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• W3037626265 abstract "Background Neonatal infections with Cronobacter sakazakii have recently been associated with the consumption of expressed human milk. Study Aims (1) To evaluate whether human milk has antimicrobial capacity against C. sakazakii and (2) to determine the stability of its capacity when it is subjected to various treatments. Methods The antimicrobial capacity of human milk against C. sakazakii was evaluated using an observational, cross-sectional, comparative design. Mature human milk samples ( N = 29) were subjected to different treatments. After incubation at 37°C for 72 hr, samples were compared with fresh milk on the stability of their antimicrobial capacity. Two-way analysis of variance (ANOVA) was performed. Results In fresh milk, counts of C. sakazakii were reduced by 47.26% ( SD = 6.74) compared to controls. In treated milk, reductions were: refrigeration at 4°C for 72 hr ( M = 33.84, SD = 13.84), freezing at –20°C for 1, 2, and 3 months ( M = 40.31, SD = 9.10; M = 35.96, SD = 9.39; M = 26.20, SD = 13.55, respectively), Holder pasteurization ( M = 23.56, SD = 15.61), and human milk bank treatment with ( M = 14.37, SD = 18.02) and without bovine fortifier ( M = 3.70, SD = 23.83). There were significant differences ( p < .05) between fresh and treated milk. Conclusions Human milk has antimicrobial capacity against C. sakazakii. However, its capacity is negatively influenced by common preservation and hygienization methods. Milk should be stored refrigerated for a maximum of 72 hr or frozen for a short period of time." @default.
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• W3037626265 date "2020-06-24" @default.
• W3037626265 modified "2023-10-16" @default.
• W3037626265 title "Stability of the Antimicrobial Capacity of Human Milk Against Cronobacter Sakazakii During Handling" @default.
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• W3037626265 doi "https://doi.org/10.1177/0890334420932574" @default.
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