FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037972144> ?p ?o ?g. }

• W3037972144 abstract "Abstract Background Persistent and chronic diarrhea is difficult to treat, and infection is still the main cause. In this study, we investigate the application value of xTAG gastrointestinal pathogen panel (xTAG GPP) multiplex PCR in the early diagnosis of persistent and chronic diarrhea in children and to understand the epidemiology of intestinal diarrhea pathogens. Methods One hundred ninety-nine specimens were collected from Nanjing Children’s Hospital Affiliated to Nanjing Medical University (Nanjing, China). We compared the xTAG GPP multiplex PCR assay with traditional methods (culture, rapid enzyme immunoassay chromatography, and microscopic examination) and performed a statistical analysis. Results The positive rate of the xTAG GPP multiplex PCR assay of diarrhea specimens from 199 patients was 72.86% (145/199). The virus detection rate was 48.7%, and rotavirus A was the most common organism detected (34.67%), concentrated in winter, and was common in children. The second most common organism detected was norovirus GI/GII (20.6%). The positive rate of this bacteria was 40.2%, and Campylobacter (22.11%, 44/199) was most frequently detected. C. difficile toxins A/B and Salmonella was detected in 44 and 17 samples, respectively. Infections with Shigella occurred 4 times, and E. coli O157 was only detected once. Three samples were parasitic (1.51%), two samples were positive for Entamoeba histolytica , and one was positive for Cryptosporidium . Adenovirus 40/41, STEC, ETEC, Giardia , Yersinia enterocolitica and Vibrio cholerae were not detected. In total, 86 (43.2%) infected specimens with a single pathogen were detected. There were 59 coinfections (29.65% of the samples) of viruses and/or bacteria and/or parasites. Coinfections involved 49 double infections (24.62%), 9 triple infections (4.52%) and 1 quadruple infections (0.5%). Norovirus GI/GII was found to have the highest involvement, with 32 coinfections (16.08%). Conclusion The xTAG GPP multiplex PCR assay is simple, sensitive, and specific and can be used as a quick way to diagnose persistent and chronic diarrhea in children." @default.
• W3037972144 created "2020-07-02" @default.
• W3037972144 creator A5003580103 @default.
• W3037972144 creator A5020332409 @default.
• W3037972144 creator A5021237600 @default.
• W3037972144 creator A5037036377 @default.
• W3037972144 creator A5061488497 @default.
• W3037972144 creator A5063459637 @default.
• W3037972144 creator A5079061857 @default.
• W3037972144 creator A5081585606 @default.
• W3037972144 creator A5084888732 @default.
• W3037972144 date "2020-06-26" @default.
• W3037972144 modified "2023-10-08" @default.
• W3037972144 title "The application research of xTAG GPP multiplex PCR in the diagnosis of persistent and chronic diarrhea in children" @default.
• W3037972144 cites W1992943617 @default.
• W3037972144 cites W1999950003 @default.
• W3037972144 cites W2004625066 @default.
• W3037972144 cites W2013200403 @default.
• W3037972144 cites W2026425515 @default.
• W3037972144 cites W2029691788 @default.
• W3037972144 cites W2039814930 @default.
• W3037972144 cites W2040572811 @default.
• W3037972144 cites W2041068978 @default.
• W3037972144 cites W2075048866 @default.
• W3037972144 cites W2096394008 @default.
• W3037972144 cites W2114004043 @default.
• W3037972144 cites W2118280981 @default.
• W3037972144 cites W2145349119 @default.
• W3037972144 cites W2151473396 @default.
• W3037972144 cites W2162153565 @default.
• W3037972144 cites W2167174099 @default.
• W3037972144 cites W2171475272 @default.
• W3037972144 cites W2266271318 @default.
• W3037972144 cites W4254824685 @default.
• W3037972144 doi "https://doi.org/10.1186/s12887-020-02206-6" @default.
• W3037972144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7318512" @default.
• W3037972144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32590971" @default.
