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• W3037858231 endingPage "e0008341" @default.
• W3037858231 startingPage "e0008341" @default.
• W3037858231 abstract "Tsetse fly exhibit species-specific olfactory uniqueness potentially underpinned by differences in their chemosensory protein repertoire. We assessed 1) expansions of chemosensory protein orthologs in Glossina morsitans morsitans, Glossina pallidipes, Glossina austeni, Glossina palpalis gambiensis, Glossina fuscipes fuscipes and Glossina brevipalpis tsetse fly species using Cafe analysis (to identify species-specific expansions) and 2) differential expressions of the orthologs and associated proteins in male G. m. morsitans antennae and head tissues using RNA-Seq approaches (to establish associated functional molecular pathways). We established accelerated and significant (P 90% of chemosensory transcripts) included cilium-associated mechanoreceptors, chemo-sensation, neuronal controlled growth/differentiation and regeneration/responses to stress. The expanded and tsetse fly species specific orthologs includes those associated with known tsetse fly responsive ligands (4-methyl phenol, 4-propyl phenol, acetic acid, butanol and carbon dioxide) and potential tsetse fly species-specific responsive ligands (2-oxopentanoic acid, phenylacetaldehyde, hydroxycinnamic acid, 2-heptanone, caffeine, geosmin, DEET and (cVA) pheromone). Some of the orthologs can potentially modulate several tsetse fly species-specific behavioral (male-male courtship, hunger/host seeking, cool avoidance, hygrosensory and feeding) phenotypes. The putative tsetse fly specific chemosensory gene orthologs and their respective ligands provide candidate gene targets and kairomones for respective downstream functional genomic and field evaluations that can effectively expand toolbox of species-specific tsetse fly attractants, repellents and other tsetse fly behavioral modulators." @default.
• W3037858231 created "2020-07-02" @default.
• W3037858231 creator A5010461509 @default.
• W3037858231 creator A5022540425 @default.
• W3037858231 creator A5030855830 @default.
• W3037858231 creator A5037394498 @default.
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• W3037858231 creator A5069088141 @default.
• W3037858231 creator A5070478605 @default.
• W3037858231 creator A5078875814 @default.
• W3037858231 creator A5080672651 @default.
• W3037858231 creator A5085102265 @default.
• W3037858231 date "2020-06-26" @default.
• W3037858231 modified "2023-09-24" @default.
• W3037858231 title "Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in Glossina morsitans morsitans tsetse fly" @default.
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