Matches in SemOpenAlex for { <https://semopenalex.org/work/W3038724177> ?p ?o ?g. }
- W3038724177 endingPage "730" @default.
- W3038724177 startingPage "730" @default.
- W3038724177 abstract "Zonula occludens toxin (Zot) is a conserved protein in filamentous vibriophages and has been reported as a putative toxin in Vibrio cholerae. Recently, widespread distribution of zot-encoding prophages was found among marine Vibrio species, including environmental isolates. However, little is known about the dynamics of these prophages beyond V. cholerae. In this study, we characterized and quantified the zot-encoding filamentous phage VAIϕ, spontaneously induced from the fish pathogen V. anguillarum. VAIϕ contained 6117 bp encoding 11 ORFs, including ORF8pVAI, exhibiting 27%–73% amino acid identity to Inovirus Zot-like proteins. A qPCR method revealed an average of four VAIϕ genomes per host genome during host exponential growth phase, and PCR demonstrated dissemination of induced VAIϕ to other V. anguillarum strains through re-integration in non-lysogens. VAIϕ integrated into both chromosomes of V. anguillarum by recombination, causing changes in a putative ORF in the phage genome. Phylogenetic analysis of the V. anguillarum Inoviridae elements revealed mosaic genome structures related to mainly V. cholerae. Altogether, this study contributes to the understanding of Inovirus infection dynamics and mobilization of zot-like genes beyond human pathogenic vibrios, and discusses their potential role in the evolution of the fish pathogen V. anguillarum." @default.
- W3038724177 created "2020-07-10" @default.
- W3038724177 creator A5006995861 @default.
- W3038724177 creator A5007264189 @default.
- W3038724177 creator A5018156686 @default.
- W3038724177 creator A5046183873 @default.
- W3038724177 creator A5056657332 @default.
- W3038724177 date "2020-07-06" @default.
- W3038724177 modified "2023-10-18" @default.
- W3038724177 title "Beyond Cholera: Characterization of zot-Encoding Filamentous Phages in the Marine Fish Pathogen Vibrio anguillarum" @default.
- W3038724177 cites W1520328007 @default.
- W3038724177 cites W1585873861 @default.
- W3038724177 cites W1894075467 @default.
- W3038724177 cites W1894909642 @default.
- W3038724177 cites W1972267834 @default.
- W3038724177 cites W1977062683 @default.
- W3038724177 cites W1977151336 @default.
- W3038724177 cites W1977648667 @default.
- W3038724177 cites W1979502589 @default.
- W3038724177 cites W1982519372 @default.
- W3038724177 cites W1984445465 @default.
- W3038724177 cites W1988994342 @default.
- W3038724177 cites W1991330646 @default.
- W3038724177 cites W2020103148 @default.
- W3038724177 cites W2026679988 @default.
- W3038724177 cites W2028857164 @default.
- W3038724177 cites W2033702989 @default.
- W3038724177 cites W2042220177 @default.
- W3038724177 cites W2045162565 @default.
- W3038724177 cites W2053100044 @default.
- W3038724177 cites W2056169693 @default.
- W3038724177 cites W2057754366 @default.
- W3038724177 cites W2061583677 @default.
- W3038724177 cites W2075005352 @default.
- W3038724177 cites W2079946180 @default.
- W3038724177 cites W2080410350 @default.
- W3038724177 cites W2084235692 @default.
- W3038724177 cites W2089015524 @default.
- W3038724177 cites W2094201044 @default.
- W3038724177 cites W2094258611 @default.
- W3038724177 cites W2104387858 @default.
- W3038724177 cites W2109590782 @default.
- W3038724177 cites W2110815718 @default.
- W3038724177 cites W2114049512 @default.
- W3038724177 cites W2114570899 @default.
- W3038724177 cites W2120137321 @default.
- W3038724177 cites W2124088653 @default.
- W3038724177 cites W2126259583 @default.
- W3038724177 cites W2126550926 @default.
- W3038724177 cites W2127506846 @default.
- W3038724177 cites W2129983297 @default.
- W3038724177 cites W2138502991 @default.
- W3038724177 cites W2139857020 @default.
- W3038724177 cites W2140861554 @default.
- W3038724177 cites W2151070144 @default.
- W3038724177 cites W2152770371 @default.
- W3038724177 cites W2153793431 @default.
- W3038724177 cites W2157086852 @default.
- W3038724177 cites W2162792752 @default.
- W3038724177 cites W2171069185 @default.
- W3038724177 cites W2255797180 @default.
- W3038724177 cites W2311088209 @default.
- W3038724177 cites W2346529406 @default.
- W3038724177 cites W2520122574 @default.
- W3038724177 cites W2524195063 @default.
- W3038724177 cites W2583179310 @default.
- W3038724177 cites W2594708657 @default.
- W3038724177 cites W2736238444 @default.
- W3038724177 cites W2777621405 @default.
- W3038724177 cites W2791869850 @default.
- W3038724177 cites W2810340995 @default.
- W3038724177 cites W2909215978 @default.
- W3038724177 cites W2922784940 @default.
- W3038724177 cites W2930497553 @default.
- W3038724177 cites W2963011827 @default.
- W3038724177 cites W3008405029 @default.
- W3038724177 cites W4231252759 @default.
- W3038724177 cites W4249233175 @default.
- W3038724177 doi "https://doi.org/10.3390/v12070730" @default.
- W3038724177 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7412436" @default.
- W3038724177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32640584" @default.
- W3038724177 hasPublicationYear "2020" @default.
- W3038724177 type Work @default.
- W3038724177 sameAs 3038724177 @default.
- W3038724177 citedByCount "14" @default.
- W3038724177 countsByYear W30387241772020 @default.
- W3038724177 countsByYear W30387241772021 @default.
- W3038724177 countsByYear W30387241772022 @default.
- W3038724177 countsByYear W30387241772023 @default.
- W3038724177 crossrefType "journal-article" @default.
- W3038724177 hasAuthorship W3038724177A5006995861 @default.
- W3038724177 hasAuthorship W3038724177A5007264189 @default.
- W3038724177 hasAuthorship W3038724177A5018156686 @default.
- W3038724177 hasAuthorship W3038724177A5046183873 @default.
- W3038724177 hasAuthorship W3038724177A5056657332 @default.
- W3038724177 hasBestOaLocation W30387241771 @default.
- W3038724177 hasConcept C104317684 @default.
- W3038724177 hasConcept C141231307 @default.