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• W3038997989 endingPage "1759720X2093605" @default.
• W3038997989 startingPage "1759720X2093605" @default.
• W3038997989 abstract "Currently, there is a growing interest in Janus kinase (JAK) intracellular signalling since targeted inhibitors against these pathways are proving effective in the treatment of a range of immune-mediated diseases, such as rheumatoid arthritis (RA), psoriasis, psoriatic arthritis (PsA), inflammatory bowel disease and atopic dermatitis. In particular, post marketing experience and the increasing development of new pharmacological inhibitors of broad and increasingly selective JAK pathways provide new insights into the JAK pathway role in viral infections as well as their pathogenic role in immune-mediated inflammatory diseases. Herein we provide an overview of the biological role of JAK signalling and its role in immunity against viruses, with particular regard to herpes zoster reactivation. Thereafter, we will discuss the evidence currently available on the principal JAK inhibitors and their association with viral infections." @default.
• W3038997989 created "2020-07-10" @default.
• W3038997989 creator A5035130926 @default.
• W3038997989 creator A5056428016 @default.
• W3038997989 creator A5071482630 @default.
• W3038997989 date "2020-01-01" @default.
• W3038997989 modified "2023-10-16" @default.
• W3038997989 title "JAK inhibitors and infections risk: focus on herpes zoster" @default.
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