Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037973721> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3037973721 endingPage "35" @default.
- W3037973721 startingPage "30" @default.
- W3037973721 abstract "Multiple myeloma (MM) is a malignancy of bone marrow plasma cells that produce abnormal immunoglobulins. It is the second most common hematologic cancer and typically is diagnosed in individuals ages 65 to 74 years. MM is the final stage in a continuum that starts with monoclonal gammopathies of undetermined significance (MGUS), a premalignant condition characterized by production of abnormal immunoglobulins. Patients with MGUS often are asymptomatic but can experience clinical manifestations such as recurrent infections. Standard care for patients with MGUS is monitoring for progression to MM, which occurs in approximately 1% of patients per year. Some patients experience an intermediate phase called smoldering multiple myeloma (SMM), characterized by higher levels of abnormal immunoglobulins and more plasma cells in the bone marrow. Most cases of SMM progress to MM over 15 years. MM has specific diagnostic criteria with defining clinical characteristics: hypercalcemia, renal insufficiency, anemia, and bone lesions (ie, CRAB criteria). MM management involves corticosteroids, chemotherapy, and autologous stem cell transplantation, as well as addressing complications including renal disease, hypercalcemia, bone disease, pain, hyperviscosity syndrome, infections, thromboembolic events, and anemia. MM is incurable. The survival time range of patients with newly diagnosed MM is 5 to 7 years." @default.
- W3037973721 created "2020-07-02" @default.
- W3037973721 creator A5086719949 @default.
- W3037973721 date "2020-06-01" @default.
- W3037973721 modified "2023-09-23" @default.
- W3037973721 title "Bone Tumors: Multiple Myeloma." @default.
- W3037973721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32573185" @default.
- W3037973721 hasPublicationYear "2020" @default.
- W3037973721 type Work @default.
- W3037973721 sameAs 3037973721 @default.
- W3037973721 citedByCount "0" @default.
- W3037973721 crossrefType "journal-article" @default.
- W3037973721 hasAuthorship W3037973721A5086719949 @default.
- W3037973721 hasConcept C121608353 @default.
- W3037973721 hasConcept C126322002 @default.
- W3037973721 hasConcept C142724271 @default.
- W3037973721 hasConcept C159654299 @default.
- W3037973721 hasConcept C163864487 @default.
- W3037973721 hasConcept C203014093 @default.
- W3037973721 hasConcept C2776364478 @default.
- W3037973721 hasConcept C2776907643 @default.
- W3037973721 hasConcept C2777250017 @default.
- W3037973721 hasConcept C2777910003 @default.
- W3037973721 hasConcept C2778248108 @default.
- W3037973721 hasConcept C2779399171 @default.
- W3037973721 hasConcept C2780007613 @default.
- W3037973721 hasConcept C542903549 @default.
- W3037973721 hasConcept C71924100 @default.
- W3037973721 hasConcept C90924648 @default.
- W3037973721 hasConceptScore W3037973721C121608353 @default.
- W3037973721 hasConceptScore W3037973721C126322002 @default.
- W3037973721 hasConceptScore W3037973721C142724271 @default.
- W3037973721 hasConceptScore W3037973721C159654299 @default.
- W3037973721 hasConceptScore W3037973721C163864487 @default.
- W3037973721 hasConceptScore W3037973721C203014093 @default.
- W3037973721 hasConceptScore W3037973721C2776364478 @default.
- W3037973721 hasConceptScore W3037973721C2776907643 @default.
- W3037973721 hasConceptScore W3037973721C2777250017 @default.
- W3037973721 hasConceptScore W3037973721C2777910003 @default.
- W3037973721 hasConceptScore W3037973721C2778248108 @default.
- W3037973721 hasConceptScore W3037973721C2779399171 @default.
- W3037973721 hasConceptScore W3037973721C2780007613 @default.
- W3037973721 hasConceptScore W3037973721C542903549 @default.
- W3037973721 hasConceptScore W3037973721C71924100 @default.
- W3037973721 hasConceptScore W3037973721C90924648 @default.
- W3037973721 hasLocation W30379737211 @default.
- W3037973721 hasOpenAccess W3037973721 @default.
- W3037973721 hasPrimaryLocation W30379737211 @default.
- W3037973721 hasRelatedWork W1971653835 @default.
- W3037973721 hasRelatedWork W1997787000 @default.
- W3037973721 hasRelatedWork W2020472919 @default.
- W3037973721 hasRelatedWork W2023756150 @default.
- W3037973721 hasRelatedWork W2147423551 @default.
- W3037973721 hasRelatedWork W2333239088 @default.
- W3037973721 hasRelatedWork W2551784955 @default.
- W3037973721 hasRelatedWork W2575122607 @default.
- W3037973721 hasRelatedWork W2794101941 @default.
- W3037973721 hasRelatedWork W2893011256 @default.
- W3037973721 hasVolume "493" @default.
- W3037973721 isParatext "false" @default.
- W3037973721 isRetracted "false" @default.
- W3037973721 magId "3037973721" @default.
- W3037973721 workType "article" @default.