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- W3039091279 abstract "The chemical conversion films from deep eutectic solvents (DESs) have recently been shown to reduce the corrosion rate of magnesium alloys, which are recognized as a kind of promising materials applied in the human body. However, the biocompatibility of the conversion films has not been investigated. This study proposes an uncommon DES system composed of lithium chloride and urea to fabricate the chemical conversion films on Mg and its alloy. The fabrication process of the conversion film is facile, which is performed by the heat treatment of the substrate in the DES at about 200 °C for 30 min. It is found that the thermal decomposition of the DES can release hydrogen, which diffuses into the Mg substrate to form MgH2-based conversion films. The DES conversion film possesses a porous structure on pure Mg, whereas it becomes dense on the alloy with some cracks. X-ray photoelectron spectroscopy shows that MgCO3 and oxides also exist in the DES conversion films, which depends on the substrate. Electrochemical corrosion test and in vitro biocompatibility tests, including hemolysis, cytotoxicity, antibacterial, and cytoskeleton staining experiments, are performed in a simulated body environment, which shows that the corrosion resistance and biocompatibility of the substrates have been improved significantly. We expect that the DES heat treatment method will be applied to the fabrication of corrosion-resistant and biocompatible surfaces for biodegradable Mg alloys." @default.
- W3039091279 created "2020-07-10" @default.
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- W3039091279 date "2020-07-03" @default.
- W3039091279 modified "2023-10-17" @default.
- W3039091279 title "Formation and<i>In Vitro</i>Evaluation of a Deep Eutectic Solvent Conversion Film on Biodegradable Magnesium Alloy" @default.
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- W3039091279 doi "https://doi.org/10.1021/acsami.0c10992" @default.
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