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• W3037833159 startingPage "1618" @default.
• W3037833159 abstract "Brucellosis caused by Brucella melitensis is considered to be one of the most important zoonotic diseases in China. In this study, Conventional bio-typing, MLVA (multiple locus variable-number tandem repeat analysis), and WGS (whole-genome sequencing)-SNP (single nucleotide polymorphism) were used to study the genetic similarity of B. melitensis in northern and southern China and analyze its relationship with worldwide lineages. Currently, the distribution of species/biovars of B. melitensis has obviously changed, and B. melitensis has become the dominant species in southern regions of China. Strains from the southern had a common geographic origin with strains from the northern. Many MLVA-16 events were shared in the genotypes of the southern and northern strains, suggest that genotypic movement occurred from north to south. Based on WGS-SNP analysis, strains from different provinces were closely related and may have descended from one common ancestor, suggests that the southern strains originated from northern China. These data indicate that B. melitensis is a latent “travel bacterium” that spread and expanded from North China to South China. Moreover, B. melitensis strains from China are also genetically related to strains from other Asian regions (Kazakhstan, Russia, Mongolia, and India). The movement of infected sheep and their products requires control." @default.
• W3037833159 created "2020-07-02" @default.
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• W3037833159 date "2020-01-01" @default.
• W3037833159 modified "2023-10-13" @default.
• W3037833159 title "<i>Brucella melitensis</i>, a latent “travel bacterium,” continual spread and expansion from Northern to Southern China and its relationship to worldwide lineages" @default.
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• W3037833159 doi "https://doi.org/10.1080/22221751.2020.1788995" @default.
• W3037833159 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7473006" @default.
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• W3037833159 hasPublicationYear "2020" @default.
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