Matches in SemOpenAlex for { <https://semopenalex.org/work/W3038525021> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3038525021 endingPage "92" @default.
- W3038525021 startingPage "89" @default.
- W3038525021 abstract "Objectives: Status epilepticus (SE) is associated with high morbidity and mortality. The American Epilepsy Society (AES) has established guidelines regarding proper dosing of antiepileptic drugs (AEDs). There are also recommendations for appropriate weaning off anesthetic agents in SE. Our aim was to determine the frequency with which guidelines were being followed during routine clinical care. Methods: A retrospective chart review was completed for patients with a diagnosis of SE within the last 10 years. All patients with SE on anesthetic agents were included when analyzing AED dosing. Patients with anoxic brain injury were excluded when reviewing anesthetic wean times. Results: Seventy-six patients were identified on anesthetic agents. Five patients had anoxic brain injury and were excluded from the anesthetic weaning analysis. Medications were under dosed as follows: lorazepam 0.05 mg/kg (N=51), midazolam 0.07 mg/kg (N=14), fosphenytoin 17.9 mg/kg (N=47), levetiracetam 21.7 mg/kg (N=42), valproate sodium 16.7 mg/kg (N=12), phenobarbital 4.1 mg/kg (N=4), lacosamide 215 mg (N=13), and topiramate 333 mg (N=3). Anesthetic agents were weaned as follows: <24 hours 32/71 (45%), 24 to 48 hours 11/71 (15%), 48 to 72 hours 12/71 (17%), and >72 hours 11/71 (15%). Seizure recurrence rates were: 8/32 (25%) <24 hours, 2/11 (18%) 24 to 48 hours, 1/12 (8.3%) 48 to 72 hours, and 1/11 (9%) at >72 hours. Conclusions: This retrospective review demonstrates how guidelines and recommendations for SE are not consistently followed. Under dosing of AEDs and aggressive weaning of anesthetic agents may result in higher morbidity and mortality." @default.
- W3038525021 created "2020-07-10" @default.
- W3038525021 creator A5000873877 @default.
- W3038525021 creator A5016665344 @default.
- W3038525021 creator A5078548284 @default.
- W3038525021 date "2020-07-01" @default.
- W3038525021 modified "2023-10-14" @default.
- W3038525021 title "Treatment of Status Epilepticus" @default.
- W3038525021 cites W1994421931 @default.
- W3038525021 cites W2029569324 @default.
- W3038525021 cites W2056821940 @default.
- W3038525021 cites W2252496421 @default.
- W3038525021 cites W2592671116 @default.
- W3038525021 cites W2610306386 @default.
- W3038525021 cites W2754799110 @default.
- W3038525021 cites W2757596741 @default.
- W3038525021 cites W2799984727 @default.
- W3038525021 cites W2800508851 @default.
- W3038525021 cites W2908577296 @default.
- W3038525021 cites W2938118100 @default.
- W3038525021 cites W2991266411 @default.
- W3038525021 doi "https://doi.org/10.1097/nrl.0000000000000281" @default.
- W3038525021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32618836" @default.
- W3038525021 hasPublicationYear "2020" @default.
- W3038525021 type Work @default.
- W3038525021 sameAs 3038525021 @default.
- W3038525021 citedByCount "3" @default.
- W3038525021 countsByYear W30385250212022 @default.
- W3038525021 countsByYear W30385250212023 @default.
- W3038525021 crossrefType "journal-article" @default.
- W3038525021 hasAuthorship W3038525021A5000873877 @default.
- W3038525021 hasAuthorship W3038525021A5016665344 @default.
- W3038525021 hasAuthorship W3038525021A5078548284 @default.
- W3038525021 hasConcept C118552586 @default.
- W3038525021 hasConcept C126322002 @default.
- W3038525021 hasConcept C141071460 @default.
- W3038525021 hasConcept C167135981 @default.
- W3038525021 hasConcept C2776814716 @default.
- W3038525021 hasConcept C2777288759 @default.
- W3038525021 hasConcept C2777332695 @default.
- W3038525021 hasConcept C2777341932 @default.
- W3038525021 hasConcept C2777683783 @default.
- W3038525021 hasConcept C2778000748 @default.
- W3038525021 hasConcept C2778139780 @default.
- W3038525021 hasConcept C2778162923 @default.
- W3038525021 hasConcept C2778186239 @default.
- W3038525021 hasConcept C2780651394 @default.
- W3038525021 hasConcept C2781453256 @default.
- W3038525021 hasConcept C42219234 @default.
- W3038525021 hasConcept C71924100 @default.
- W3038525021 hasConceptScore W3038525021C118552586 @default.
- W3038525021 hasConceptScore W3038525021C126322002 @default.
- W3038525021 hasConceptScore W3038525021C141071460 @default.
- W3038525021 hasConceptScore W3038525021C167135981 @default.
- W3038525021 hasConceptScore W3038525021C2776814716 @default.
- W3038525021 hasConceptScore W3038525021C2777288759 @default.
- W3038525021 hasConceptScore W3038525021C2777332695 @default.
- W3038525021 hasConceptScore W3038525021C2777341932 @default.
- W3038525021 hasConceptScore W3038525021C2777683783 @default.
- W3038525021 hasConceptScore W3038525021C2778000748 @default.
- W3038525021 hasConceptScore W3038525021C2778139780 @default.
- W3038525021 hasConceptScore W3038525021C2778162923 @default.
- W3038525021 hasConceptScore W3038525021C2778186239 @default.
- W3038525021 hasConceptScore W3038525021C2780651394 @default.
- W3038525021 hasConceptScore W3038525021C2781453256 @default.
- W3038525021 hasConceptScore W3038525021C42219234 @default.
- W3038525021 hasConceptScore W3038525021C71924100 @default.
- W3038525021 hasIssue "4" @default.
- W3038525021 hasLocation W30385250211 @default.
- W3038525021 hasOpenAccess W3038525021 @default.
- W3038525021 hasPrimaryLocation W30385250211 @default.
- W3038525021 hasRelatedWork W1978839222 @default.
- W3038525021 hasRelatedWork W2000487802 @default.
- W3038525021 hasRelatedWork W2088094355 @default.
- W3038525021 hasRelatedWork W2144478277 @default.
- W3038525021 hasRelatedWork W2153737883 @default.
- W3038525021 hasRelatedWork W2592415504 @default.
- W3038525021 hasRelatedWork W2842035673 @default.
- W3038525021 hasRelatedWork W3002439210 @default.
- W3038525021 hasRelatedWork W3038525021 @default.
- W3038525021 hasRelatedWork W2290076654 @default.
- W3038525021 hasVolume "25" @default.
- W3038525021 isParatext "false" @default.
- W3038525021 isRetracted "false" @default.
- W3038525021 magId "3038525021" @default.
- W3038525021 workType "article" @default.