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- W3037974438 abstract "Introduction Endogenous or exogenous (corticosteroid-induced) glucocorticoids (GCs) excess represents, together with diabetes, the most common cause of secondary osteoporosis.Areas covered We present a comprehensive overview about the pathophysiology, clinical management and treatment of GCs induced osteoporosis (GIOP). According to PRISMA guidelines, a literature search identifying articles about bone and GCs was done.Expert opinion Despite the progress over the years and the increase in therapeutic options, there still are controversial issues about the management of GIOP. These mainly include the failure of BMD or FRAX to completely account for the rapid increase in fracture risk of most GC-treated patients, the understanding about the independent contribution on bone fragility of the underlying disease requiring GCs therapy, and the necessity of clearer information about the anti-fracture efficacy and long term-safety of most therapeutic options. Moreover, there are no specific indications for the management of bone fragility in endogenous hypercortisolism. Notwithstanding the above limitations there is a general consensus to recommend an assessment of fracture risk in all individuals >40 years committed to receive (or continuing) high dose (>7.5 mg of prednisone equivalent) GCs for ≥3 months and in all patients with fragility fracture history." @default.
- W3037974438 created "2020-07-02" @default.
- W3037974438 creator A5038606710 @default.
- W3037974438 creator A5044241073 @default.
- W3037974438 creator A5048078483 @default.
- W3037974438 creator A5052576992 @default.
- W3037974438 creator A5084310173 @default.
- W3037974438 date "2020-06-25" @default.
- W3037974438 modified "2023-10-17" @default.
- W3037974438 title "Updates in epidemiology, pathophysiology and management strategies of glucocorticoid-induced osteoporosis" @default.
- W3037974438 cites W1882252905 @default.
- W3037974438 cites W1920107567 @default.
- W3037974438 cites W1968089570 @default.
- W3037974438 cites W1968771860 @default.
- W3037974438 cites W1972567404 @default.
- W3037974438 cites W1973361468 @default.
- W3037974438 cites W1974492515 @default.
- W3037974438 cites W1974923890 @default.
- W3037974438 cites W1978136096 @default.
- W3037974438 cites W1978630977 @default.
- W3037974438 cites W1981465641 @default.
- W3037974438 cites W1983211249 @default.
- W3037974438 cites W1983391342 @default.
- W3037974438 cites W1984126393 @default.
- W3037974438 cites W1985500418 @default.
- W3037974438 cites W1986227399 @default.
- W3037974438 cites W1986621723 @default.
- W3037974438 cites W1992310701 @default.
- W3037974438 cites W1998023570 @default.
- W3037974438 cites W1999466669 @default.
- W3037974438 cites W2007725108 @default.
- W3037974438 cites W2011629184 @default.
- W3037974438 cites W2012626745 @default.
- W3037974438 cites W2016745117 @default.
- W3037974438 cites W2032686039 @default.
- W3037974438 cites W2042007405 @default.
- W3037974438 cites W2044687155 @default.
- W3037974438 cites W2045947279 @default.
- W3037974438 cites W2047588903 @default.
- W3037974438 cites W2048730055 @default.
- W3037974438 cites W2048813529 @default.
- W3037974438 cites W2055035482 @default.
- W3037974438 cites W2061962280 @default.
- W3037974438 cites W2062859034 @default.
- W3037974438 cites W2067231661 @default.
- W3037974438 cites W2068496880 @default.
- W3037974438 cites W2080089180 @default.
- W3037974438 cites W2081432593 @default.
- W3037974438 cites W2093042015 @default.
- W3037974438 cites W2095703370 @default.
- W3037974438 cites W2095741166 @default.
- W3037974438 cites W2099152409 @default.
- W3037974438 cites W2105648357 @default.
- W3037974438 cites W2106145280 @default.
- W3037974438 cites W2107983044 @default.
- W3037974438 cites W2108501167 @default.
- W3037974438 cites W2112598441 @default.
- W3037974438 cites W2115647238 @default.
- W3037974438 cites W2116751183 @default.
- W3037974438 cites W2117334048 @default.
- W3037974438 cites W2118314343 @default.
- W3037974438 cites W2121919643 @default.
- W3037974438 cites W2125715886 @default.
- W3037974438 cites W2129631167 @default.
- W3037974438 cites W2134051746 @default.
- W3037974438 cites W2134460604 @default.
- W3037974438 cites W2134771935 @default.
- W3037974438 cites W2139785110 @default.
- W3037974438 cites W2140881331 @default.
- W3037974438 cites W2142008186 @default.
- W3037974438 cites W2142905664 @default.
- W3037974438 cites W2148244700 @default.
- W3037974438 cites W2152099215 @default.
- W3037974438 cites W2152174465 @default.
- W3037974438 cites W2153059487 @default.
- W3037974438 cites W2155487985 @default.
- W3037974438 cites W2157410452 @default.
- W3037974438 cites W2158719201 @default.
- W3037974438 cites W2160611282 @default.
- W3037974438 cites W2162124694 @default.
- W3037974438 cites W2164229113 @default.
- W3037974438 cites W2167048916 @default.
- W3037974438 cites W2169251377 @default.
- W3037974438 cites W2170680219 @default.
- W3037974438 cites W2213174366 @default.
- W3037974438 cites W2291850936 @default.
- W3037974438 cites W2294986745 @default.
- W3037974438 cites W2314674563 @default.
- W3037974438 cites W2335178464 @default.
- W3037974438 cites W2338308982 @default.
- W3037974438 cites W2341958510 @default.
- W3037974438 cites W2342793300 @default.
- W3037974438 cites W2346626128 @default.
- W3037974438 cites W2368834918 @default.
- W3037974438 cites W2414426861 @default.
- W3037974438 cites W2472423566 @default.
- W3037974438 cites W2473636610 @default.
- W3037974438 cites W2474471198 @default.