• W3037972144 hasPublicationYear "2020" @default.
• W3037972144 type Work @default.
• W3037972144 sameAs 3037972144 @default.
• W3037972144 citedByCount "2" @default.
• W3037972144 countsByYear W30379721442021 @default.
• W3037972144 countsByYear W30379721442023 @default.
• W3037972144 crossrefType "journal-article" @default.
• W3037972144 hasAuthorship W3037972144A5003580103 @default.
• W3037972144 hasAuthorship W3037972144A5020332409 @default.
• W3037972144 hasAuthorship W3037972144A5021237600 @default.
• W3037972144 hasAuthorship W3037972144A5037036377 @default.
• W3037972144 hasAuthorship W3037972144A5061488497 @default.
• W3037972144 hasAuthorship W3037972144A5063459637 @default.
• W3037972144 hasAuthorship W3037972144A5079061857 @default.
• W3037972144 hasAuthorship W3037972144A5081585606 @default.
• W3037972144 hasAuthorship W3037972144A5084888732 @default.
• W3037972144 hasBestOaLocation W30379721441 @default.
• W3037972144 hasConcept C104317684 @default.
• W3037972144 hasConcept C116675565 @default.
• W3037972144 hasConcept C159047783 @default.
• W3037972144 hasConcept C203014093 @default.
• W3037972144 hasConcept C2776460866 @default.
• W3037972144 hasConcept C2776986154 @default.
• W3037972144 hasConcept C2778750513 @default.
• W3037972144 hasConcept C2778877831 @default.
• W3037972144 hasConcept C2779802037 @default.
• W3037972144 hasConcept C2779910956 @default.
• W3037972144 hasConcept C2781065037 @default.
• W3037972144 hasConcept C2781367151 @default.
• W3037972144 hasConcept C49105822 @default.
• W3037972144 hasConcept C523546767 @default.
• W3037972144 hasConcept C54355233 @default.
• W3037972144 hasConcept C55493867 @default.
• W3037972144 hasConcept C61716771 @default.
• W3037972144 hasConcept C71924100 @default.
• W3037972144 hasConcept C86803240 @default.
• W3037972144 hasConcept C89423630 @default.
• W3037972144 hasConcept C90583042 @default.
• W3037972144 hasConcept C90924648 @default.
• W3037972144 hasConceptScore W3037972144C104317684 @default.
• W3037972144 hasConceptScore W3037972144C116675565 @default.
• W3037972144 hasConceptScore W3037972144C159047783 @default.
• W3037972144 hasConceptScore W3037972144C203014093 @default.
• W3037972144 hasConceptScore W3037972144C2776460866 @default.
• W3037972144 hasConceptScore W3037972144C2776986154 @default.
• W3037972144 hasConceptScore W3037972144C2778750513 @default.
• W3037972144 hasConceptScore W3037972144C2778877831 @default.
• W3037972144 hasConceptScore W3037972144C2779802037 @default.
• W3037972144 hasConceptScore W3037972144C2779910956 @default.
• W3037972144 hasConceptScore W3037972144C2781065037 @default.
• W3037972144 hasConceptScore W3037972144C2781367151 @default.
• W3037972144 hasConceptScore W3037972144C49105822 @default.
• W3037972144 hasConceptScore W3037972144C523546767 @default.
• W3037972144 hasConceptScore W3037972144C54355233 @default.
• W3037972144 hasConceptScore W3037972144C55493867 @default.
• W3037972144 hasConceptScore W3037972144C61716771 @default.
• W3037972144 hasConceptScore W3037972144C71924100 @default.
• W3037972144 hasConceptScore W3037972144C86803240 @default.
• W3037972144 hasConceptScore W3037972144C89423630 @default.
• W3037972144 hasConceptScore W3037972144C90583042 @default.
• W3037972144 hasConceptScore W3037972144C90924648 @default.
• W3037972144 hasFunder F4320321001 @default.
• W3037972144 hasLocation W30379721441 @default.

• next