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• W3037929239 abstract "Abstract Radiotherapy is a pivotal component in the curative treatment of patients with localised cancer and isolated metastasis, as well as being used as a palliative strategy for patients with disseminated disease. The clinical efficacy of radiotherapy has traditionally been attributed to the local effects of ionising radiation, which induces cell death by directly and indirectly inducing DNA damage, but substantial work has uncovered an unexpected and dual relationship between tumour irradiation and the host immune system. In clinical practice, it is, therefore, tempting to tailor immunotherapies with radiotherapy in order to synergise innate and adaptive immunity against cancer cells, as well as to bypass immune tolerance and exhaustion, with the aim of facilitating tumour regression. However, our understanding of how radiation impacts on immune system activation is still in its early stages, and concerns and challenges regarding therapeutic applications still need to be overcome. With the increasing use of immunotherapy and its common combination with ionising radiation, this review briefly delineates current knowledge about the non-targeted effects of radiotherapy, and aims to provide insights, at the preclinical level, into the mechanisms that are involved with the potential to yield clinically relevant combinatorial approaches of radiotherapy and immunotherapy." @default.
• W3037929239 created "2020-07-02" @default.
• W3037929239 creator A5001628805 @default.
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• W3037929239 date "2020-06-25" @default.
• W3037929239 modified "2023-10-18" @default.
• W3037929239 title "Radiation-induced bystander and abscopal effects: important lessons from preclinical models" @default.
• W3037929239 cites W1258890488 @default.
• W3037929239 cites W1524125877 @default.
• W3037929239 cites W1601764158 @default.
• W3037929239 cites W1741548448 @default.
• W3037929239 cites W1890350389 @default.
• W3037929239 cites W1943338723 @default.
• W3037929239 cites W1970786411 @default.
• W3037929239 cites W1973296540 @default.
• W3037929239 cites W1979690614 @default.
• W3037929239 cites W1983882042 @default.
• W3037929239 cites W1992512767 @default.
• W3037929239 cites W1994826332 @default.
• W3037929239 cites W1997122877 @default.
• W3037929239 cites W1999020268 @default.
• W3037929239 cites W1999404261 @default.
• W3037929239 cites W2001973174 @default.
• W3037929239 cites W2002760403 @default.
• W3037929239 cites W2008771785 @default.
• W3037929239 cites W2010916968 @default.
• W3037929239 cites W2014433188 @default.
• W3037929239 cites W2022837929 @default.
• W3037929239 cites W2024626836 @default.
• W3037929239 cites W2025421597 @default.
• W3037929239 cites W2028458507 @default.
• W3037929239 cites W2032166347 @default.
• W3037929239 cites W2034017959 @default.
• W3037929239 cites W2036643295 @default.
• W3037929239 cites W2042182299 @default.
• W3037929239 cites W2044890358 @default.
• W3037929239 cites W2045849720 @default.
• W3037929239 cites W2053393698 @default.
• W3037929239 cites W2054749775 @default.
• W3037929239 cites W2054995801 @default.
• W3037929239 cites W2055720377 @default.
• W3037929239 cites W2061436674 @default.
• W3037929239 cites W2064442490 @default.
• W3037929239 cites W2066195250 @default.
• W3037929239 cites W2067509761 @default.
• W3037929239 cites W2068634088 @default.
• W3037929239 cites W2076436390 @default.
• W3037929239 cites W2076866768 @default.
• W3037929239 cites W2077499132 @default.
• W3037929239 cites W2078353701 @default.
• W3037929239 cites W2082201648 @default.
• W3037929239 cites W2084142018 @default.
• W3037929239 cites W2087671265 @default.
• W3037929239 cites W2089054536 @default.
• W3037929239 cites W2091191929 @default.
• W3037929239 cites W2097942385 @default.
• W3037929239 cites W2105076285 @default.
• W3037929239 cites W2108387330 @default.
• W3037929239 cites W2108789863 @default.
• W3037929239 cites W2117280704 @default.
• W3037929239 cites W2117878645 @default.
• W3037929239 cites W2120426523 @default.
• W3037929239 cites W2123894372 @default.
• W3037929239 cites W2124730679 @default.
• W3037929239 cites W2127733313 @default.
• W3037929239 cites W2130211103 @default.
• W3037929239 cites W2132564070 @default.
• W3037929239 cites W2134427843 @default.
• W3037929239 cites W2135736919 @default.
• W3037929239 cites W2136879408 @default.
• W3037929239 cites W2137289789 @default.
• W3037929239 cites W2139214771 @default.
• W3037929239 cites W2140231263 @default.
• W3037929239 cites W2145736817 @default.
• W3037929239 cites W2145922436 @default.
• W3037929239 cites W2153929368 @default.
• W3037929239 cites W2159094759 @default.
• W3037929239 cites W2160144435 @default.
• W3037929239 cites W2163035374 @default.
• W3037929239 cites W2178785249 @default.
• W3037929239 cites W2179058242 @default.
• W3037929239 cites W2257179721 @default.
• W3037929239 cites W2265258187 @default.
• W3037929239 cites W2280306471 @default.
• W3037929239 cites W2298272175 @default.
• W3037929239 cites W2314254896 @default.
• W3037929239 cites W2346380472 @default.
• W3037929239 cites W2411685931 @default.
• W3037929239 cites W2512217706 @default.
• W3037929239 cites W2526282664 @default.
• W3037929239 cites W2528386527 @default.

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