FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037606541> ?p ?o ?g. }

• W3037606541 endingPage "8" @default.
• W3037606541 startingPage "1" @default.
• W3037606541 abstract "In addition to the clinical parameters, immune-inflammatory markers have emerged as prognostic factors in patients with advanced biliary tract cancer (ABC). The recently proposed A.L.A.N. score combines both in an easily applicable manner. The aim of this study was to perform the first external evaluation of this score.All patients from our clinical registry unit who had unresectable ABC underwent first-line chemotherapy from 2006 to 2018 and met the inclusion criteria of the original study were included (n = 74). The A.L.A.N. score comprises the following parameters: actual neutrophil count, lymphocyte-to-monocyte ratio, albumin, and neutrophil-to-lymphocyte ratio (A.L.A.N.). Univariate and multivariate hazard regression analyses were performed to evaluate the score's parameters regarding overall survival (OS). The concordance index (C-index) and integrated Brier score (IBS) were calculated to evaluate the score's predictive performance.Low, intermediate, and high A.L.A.N. scores corresponded to median OS of 21.9, 11.4, and 4.3 months, respectively, resulting in a significant risk stratification (log-rank p=0.017). In multivariate analysis, a high-risk A.L.A.N. score remained an independent predictor of poor survival (p=0.016). Neutrophil-to-lymphocyte ratio was not a significant factor for poor OS in the analyses in the cohort. The score's ability to predict individual patient survival was only moderate with a C-index of 0.63.The A.L.A.N. score can be used to identify risk groups with a poor prognosis prior to the start of chemotherapy. However, the ability of the score to predict individual patient outcome was only moderate; thus, it may only serve as a minor component in the complex interdisciplinary discussion." @default.
• W3037606541 created "2020-07-02" @default.
• W3037606541 creator A5002788152 @default.
• W3037606541 creator A5004228804 @default.
• W3037606541 creator A5004960010 @default.
• W3037606541 creator A5009529288 @default.
• W3037606541 creator A5015991893 @default.
• W3037606541 creator A5019118329 @default.
• W3037606541 creator A5050747020 @default.
• W3037606541 creator A5063444447 @default.
• W3037606541 creator A5068173610 @default.
• W3037606541 creator A5072847679 @default.
• W3037606541 creator A5080463704 @default.
• W3037606541 date "2020-06-23" @default.
• W3037606541 modified "2023-10-06" @default.
• W3037606541 title "Risk Stratification in Advanced Biliary Tract Cancer: Validation of the A.L.A.N. Score" @default.
• W3037606541 cites W138318583 @default.
• W3037606541 cites W1508860390 @default.
• W3037606541 cites W1606619963 @default.
• W3037606541 cites W1775323748 @default.
• W3037606541 cites W1857440086 @default.
• W3037606541 cites W1982109465 @default.
• W3037606541 cites W1996484986 @default.
• W3037606541 cites W1997893645 @default.
• W3037606541 cites W2019996003 @default.
• W3037606541 cites W2028700227 @default.
• W3037606541 cites W2035515971 @default.
• W3037606541 cites W2061825208 @default.
• W3037606541 cites W2078271269 @default.
• W3037606541 cites W2091253378 @default.
• W3037606541 cites W2102335858 @default.
• W3037606541 cites W2108325039 @default.
• W3037606541 cites W2112347626 @default.
• W3037606541 cites W2115261608 @default.
• W3037606541 cites W2120579447 @default.
• W3037606541 cites W2124631712 @default.
• W3037606541 cites W2141078344 @default.
• W3037606541 cites W2144922697 @default.
• W3037606541 cites W2147114335 @default.
• W3037606541 cites W2151650153 @default.
• W3037606541 cites W2168251084 @default.
• W3037606541 cites W2203118396 @default.
• W3037606541 cites W2291808534 @default.
• W3037606541 cites W2342730850 @default.
• W3037606541 cites W2416032491 @default.
• W3037606541 cites W2425155949 @default.
• W3037606541 cites W2560678905 @default.
• W3037606541 cites W2596296725 @default.
• W3037606541 cites W2622965133 @default.
• W3037606541 cites W2733037502 @default.
• W3037606541 cites W2762253923 @default.
• W3037606541 cites W2802992541 @default.
• W3037606541 cites W2805136492 @default.
• W3037606541 cites W2894827508 @default.
• W3037606541 cites W2897896046 @default.
• W3037606541 cites W2902476919 @default.
• W3037606541 cites W2944813003 @default.
• W3037606541 cites W2954759555 @default.
• W3037606541 doi "https://doi.org/10.1155/2020/6180613" @default.
• W3037606541 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7330642" @default.
• W3037606541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32684933" @default.
• W3037606541 hasPublicationYear "2020" @default.
• W3037606541 type Work @default.
• W3037606541 sameAs 3037606541 @default.
• W3037606541 citedByCount "3" @default.
• W3037606541 countsByYear W30376065412022 @default.
• W3037606541 countsByYear W30376065412023 @default.
• W3037606541 crossrefType "journal-article" @default.
• W3037606541 hasAuthorship W3037606541A5002788152 @default.
• W3037606541 hasAuthorship W3037606541A5004228804 @default.
• W3037606541 hasAuthorship W3037606541A5004960010 @default.
• W3037606541 hasAuthorship W3037606541A5009529288 @default.
• W3037606541 hasAuthorship W3037606541A5015991893 @default.
• W3037606541 hasAuthorship W3037606541A5019118329 @default.
• W3037606541 hasAuthorship W3037606541A5050747020 @default.
• W3037606541 hasAuthorship W3037606541A5063444447 @default.
• W3037606541 hasAuthorship W3037606541A5068173610 @default.
• W3037606541 hasAuthorship W3037606541A5072847679 @default.
• W3037606541 hasAuthorship W3037606541A5080463704 @default.
• W3037606541 hasBestOaLocation W30376065411 @default.
• W3037606541 hasConcept C105795698 @default.
• W3037606541 hasConcept C11783203 @default.
• W3037606541 hasConcept C121608353 @default.
• W3037606541 hasConcept C126322002 @default.
• W3037606541 hasConcept C143998085 @default.
• W3037606541 hasConcept C144301174 @default.
• W3037606541 hasConcept C160798450 @default.
• W3037606541 hasConcept C161584116 @default.
• W3037606541 hasConcept C199163554 @default.
• W3037606541 hasConcept C207103383 @default.
• W3037606541 hasConcept C2777761686 @default.
• W3037606541 hasConcept C2778963024 @default.
• W3037606541 hasConcept C2779134260 @default.
• W3037606541 hasConcept C2780258809 @default.
• W3037606541 hasConcept C3017919176 @default.
• W3037606541 hasConcept C33923547 @default.
• W3037606541 hasConcept C35405484 @default.
• W3037606541 hasConcept C38180746 @default.

• next