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- W3037860829 abstract "Objective: Increased pulse pressure (PP) is associated with increased arterial stiffness, however, its predictor value of new cardiovascular events in patients hospitalized for acute coronary syndrome (ACS) has not been established. The objective of this study is to evaluate PP as a predictor of stroke in patients hospitalized for ACS. Design and method: An observational retrospective study of 508 patients admitted to the coronary care unit for ACS for 3 consecutive years. The follow-up lasted until 31st october 2014 or until another event (new ACS, stroke, hospitalization for heart failure, hospitalization for arrhythmic event or death). The primary endpoint was defined as ischemic stroke documented by computed tomography. Results: The study included 508 patients, 72.3% male, mean age 66 ± 13 years. During the median follow-up of 30 ± 18 months 138 new events were recorded, 15 of which were strokes. Multivariate Cox analysis adjusted for potential confounders (sex, diabetes, hypertension, dyslipidemia, obesity, smoking and heart rate on admission) demonstrated that only PP and systolic blood pressure at admission (with Hazard respective ratio of 1.024 and 1.024 and p < 0.05) were predictors of stroke. The analysis of t-student showed that women had a mean value of PP superior to men as well as diabetics versus non-diabetics, hypertensive versus normotensive, obese versus non-obese. Conclusions: This study showed that PP may have predictive value of stroke in patients hospitalized for ACS." @default.
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- W3037860829 date "2015-06-01" @default.
- W3037860829 modified "2023-09-26" @default.
- W3037860829 title "PP.34.25" @default.
- W3037860829 doi "https://doi.org/10.1097/01.hjh.0000468779.60515.d9" @default.
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