesia and the mobile part of the Unified Parkinson Disease Rating Scale (UPDRS). Conclusions: We have proven that stage discrimination of PD can be automated, even to patients who cannot support themselves. A similar method might be successfully applied to other gait disorders." @default.
• W3037542376 created "2020-07-02" @default.
• W3037542376 creator A5009054780 @default.
• W3037542376 creator A5024089495 @default.
• W3037542376 creator A5025584866 @default.
• W3037542376 creator A5034845140 @default.
• W3037542376 creator A5067213867 @default.
• W3037542376 creator A5087231010 @default.
• W3037542376 date "2020-09-24" @default.
• W3037542376 modified "2023-09-26" @default.
• W3037542376 title "Automated Stage Discrimination of Parkinson’s Disease" @default.
• W3037542376 cites W1070793310 @default.
• W3037542376 cites W1760076767 @default.
• W3037542376 cites W1837130411 @default.
• W3037542376 cites W1966165134 @default.
• W3037542376 cites W1974704788 @default.
• W3037542376 cites W1999702935 @default.
• W3037542376 cites W2034825135 @default.
• W3037542376 cites W2075188042 @default.
• W3037542376 cites W2100663250 @default.
• W3037542376 cites W2105382574 @default.
• W3037542376 cites W2126008330 @default.
• W3037542376 cites W2144954419 @default.
• W3037542376 cites W2147331821 @default.
• W3037542376 cites W2149549442 @default.
• W3037542376 cites W2162908184 @default.
• W3037542376 cites W2170504226 @default.
• W3037542376 cites W2172487091 @default.
• W3037542376 cites W2294748375 @default.
• W3037542376 cites W2317190231 @default.
• W3037542376 cites W2567537979 @default.
• W3037542376 cites W2606165363 @default.
• W3037542376 cites W2789525912 @default.
• W3037542376 doi "https://doi.org/10.15212/bioi-2020-0006" @default.
• W3037542376 hasPublicationYear "2020" @default.
• W3037542376 type Work @default.
• W3037542376 sameAs 3037542376 @default.
• W3037542376 citedByCount "2" @default.
• W3037542376 countsByYear W30375423762021 @default.
• W3037542376 crossrefType "journal-article" @default.
• W3037542376 hasAuthorship W3037542376A5009054780 @default.
• W3037542376 hasAuthorship W3037542376A5024089495 @default.
• W3037542376 hasAuthorship W3037542376A5025584866 @default.
• W3037542376 hasAuthorship W3037542376A5034845140 @default.
• W3037542376 hasAuthorship W3037542376A5067213867 @default.
• W3037542376 hasAuthorship W3037542376A5087231010 @default.
• W3037542376 hasBestOaLocation W30375423761 @default.
• W3037542376 hasConcept C117896860 @default.
• W3037542376 hasConcept C121332964 @default.
• W3037542376 hasConcept C126322002 @default.
• W3037542376 hasConcept C146357865 @default.
• W3037542376 hasConcept C151730666 @default.
• W3037542376 hasConcept C151800584 @default.
• W3037542376 hasConcept C173906292 @default.
• W3037542376 hasConcept C1862650 @default.
• W3037542376 hasConcept C23131810 @default.
• W3037542376 hasConcept C41008148 @default.
• W3037542376 hasConcept C44154836 @default.
• W3037542376 hasConcept C44249647 @default.
• W3037542376 hasConcept C71924100 @default.
• W3037542376 hasConcept C74650414 @default.
• W3037542376 hasConcept C86803240 @default.
• W3037542376 hasConcept C99476002 @default.
• W3037542376 hasConcept C99508421 @default.
• W3037542376 hasConceptScore W3037542376C117896860 @default.
• W3037542376 hasConceptScore W3037542376C121332964 @default.
• W3037542376 hasConceptScore W3037542376C126322002 @default.
• W3037542376 hasConceptScore W3037542376C146357865 @default.
• W3037542376 hasConceptScore W3037542376C151730666 @default.
• W3037542376 hasConceptScore W3037542376C151800584 @default.
• W3037542376 hasConceptScore W3037542376C173906292 @default.
• W3037542376 hasConceptScore W3037542376C1862650 @default.
• W3037542376 hasConceptScore W3037542376C23131810 @default.
• W3037542376 hasConceptScore W3037542376C41008148 @default.
• W3037542376 hasConceptScore W3037542376C44154836 @default.
• W3037542376 hasConceptScore W3037542376C44249647 @default.
• W3037542376 hasConceptScore W3037542376C71924100 @default.
• W3037542376 hasConceptScore W3037542376C74650414 @default.
• W3037542376 hasConceptScore W3037542376C86803240 @default.
• W3037542376 hasConceptScore W3037542376C99476002 @default.
• W3037542376 hasConceptScore W3037542376C99508421 @default.
• W3037542376 hasLocation W30375423761 @default.
• W3037542376 hasLocation W30375423762 @default.
• W3037542376 hasLocation W30375423763 @default.
• W3037542376 hasLocation W30375423764 @default.
• W3037542376 hasLocation W30375423765 @default.
• W3037542376 hasLocation W30375423766 @default.
• W3037542376 hasLocation W30375423767 @default.
• W3037542376 hasOpenAccess W3037542376 @default.
• W3037542376 hasPrimaryLocation W30375423761 @default.
• W3037542376 hasRelatedWork W1954924192 @default.
• W3037542376 hasRelatedWork W2009398857 @default.
• W3037542376 hasRelatedWork W2093541729 @default.
• W3037542376 hasRelatedWork W2394835211 @default.
• W3037542376 hasRelatedWork W2550361543 @default.
• W3037542376 hasRelatedWork W2591664903 @default.
• W3037542376 hasRelatedWork W2839643714 @default.
• W3037542376 hasRelatedWork W3029047068 @default.
• W3037542376 hasRelatedWork W4250474584 @default.
• W3037542376 hasRelatedWork W4381333469 @default.

• next