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- W3038632844 abstract "ABSTRACT We describe here the design and implementation of an in-vitro BBB-on-a-chip open model system capable of reconstituting the microenvironment of the blood brain barrier. This system allows controlled unidirectional flow of nutrients and biologicals on the lumen of the artificial microvessel. This BBB-on-a-chip is suitable for high resolution electron microscopy and it is amenable for quantitative 3D live fluorescence imaging using spinning confocal disk or lattice light sheet microscopy (LLSM) to follow, for example the transcytosis across the BBB-like barrier of fluorescently-tagged biological, viruses or nanoparticles." @default.
- W3038632844 created "2020-07-10" @default.
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- W3038632844 date "2020-07-01" @default.
- W3038632844 modified "2023-09-23" @default.
- W3038632844 title "An<i>in-vitro</i>BBB-on-a-chip open model of human blood-brain barrier enabling advanced optical imaging" @default.
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- W3038632844 doi "https://doi.org/10.1101/2020.06.30.175380" @default.
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