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- W3037827122 abstract "Objective: The aim of our study was to identify whether body mass index (BMI), waist circumference (WC) or waist-to-height ratio (WHtR) is the best predictor of left ventricular hypertrophy described by echocardiogram findings. Design and method: The study analyzed a cohort of 4866 middle-aged patients taking part in the second stage of the Lithuanian High Cardiovascular Risk prevention program (LitHiR). The patients were divided into obese and non-obese groups based on BMI (division point at 30), WHtR (division point at 0.577) and WC (division point at 88 cm for female and 102 cm for male participants) and later compared regarding values of echocardiogram parameters. Left ventricular mass (LVM), left ventricular end-diastolic diameter (LVEDD), left ventricular posterior wall thickness (PWT) and interventricular septum thickness (IVS) served as the dependent variables of the study. Stepwise multiple regression analysis was used to establish the relationship between the aforementioned dependent and the independent obesity-related variables. Results: 2972 (61.6 %) of the participants were female. The mean age of the study population was 53.96 ± 6.23 years. 2983 (61.3 %), 590 (12.1 %), 3053 (62.7 %) and 3319 (64.1 %) of the patients presented with increased LVM, LVEDD, PWT and IVS values, respectively. Patients of both genders within the three obese groups described by BMI, WC and WHtR had significantly higher mean LVM, LVEDD, PWT and IVS values when compared to subjects in the non-obese groups (P-value < 0.001). Stepwise multiple regression analysis declared BMI as the predictor of the best predictive value of changes in all of the geometric left ventricular parameters, whereas WHtR was of the least significance. Conclusions: A large proportion of the middle-aged high cardiovascular risk study population presented with echocardiogram changes indicative of left ventricular hypertrophy. Obesity was associated with increased LVM, LVEDD, PWT and IVS values while the most accurate obesity-related predictor of these changes was BMI." @default.
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- W3037827122 date "2015-06-01" @default.
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- W3037827122 title "PP.04.21" @default.
- W3037827122 doi "https://doi.org/10.1097/01.hjh.0000467837.00956.95" @default.
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