Matches in SemOpenAlex for { <https://semopenalex.org/work/W3038454984> ?p ?o ?g. }
- W3038454984 abstract "Aim To determine the mitochondrial microsatellite instability (mtMSI) status in a series of Malaysian patients with brain tumors. Furthermore, we analyzed whether the mtMSI status is associated with the clinicopathological features of the patients. Material and methods Forty fresh frozen tumor tissues along with blood samples of brain tumor patients were analyzed for mtMSI by PCR amplification of genomic DNAs, and the amplicons were directly sequenced in both directions using Sanger sequencing. Results Microsatellite analysis revealed that 20% (8 out of 40) of the tumors were mtMSI positive with a total of 8 mtMSI changes. All mtMSI markers were detected in D310 and D16184 of the D-loop region. Additionally, no significant association was observed between mtMSI status and clinicopathological features. Conclusion The variations, specifically the mtMSI, suggest that the mitochondrial DNA (mtDNA) can be targeted for genomic alteration in brain tumors. Therefore, the specific role of mtDNA alteration in brain tumor development and prognosis requires further investigation." @default.
- W3038454984 created "2020-07-10" @default.
- W3038454984 creator A5037814514 @default.
- W3038454984 creator A5050112900 @default.
- W3038454984 creator A5062715021 @default.
- W3038454984 creator A5069557885 @default.
- W3038454984 creator A5070998542 @default.
- W3038454984 date "2020-01-01" @default.
- W3038454984 modified "2023-09-25" @default.
- W3038454984 title "Accumulation of mitochondrial dna microsatellite instability in malaysian patients with primary central nervous system tumors" @default.
- W3038454984 cites W1530093870 @default.
- W3038454984 cites W1546375972 @default.
- W3038454984 cites W1613291744 @default.
- W3038454984 cites W1626428648 @default.
- W3038454984 cites W164701562 @default.
- W3038454984 cites W1704572801 @default.
- W3038454984 cites W1963638866 @default.
- W3038454984 cites W1975724024 @default.
- W3038454984 cites W1983384175 @default.
- W3038454984 cites W1985915691 @default.
- W3038454984 cites W1995819860 @default.
- W3038454984 cites W1998166655 @default.
- W3038454984 cites W1998344938 @default.
- W3038454984 cites W2018185503 @default.
- W3038454984 cites W2019468268 @default.
- W3038454984 cites W2020286448 @default.
- W3038454984 cites W2036140173 @default.
- W3038454984 cites W2046928699 @default.
- W3038454984 cites W2052703170 @default.
- W3038454984 cites W2064879869 @default.
- W3038454984 cites W2084897884 @default.
- W3038454984 cites W2105121562 @default.
- W3038454984 cites W2107639379 @default.
- W3038454984 cites W2109291482 @default.
- W3038454984 cites W2109876844 @default.
- W3038454984 cites W2112421940 @default.
- W3038454984 cites W2145795805 @default.
- W3038454984 cites W2154546296 @default.
- W3038454984 cites W2154629777 @default.
- W3038454984 cites W2155429665 @default.
- W3038454984 cites W2158685619 @default.
- W3038454984 cites W2163858303 @default.
- W3038454984 cites W2166972467 @default.
- W3038454984 cites W2170818431 @default.
- W3038454984 cites W2193967519 @default.
- W3038454984 cites W2341428761 @default.
- W3038454984 cites W2604001476 @default.
- W3038454984 cites W2746633820 @default.
- W3038454984 cites W2781942722 @default.
- W3038454984 cites W2799431053 @default.
- W3038454984 cites W2799902256 @default.
- W3038454984 cites W2804473310 @default.
- W3038454984 cites W2895139507 @default.
- W3038454984 cites W2903815725 @default.
- W3038454984 cites W2904441722 @default.
- W3038454984 cites W2913576084 @default.
- W3038454984 cites W2983579966 @default.
- W3038454984 doi "https://doi.org/10.5137/1019-5149.jtn.27893-20.4" @default.
- W3038454984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33491172" @default.
- W3038454984 hasPublicationYear "2020" @default.
- W3038454984 type Work @default.
- W3038454984 sameAs 3038454984 @default.
- W3038454984 citedByCount "3" @default.
- W3038454984 countsByYear W30384549842021 @default.
- W3038454984 countsByYear W30384549842022 @default.
- W3038454984 crossrefType "journal-article" @default.
- W3038454984 hasAuthorship W3038454984A5037814514 @default.
- W3038454984 hasAuthorship W3038454984A5050112900 @default.
- W3038454984 hasAuthorship W3038454984A5062715021 @default.
- W3038454984 hasAuthorship W3038454984A5069557885 @default.
- W3038454984 hasAuthorship W3038454984A5070998542 @default.
- W3038454984 hasBestOaLocation W30384549841 @default.
- W3038454984 hasConcept C104317684 @default.
- W3038454984 hasConcept C126322002 @default.
- W3038454984 hasConcept C142724271 @default.
- W3038454984 hasConcept C17757408 @default.
- W3038454984 hasConcept C180754005 @default.
- W3038454984 hasConcept C24586158 @default.
- W3038454984 hasConcept C2779130545 @default.
- W3038454984 hasConcept C2779767149 @default.
- W3038454984 hasConcept C49105822 @default.
- W3038454984 hasConcept C502942594 @default.
- W3038454984 hasConcept C51679486 @default.
- W3038454984 hasConcept C529278444 @default.
- W3038454984 hasConcept C54355233 @default.
- W3038454984 hasConcept C552990157 @default.
- W3038454984 hasConcept C61320498 @default.
- W3038454984 hasConcept C71924100 @default.
- W3038454984 hasConcept C76818968 @default.
- W3038454984 hasConcept C8185291 @default.
- W3038454984 hasConcept C86803240 @default.
- W3038454984 hasConceptScore W3038454984C104317684 @default.
- W3038454984 hasConceptScore W3038454984C126322002 @default.
- W3038454984 hasConceptScore W3038454984C142724271 @default.
- W3038454984 hasConceptScore W3038454984C17757408 @default.
- W3038454984 hasConceptScore W3038454984C180754005 @default.
- W3038454984 hasConceptScore W3038454984C24586158 @default.
- W3038454984 hasConceptScore W3038454984C2779130545 @default.
- W3038454984 hasConceptScore W3038454984C2779767149 @default.
- W3038454984 hasConceptScore W3038454984C49105822 @default.