FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037975824> ?p ?o ?g. }

• W3037975824 abstract "A range of studies showed probiotics like Streptococcus oligofermentans and Limosilactobacillus reuteri to inhibit the cariogenic activity and survival of Streptococcus mutans, possibly via the production of substances like H2O2, reuterin, ammonia and organic acids. We aimed to assess the environment-specific mechanisms underlying this inhibition. We cultured L. reuteri and S. oligofermentans in various environments; minimal medium (MM), MM containing glucose (MM+Glu), glycerol (MM+Gly), lactic acid (MM+Lac), arginine (MM+Arg) and all four substances (MM+all) in vitro. Culture supernatants were obtained and metabolite concentrations (reuterin, ammonia, H2O2, lactate) measured. S. mutans was similarly cultivated in the above six different MM variation media, with glucose being additionally added to the MM+Gly, MM+Lac, and MM+Arg group, with (test groups) and without (control groups) the addition of the supernatants of the described probiotic cultures. Lactate production by S. mutans was measured and its survival (as colony-forming-units/mL) assessed. L. reuteri environment-specifically produced reuterin, H2O2, ammonia and lactate, as did S. oligofermentans. When cultured in S. oligofermentans supernatants, lactate production by S. mutans was significantly reduced (p<0.01), especially in MM+Lac+Glu and MM+all, with no detectable lactate production at all (controls means±SD: 4.46±0.41mM and 6.00±0.29 mM, respectively, p<0.001). A similar reduction in lactate production was found when S. mutans was cultured in L. reuteri supernatants (p<0.05) for all groups except MM+Lac+Glu. Survival of S. mutans cultured in S. oligofermentans supernatants in MM+Lac+Glu and MM+all was significantly reduced by 0.6-log10 and 0.5-log10, respectively. Treatment with the supernatant of L. reuteri resulted in a reduction in the viability of S. mutans in MM+Gly+Glu and MM+all by 6.1-log10 and 7.1-log10, respectively. Probiotic effects on the metabolic activity and survival of S. mutans were environment-specific through different pathways." @default.
• W3037975824 created "2020-07-02" @default.
• W3037975824 creator A5056297923 @default.
• W3037975824 creator A5058001588 @default.
• W3037975824 creator A5063934370 @default.
• W3037975824 date "2020-06-26" @default.
• W3037975824 modified "2023-10-05" @default.
• W3037975824 title "Environment-Specific Probiotic Supernatants Modify the Metabolic Activity and Survival of Streptococcus mutans in vitro" @default.
• W3037975824 cites W1514542940 @default.
• W3037975824 cites W1552861722 @default.
• W3037975824 cites W1561959808 @default.
• W3037975824 cites W1884485208 @default.
• W3037975824 cites W1950060995 @default.
• W3037975824 cites W1967665214 @default.
• W3037975824 cites W1968577348 @default.
• W3037975824 cites W1978121928 @default.
• W3037975824 cites W1984545633 @default.
• W3037975824 cites W1998827818 @default.
• W3037975824 cites W1999920042 @default.
• W3037975824 cites W2004069390 @default.
• W3037975824 cites W2013990754 @default.
• W3037975824 cites W2015022194 @default.
• W3037975824 cites W2031072116 @default.
• W3037975824 cites W2045073869 @default.
• W3037975824 cites W2051909929 @default.
• W3037975824 cites W2053014314 @default.
• W3037975824 cites W2059518641 @default.
• W3037975824 cites W2073395843 @default.
• W3037975824 cites W2073995852 @default.
• W3037975824 cites W2075560828 @default.
• W3037975824 cites W2080223747 @default.
• W3037975824 cites W2083392938 @default.
• W3037975824 cites W2095566926 @default.
• W3037975824 cites W2100148691 @default.
• W3037975824 cites W2109833361 @default.
• W3037975824 cites W2113534020 @default.
• W3037975824 cites W2135517360 @default.
• W3037975824 cites W2146681091 @default.
• W3037975824 cites W2148070607 @default.
• W3037975824 cites W2150981918 @default.
• W3037975824 cites W2156053584 @default.
• W3037975824 cites W2296180810 @default.
• W3037975824 cites W2512842904 @default.
• W3037975824 cites W2523457784 @default.
• W3037975824 cites W2555606342 @default.
• W3037975824 cites W2581187823 @default.
• W3037975824 cites W2753642535 @default.
• W3037975824 cites W2756519936 @default.
• W3037975824 cites W2793586044 @default.
• W3037975824 cites W2795389370 @default.
• W3037975824 cites W2883703760 @default.
• W3037975824 cites W2926246286 @default.
• W3037975824 cites W2941445486 @default.
• W3037975824 cites W2972034319 @default.
• W3037975824 cites W2989208992 @default.
• W3037975824 cites W3011890245 @default.
• W3037975824 cites W3016016792 @default.
• W3037975824 cites W4238871407 @default.
• W3037975824 doi "https://doi.org/10.3389/fmicb.2020.01447" @default.
• W3037975824 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7332556" @default.
• W3037975824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32670254" @default.
• W3037975824 hasPublicationYear "2020" @default.
• W3037975824 type Work @default.
• W3037975824 sameAs 3037975824 @default.
• W3037975824 citedByCount "8" @default.
• W3037975824 countsByYear W30379758242020 @default.
• W3037975824 countsByYear W30379758242021 @default.
• W3037975824 countsByYear W30379758242022 @default.
• W3037975824 countsByYear W30379758242023 @default.
• W3037975824 crossrefType "journal-article" @default.
• W3037975824 hasAuthorship W3037975824A5056297923 @default.
• W3037975824 hasAuthorship W3037975824A5058001588 @default.
• W3037975824 hasAuthorship W3037975824A5063934370 @default.
• W3037975824 hasBestOaLocation W30379758241 @default.
• W3037975824 hasConcept C185592680 @default.
• W3037975824 hasConcept C192285135 @default.
• W3037975824 hasConcept C202751555 @default.
• W3037975824 hasConcept C2775898472 @default.
• W3037975824 hasConcept C2775920511 @default.
• W3037975824 hasConcept C2778430296 @default.
• W3037975824 hasConcept C2780255968 @default.
• W3037975824 hasConcept C2780881558 @default.
• W3037975824 hasConcept C523546767 @default.
• W3037975824 hasConcept C54355233 @default.
• W3037975824 hasConcept C55493867 @default.
• W3037975824 hasConcept C86803240 @default.
• W3037975824 hasConcept C89423630 @default.
• W3037975824 hasConceptScore W3037975824C185592680 @default.
• W3037975824 hasConceptScore W3037975824C192285135 @default.
• W3037975824 hasConceptScore W3037975824C202751555 @default.
• W3037975824 hasConceptScore W3037975824C2775898472 @default.
• W3037975824 hasConceptScore W3037975824C2775920511 @default.
• W3037975824 hasConceptScore W3037975824C2778430296 @default.
• W3037975824 hasConceptScore W3037975824C2780255968 @default.
• W3037975824 hasConceptScore W3037975824C2780881558 @default.
• W3037975824 hasConceptScore W3037975824C523546767 @default.
• W3037975824 hasConceptScore W3037975824C54355233 @default.
• W3037975824 hasConceptScore W3037975824C55493867 @default.
• W3037975824 hasConceptScore W3037975824C86803240 @default.
• W3037975824 hasConceptScore W3037975824C89423630 @default.

• next