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• W3038085304 abstract "Livestock breeding has shifted during the past decade toward genomic selection. For the estimation of breeding values in purebred breeding schemes, genomic best linear unbiased prediction has become the method of choice. Systematic crossbreeding with the aim to utilize heterosis and breed complementary effects is widely used in livestock breeding, especially in pig and poultry breeding. The goal is to improve the performance of the crossbred animals. Due to genotype-by-environment interactions, imperfect linkage disequilibrium, and the existence of dominance and imprinting, purebred and crossbred performances are not perfectly correlated. Hence, more complex genomic models are required for crossbred populations. This study reviews and compares such models. Compared to purebred genomic models, the reviewed models were of much higher complexity due to the inclusion of dominance effects, breed-specific effects, imprinting effects, and the joint evaluation of purebred and crossbred performance data. With the model assessment work conducted until now, it is not possible to come to a clear recommendation as to which existing method is most suitable for a specific breeding program and a specific genetic trait architecture. Since it is expected that a superior method includes all the different genetic effects in a single model, a dominance model with imprinting and breed-specific SNP effects is proposed. Further progress could be made by assuming realistic covariance structures between the genetic effects of the different breeding lines, and by using larger marker panels and mixture distributions for the SNP effects." @default.
• W3038085304 created "2020-07-02" @default.
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• W3038085304 date "2020-06-26" @default.
• W3038085304 modified "2023-10-01" @default.
• W3038085304 title "A Review of Genomic Models for the Analysis of Livestock Crossbred Data" @default.
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• W3038085304 doi "https://doi.org/10.3389/fgene.2020.00568" @default.
• W3038085304 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7332767" @default.
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