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• W3039046000 abstract "Prevalence of overweight and obesity, a condition that promotes development of chronic degenerative diseases, has increased in Mexico in recent years. Implementation of strategies to increase daily consumption of vegetables, legumes, whole grain cereals, and fruits by the population will result in an adequate intake of soluble fiber, antioxidants, protein of vegetable origin, and vitamins. To assess the effect of a commercial food product prepared using 6 legumes on some anthropometric and biochemical parameters in apparently healthy subjects. A randomised dietary intervention trial where subjects in the study group received for three months 15 g of the product, administered daily in periods of five days with two days of rest. Before and after intervention, anthropometric and dietary assessments were performed, and serum glucose, lipid profile, insulin, ultrasensitive C-reactive protein, malondialdehyde (MDA) and insulin resistance (HOMA index) were measured. A Mann-Whitney U test was used and values of P < .05 were considered statistically significant. Sixty university students were included in the study (53% males). At the end of the intervention, decreases were seen in serum glucose levels (P = .001), MDA (P = .001) and HOMA index (P = .017), but there were no significant changes in all other parameters. Daily intake of 15 g of the legume-based food product improved serum glucose and malondialdehyde levels in the study group, as well as insulin resistance; which could be attributed to the presence of polyphenols and isoflavones such as genistein in legumes. En México, en los últimos años se ha incrementado la prevalencia de sobrepeso y obesidad, condición que favorece el desarrollo de enfermedades crónico-degenerativas. Implementar estrategias para incrementar en la población el consumo diario de vegetales, leguminosas, cereales de grano entero y frutas, implicará una ingesta adecuada de fibra soluble, antioxidantes, proteínas de origen vegetal y vitaminas. Evaluar el efecto de un producto alimenticio comercial elaborado a base de 6 leguminosas sobre determinados parámetros antropométricos y bioquímicos en sujetos sanos. Ensayo aleatorizado de intervención dietética, en el que los sujetos del grupo de estudio recibieron durante tres meses, 15 g del producto, administrados diariamente en periodos de cinco días con dos días de descanso. Antes y después de la intervención se realizó una valoración antropométrica y dietética, así como una cuantificación sérica de glucosa, perfil de lípidos, insulina, proteína C reactiva ultrasensible, malondialdehído (MDA) y resistencia a la insulina (índice HOMA). Se utilizó la prueba U de Mann Whitney y una significación estadística de P < 0,05. Se incluyeron 60 estudiantes universitarios (53% hombres). Al término de la intervención, en el grupo de estudio se obtuvo una disminución en los niveles séricos de glucosa (P = 0,001), MDA (P = 0,001) e índice HOMA (P = 0,017), sin cambios significativos en el resto de los parámetros. La ingesta diaria de 15 g de un producto a base de leguminosas mejoró en el grupo estudiado los niveles séricos de glucosa y malondialdehído, así como la resistencia a la insulina; lo cual podría atribuirse al contenido de polifenoles e isoflavonas como la genisteína presentes en las leguminosas." @default.
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• W3039046000 date "2020-04-01" @default.
• W3039046000 modified "2023-10-18" @default.
• W3039046000 title "Effect of dietary intervention with a legume-based food product on malondialdehyde levels, HOMA index, and lipid profile" @default.
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• W3039046000 doi "https://doi.org/10.1016/j.endien.2019.08.007" @default.
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