Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037945904> ?p ?o ?g. }
- W3037945904 abstract "Within the tumor microenvironment, there is an intricate communication happening between tumor and stromal cells. This information exchange, in the form of cytokines, growth factors, extracellular vesicles, danger molecules, cell debris and other factors, is capable of modulating the function of immune cells. The triggering of specific responses, including phenotypic alterations, can ultimately result in either immune surveillance or tumor cell survival. Macrophages are a well-studied cell lineage illustrating the different cellular phenotypes possible, depending on the tumor microenvironmental context. While our understanding of macrophage responses is well documented in vitro, surprisingly, little work has been done to confirm these observations in the cancer microenvironment. In fact, there are examples of opposing reactions of macrophages to cytokines in cell culture and in vivo tumor settings. Additionally, it seems that different macrophage lineages, for example tissue-resident and monocyte-derived macrophages, respond differently to cytokines and other cancer-derived signals. In this review article, we will describe and discuss the diverging reports on how cancer cells influence monocyte-derived and tissue-resident macrophage traits in vivo." @default.
- W3037945904 created "2020-07-02" @default.
- W3037945904 creator A5037394787 @default.
- W3037945904 creator A5047213955 @default.
- W3037945904 creator A5056833266 @default.
- W3037945904 creator A5067752737 @default.
- W3037945904 date "2020-06-23" @default.
- W3037945904 modified "2023-10-05" @default.
- W3037945904 title "The Impact of the Cancer Microenvironment on Macrophage Phenotypes" @default.
- W3037945904 cites W1480188565 @default.
- W3037945904 cites W1526200347 @default.
- W3037945904 cites W1905169223 @default.
- W3037945904 cites W1908116487 @default.
- W3037945904 cites W1948478725 @default.
- W3037945904 cites W1963904011 @default.
- W3037945904 cites W1969057487 @default.
- W3037945904 cites W1997001753 @default.
- W3037945904 cites W2010813987 @default.
- W3037945904 cites W2017347652 @default.
- W3037945904 cites W2019954526 @default.
- W3037945904 cites W2023178963 @default.
- W3037945904 cites W2041189421 @default.
- W3037945904 cites W2055313665 @default.
- W3037945904 cites W2061545951 @default.
- W3037945904 cites W2071625709 @default.
- W3037945904 cites W2085357178 @default.
- W3037945904 cites W2085695854 @default.
- W3037945904 cites W2088434784 @default.
- W3037945904 cites W2096179876 @default.
- W3037945904 cites W2103950437 @default.
- W3037945904 cites W2114050989 @default.
- W3037945904 cites W2115713194 @default.
- W3037945904 cites W2125886792 @default.
- W3037945904 cites W2127224035 @default.
- W3037945904 cites W2140380746 @default.
- W3037945904 cites W2142242761 @default.
- W3037945904 cites W2150105131 @default.
- W3037945904 cites W2154434805 @default.
- W3037945904 cites W2159069239 @default.
- W3037945904 cites W2159903805 @default.
- W3037945904 cites W2161704645 @default.
- W3037945904 cites W2162444234 @default.
- W3037945904 cites W2163175900 @default.
- W3037945904 cites W2164142048 @default.
- W3037945904 cites W2165036434 @default.
- W3037945904 cites W2166760323 @default.
- W3037945904 cites W2167685929 @default.
- W3037945904 cites W2171769968 @default.
- W3037945904 cites W2175100525 @default.
- W3037945904 cites W2218403526 @default.
- W3037945904 cites W2301044272 @default.
- W3037945904 cites W2471236855 @default.
- W3037945904 cites W2506892818 @default.
- W3037945904 cites W2523680188 @default.
- W3037945904 cites W2539398141 @default.
- W3037945904 cites W2604465118 @default.
- W3037945904 cites W2605907314 @default.
- W3037945904 cites W2612537388 @default.
- W3037945904 cites W2711510694 @default.
- W3037945904 cites W2736034593 @default.
- W3037945904 cites W2738491178 @default.
- W3037945904 cites W2739501186 @default.
- W3037945904 cites W2749550628 @default.
- W3037945904 cites W2761458899 @default.
- W3037945904 cites W2765148841 @default.
- W3037945904 cites W2766746427 @default.
- W3037945904 cites W2770114721 @default.
- W3037945904 cites W2771972161 @default.
- W3037945904 cites W2786007302 @default.
- W3037945904 cites W2795073885 @default.
- W3037945904 cites W2795561878 @default.
- W3037945904 cites W2800494230 @default.
- W3037945904 cites W2800905301 @default.
- W3037945904 cites W2884363441 @default.
- W3037945904 cites W2898513675 @default.
- W3037945904 cites W2921355001 @default.
- W3037945904 cites W2924762180 @default.
- W3037945904 cites W2927199411 @default.
- W3037945904 cites W2931512726 @default.
- W3037945904 cites W2946918603 @default.
- W3037945904 cites W2947216697 @default.
- W3037945904 cites W2953819095 @default.
- W3037945904 cites W2967990981 @default.
- W3037945904 cites W2979760381 @default.
- W3037945904 cites W2990407981 @default.
- W3037945904 cites W3006438030 @default.
- W3037945904 cites W3154781712 @default.
- W3037945904 doi "https://doi.org/10.3389/fimmu.2020.01308" @default.
- W3037945904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7324670" @default.
- W3037945904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32655574" @default.
- W3037945904 hasPublicationYear "2020" @default.
- W3037945904 type Work @default.
- W3037945904 sameAs 3037945904 @default.
- W3037945904 citedByCount "18" @default.
- W3037945904 countsByYear W30379459042020 @default.
- W3037945904 countsByYear W30379459042021 @default.
- W3037945904 countsByYear W30379459042022 @default.
- W3037945904 countsByYear W30379459042023 @default.
- W3037945904 crossrefType "journal-article" @default.
- W3037945904 hasAuthorship W3037945904A5037394787 @default.