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- W3037781933 abstract "Herpes simplex virus type 2 (HSV-2) causes recurrent lesions in the anogenital area that may be transmitted through sexual encounters. Nucleoside analogs, such as acyclovir (ACV), are currently prescribed clinically to curb this infection. However, in some cases, reduced efficacy has been observed due to the emergence of resistance against these drugs. In our previous study, we reported the discovery of a novel anti-HSV-1 small molecule, BX795, which was originally used as an inhibitor of TANK-binding kinase 1 (TBK1)." @default.
- W3037781933 created "2020-07-02" @default.
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- W3037781933 date "2020-08-20" @default.
- W3037781933 modified "2023-10-17" @default.
- W3037781933 title "<i>In Vitro</i> and <i>In Vivo</i> Activity, Tolerability, and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus 2 Genital Infection" @default.
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- W3037781933 doi "https://doi.org/10.1128/aac.00245-20" @default.
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