Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037859040> ?p ?o ?g. }
- W3037859040 endingPage "15590" @default.
- W3037859040 startingPage "15581" @default.
- W3037859040 abstract "Significance Aging is associated with a myriad of changes at all levels of organization of an organism. However, how it affects protein synthesis, a major metabolic activity of the cell, is unknown. We discovered deregulation of protein synthesis and ribosome biogenesis machinery specifically at the translational level with age. Moreover, ribosomes were depleted in the vicinity of start codons and increased near stop codons. These findings reveal systematic, multilevel deregulation in gene expression and protein synthesis, showing how this major cellular process declines with age." @default.
- W3037859040 created "2020-07-02" @default.
- W3037859040 creator A5010080171 @default.
- W3037859040 creator A5038333464 @default.
- W3037859040 creator A5044225237 @default.
- W3037859040 creator A5054297859 @default.
- W3037859040 creator A5062435496 @default.
- W3037859040 creator A5066126356 @default.
- W3037859040 date "2020-06-23" @default.
- W3037859040 modified "2023-10-16" @default.
- W3037859040 title "Multifaceted deregulation of gene expression and protein synthesis with age" @default.
- W3037859040 cites W1533133582 @default.
- W3037859040 cites W1697139149 @default.
- W3037859040 cites W1966082815 @default.
- W3037859040 cites W1980217195 @default.
- W3037859040 cites W1994595131 @default.
- W3037859040 cites W1995205742 @default.
- W3037859040 cites W2007006796 @default.
- W3037859040 cites W2025569664 @default.
- W3037859040 cites W2038654926 @default.
- W3037859040 cites W2042087846 @default.
- W3037859040 cites W2046872786 @default.
- W3037859040 cites W2056772716 @default.
- W3037859040 cites W2061361190 @default.
- W3037859040 cites W2069099470 @default.
- W3037859040 cites W2071849521 @default.
- W3037859040 cites W2079517684 @default.
- W3037859040 cites W2082564115 @default.
- W3037859040 cites W2085663116 @default.
- W3037859040 cites W2099290136 @default.
- W3037859040 cites W2104431515 @default.
- W3037859040 cites W2108700752 @default.
- W3037859040 cites W2110719003 @default.
- W3037859040 cites W2114104545 @default.
- W3037859040 cites W2117970703 @default.
- W3037859040 cites W2131844826 @default.
- W3037859040 cites W2132816368 @default.
- W3037859040 cites W2136225615 @default.
- W3037859040 cites W2136272779 @default.
- W3037859040 cites W2136597136 @default.
- W3037859040 cites W2142282262 @default.
- W3037859040 cites W2144968983 @default.
- W3037859040 cites W2149236492 @default.
- W3037859040 cites W2149524489 @default.
- W3037859040 cites W2155933519 @default.
- W3037859040 cites W2156030059 @default.
- W3037859040 cites W2160215304 @default.
- W3037859040 cites W2160718564 @default.
- W3037859040 cites W2168783201 @default.
- W3037859040 cites W2289876562 @default.
- W3037859040 cites W2439659817 @default.
- W3037859040 cites W2520675467 @default.
- W3037859040 cites W2605265780 @default.
- W3037859040 cites W2606227689 @default.
- W3037859040 cites W2625191040 @default.
- W3037859040 cites W2731940811 @default.
- W3037859040 cites W2736023044 @default.
- W3037859040 cites W2736133820 @default.
- W3037859040 cites W2771265500 @default.
- W3037859040 cites W2783734426 @default.
- W3037859040 cites W2792287150 @default.
- W3037859040 cites W2884081989 @default.
- W3037859040 cites W2886122923 @default.
- W3037859040 cites W2892229852 @default.
- W3037859040 cites W2904330826 @default.
- W3037859040 cites W2913940235 @default.
- W3037859040 cites W2953016965 @default.
- W3037859040 cites W2953026039 @default.
- W3037859040 cites W2969975949 @default.
- W3037859040 doi "https://doi.org/10.1073/pnas.2001788117" @default.
- W3037859040 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7354943" @default.
- W3037859040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32576685" @default.
- W3037859040 hasPublicationYear "2020" @default.
- W3037859040 type Work @default.
- W3037859040 sameAs 3037859040 @default.
- W3037859040 citedByCount "67" @default.
- W3037859040 countsByYear W30378590402020 @default.
- W3037859040 countsByYear W30378590402021 @default.
- W3037859040 countsByYear W30378590402022 @default.
- W3037859040 countsByYear W30378590402023 @default.
- W3037859040 crossrefType "journal-article" @default.
- W3037859040 hasAuthorship W3037859040A5010080171 @default.
- W3037859040 hasAuthorship W3037859040A5038333464 @default.
- W3037859040 hasAuthorship W3037859040A5044225237 @default.
- W3037859040 hasAuthorship W3037859040A5054297859 @default.
- W3037859040 hasAuthorship W3037859040A5062435496 @default.
- W3037859040 hasAuthorship W3037859040A5066126356 @default.
- W3037859040 hasBestOaLocation W30378590401 @default.
- W3037859040 hasConcept C104317684 @default.
- W3037859040 hasConcept C105580179 @default.
- W3037859040 hasConcept C131934819 @default.
- W3037859040 hasConcept C139719470 @default.
- W3037859040 hasConcept C149364088 @default.
- W3037859040 hasConcept C150194340 @default.
- W3037859040 hasConcept C162324750 @default.
- W3037859040 hasConcept C165864922 @default.
- W3037859040 hasConcept C2779419633 @default.
- W3037859040 hasConcept C3675279 @default.