FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037887515> ?p ?o ?g. }

• W3037887515 endingPage "707" @default.
• W3037887515 startingPage "700" @default.
• W3037887515 abstract "Traumatic peripheral nerve injuries (PNI) often result in severe neuropathic pain which typically becomes chronic, is recalcitrant to common analgesics, and is associated with sleep disturbances, anxiety, and depression. Pharmacological treatments proven to be effective against neuropathic pain are not well tolerated due to side effects. Neuromodulative interventions such as peripheral nerve or spinal cord stimulation have generated mixed results and may be limited by reduced somatotopic specificity. Dorsal root ganglion (DRG) stimulation may be more effective in this etiology.Twenty-seven patients were trialed with a DRG neurostimulation system for PNI; trial success (defined as ≥50% pain relief) was 85%, and 23 patients received a permanent stimulator. However, 36-month outcome data was only available for 21 patients. Pain, quality of life, mental and physical function, and opioid usage were assessed at baseline and at 3-, 6-, 12-, 18-, 24-, and 36 months post-permanent implant. Implant-related complications were also documented.Compared to baseline, we observed a significant pain relief (p < 0.001) at 3 (58%), 12 (66%), 18 (69%), 24 (71%), and 36 months (73%) in 21 patients (52.5 ± 14.2 years; 12 female), respectively. Mental and physical function showed immediate and sustained improvements. Participants reported improvements in quality of life. Opioid dosage reduced significantly (p < 0.001) at 3 (30%), 12 (93%), 18 (98%), 24 (99%), and 36 months (99%), and 20 of 21 patients were completely opioid-free after 36 months. There were five lead migrations and two electrode fractures (corrected by surgical intervention) and one wound infection (conservatively managed).DRG neuromodulation appears to be a safe, effective, and durable option for treating neuropathic pain caused by PNI. The treatment allows cessation of often ineffective pharmacotherapy (including opioid misuse) and significantly improves quality of life." @default.
• W3037887515 created "2020-07-02" @default.
• W3037887515 creator A5006851774 @default.
• W3037887515 creator A5029992611 @default.
• W3037887515 creator A5078697016 @default.
• W3037887515 date "2021-06-01" @default.
• W3037887515 modified "2023-10-14" @default.
• W3037887515 title "Three-Year Outcomes After Dorsal Root Ganglion Stimulation in the Treatment of Neuropathic Pain After Peripheral Nerve Injury of Upper and Lower Extremities" @default.
• W3037887515 cites W1535252741 @default.
• W3037887515 cites W1712935512 @default.
• W3037887515 cites W1766166977 @default.
• W3037887515 cites W1949425569 @default.
• W3037887515 cites W1981120831 @default.
• W3037887515 cites W1985977280 @default.
• W3037887515 cites W2017299617 @default.
• W3037887515 cites W2019751442 @default.
• W3037887515 cites W2030034123 @default.
• W3037887515 cites W2030392551 @default.
• W3037887515 cites W2104746404 @default.
• W3037887515 cites W2104818454 @default.
• W3037887515 cites W2107636577 @default.
• W3037887515 cites W2109005841 @default.
• W3037887515 cites W2116494341 @default.
• W3037887515 cites W2122097870 @default.
• W3037887515 cites W2124105819 @default.
• W3037887515 cites W2130113356 @default.
• W3037887515 cites W2136273883 @default.
• W3037887515 cites W2154140619 @default.
• W3037887515 cites W2154693681 @default.
• W3037887515 cites W2164513741 @default.
• W3037887515 cites W2171060388 @default.
• W3037887515 cites W2172211667 @default.
• W3037887515 cites W2197461111 @default.
• W3037887515 cites W2316569153 @default.
• W3037887515 cites W2321971569 @default.
• W3037887515 cites W2551942375 @default.
• W3037887515 cites W2562935008 @default.
• W3037887515 cites W2564952377 @default.
• W3037887515 cites W2743148427 @default.
• W3037887515 cites W2748476908 @default.
• W3037887515 cites W2757921639 @default.
• W3037887515 cites W2773604730 @default.
• W3037887515 cites W2789922692 @default.
• W3037887515 cites W2790571424 @default.
• W3037887515 cites W2803291210 @default.
• W3037887515 cites W2887672367 @default.
• W3037887515 cites W2894758726 @default.
• W3037887515 cites W2896769073 @default.
• W3037887515 cites W2896951195 @default.
• W3037887515 cites W2905040483 @default.
• W3037887515 cites W2911142979 @default.
• W3037887515 cites W2915959214 @default.
• W3037887515 cites W2922202156 @default.
• W3037887515 cites W2930814409 @default.
• W3037887515 cites W2947321543 @default.
• W3037887515 cites W2964182659 @default.
• W3037887515 cites W2970933289 @default.
• W3037887515 cites W2988129653 @default.
• W3037887515 cites W3005583617 @default.
• W3037887515 cites W3007382527 @default.
• W3037887515 cites W3009708857 @default.
• W3037887515 cites W3011095075 @default.
• W3037887515 cites W3023503422 @default.
• W3037887515 cites W2066781380 @default.
• W3037887515 doi "https://doi.org/10.1111/ner.13222" @default.
• W3037887515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32573868" @default.
• W3037887515 hasPublicationYear "2021" @default.
• W3037887515 type Work @default.
• W3037887515 sameAs 3037887515 @default.
• W3037887515 citedByCount "20" @default.
• W3037887515 countsByYear W30378875152020 @default.
• W3037887515 countsByYear W30378875152021 @default.
• W3037887515 countsByYear W30378875152022 @default.
• W3037887515 countsByYear W30378875152023 @default.
• W3037887515 crossrefType "journal-article" @default.
• W3037887515 hasAuthorship W3037887515A5006851774 @default.
• W3037887515 hasAuthorship W3037887515A5029992611 @default.
• W3037887515 hasAuthorship W3037887515A5078697016 @default.
• W3037887515 hasBestOaLocation W30378875151 @default.
• W3037887515 hasConcept C118552586 @default.
• W3037887515 hasConcept C126322002 @default.
• W3037887515 hasConcept C139719470 @default.
• W3037887515 hasConcept C141071460 @default.
• W3037887515 hasConcept C159110408 @default.
• W3037887515 hasConcept C162324750 @default.
• W3037887515 hasConcept C170493617 @default.
• W3037887515 hasConcept C1862650 @default.
• W3037887515 hasConcept C24998067 @default.
• W3037887515 hasConcept C2775991916 @default.
• W3037887515 hasConcept C2776281502 @default.
• W3037887515 hasConcept C2776443511 @default.
• W3037887515 hasConcept C2776867660 @default.
• W3037887515 hasConcept C2776880756 @default.
• W3037887515 hasConcept C2777107010 @default.
• W3037887515 hasConcept C2778334475 @default.
• W3037887515 hasConcept C2779951463 @default.
• W3037887515 hasConcept C2780375056 @default.
• W3037887515 hasConcept C2780775167 @default.

• next