Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039143487> ?p ?o ?g. }
- W3039143487 endingPage "2131" @default.
- W3039143487 startingPage "2121" @default.
- W3039143487 abstract "The complement system is a vital component of the innate immune system, though its role in bacteremia is poorly understood. We present complement levels in Staphylococcus aureus bacteremia (SAB) and Gram-negative bacteremia (GNB) and describe observed associations of complement levels with clinical outcomes. Complement and cytokine levels were measured in serum samples from 20 hospitalized patients with SAB, 20 hospitalized patients with GNB, 10 non-infected hospitalized patients, and 10 community controls. C5a levels were significantly higher in patients with SAB as compared to patients with GNB. Low C4 and C3 levels were associated with septic shock and 30-day mortality in patients with GNB, and elevated C3 was associated with a desirable outcome defined as absence of (1) septic shock, (2) acute renal failure, and (3) death within 30 days of bacteremia. Low levels of C9 were associated with septic shock in patients with GNB but not SAB. Elevated IL-10 was associated with increased 30-day mortality in patients with SAB. Complement profiles differ in patients with SAB and those with GNB. Measurement of IL-10 in patients with SAB and of C4, C3, and C9 in patients with GNB may help to identify those at higher risk for poor outcomes." @default.
- W3039143487 created "2020-07-10" @default.
- W3039143487 creator A5011455639 @default.
- W3039143487 creator A5020327284 @default.
- W3039143487 creator A5036121557 @default.
- W3039143487 creator A5039854274 @default.
- W3039143487 creator A5045500368 @default.
- W3039143487 creator A5048740503 @default.
- W3039143487 creator A5079680275 @default.
- W3039143487 creator A5087057933 @default.
- W3039143487 date "2020-07-04" @default.
- W3039143487 modified "2023-10-14" @default.
- W3039143487 title "Complement levels in patients with bloodstream infection due to Staphylococcus aureus or Gram-negative bacteria" @default.
- W3039143487 cites W1499722362 @default.
- W3039143487 cites W1513577262 @default.
- W3039143487 cites W1590582894 @default.
- W3039143487 cites W1592616574 @default.
- W3039143487 cites W1807843818 @default.
- W3039143487 cites W1904484517 @default.
- W3039143487 cites W1967005844 @default.
- W3039143487 cites W1984306568 @default.
- W3039143487 cites W1993578627 @default.
- W3039143487 cites W1997151890 @default.
- W3039143487 cites W2003500862 @default.
- W3039143487 cites W2016596675 @default.
- W3039143487 cites W2020936905 @default.
- W3039143487 cites W2022306256 @default.
- W3039143487 cites W2024242455 @default.
- W3039143487 cites W2033380685 @default.
- W3039143487 cites W2074514340 @default.
- W3039143487 cites W2078316771 @default.
- W3039143487 cites W2078484832 @default.
- W3039143487 cites W2080627037 @default.
- W3039143487 cites W2085277293 @default.
- W3039143487 cites W2102564040 @default.
- W3039143487 cites W2105751301 @default.
- W3039143487 cites W2109982451 @default.
- W3039143487 cites W2112663666 @default.
- W3039143487 cites W2122525035 @default.
- W3039143487 cites W2139717119 @default.
- W3039143487 cites W2142479896 @default.
- W3039143487 cites W2160675764 @default.
- W3039143487 cites W2161881689 @default.
- W3039143487 cites W2317184793 @default.
- W3039143487 cites W2331342695 @default.
- W3039143487 cites W2581605534 @default.
- W3039143487 cites W2599527603 @default.
- W3039143487 cites W2617620062 @default.
- W3039143487 cites W2744328790 @default.
- W3039143487 cites W2758042864 @default.
- W3039143487 cites W2807534664 @default.
- W3039143487 cites W2900612430 @default.
- W3039143487 cites W2941040405 @default.
- W3039143487 cites W2981172419 @default.
- W3039143487 cites W345004523 @default.
- W3039143487 cites W4256071109 @default.
- W3039143487 cites W4301177039 @default.
- W3039143487 doi "https://doi.org/10.1007/s10096-020-03955-z" @default.
- W3039143487 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7334117" @default.
- W3039143487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32621149" @default.
- W3039143487 hasPublicationYear "2020" @default.
- W3039143487 type Work @default.
- W3039143487 sameAs 3039143487 @default.
- W3039143487 citedByCount "7" @default.
- W3039143487 countsByYear W30391434872021 @default.
- W3039143487 countsByYear W30391434872022 @default.
- W3039143487 countsByYear W30391434872023 @default.
- W3039143487 crossrefType "journal-article" @default.
- W3039143487 hasAuthorship W3039143487A5011455639 @default.
- W3039143487 hasAuthorship W3039143487A5020327284 @default.
- W3039143487 hasAuthorship W3039143487A5036121557 @default.
- W3039143487 hasAuthorship W3039143487A5039854274 @default.
- W3039143487 hasAuthorship W3039143487A5045500368 @default.
- W3039143487 hasAuthorship W3039143487A5048740503 @default.
- W3039143487 hasAuthorship W3039143487A5079680275 @default.
- W3039143487 hasAuthorship W3039143487A5087057933 @default.
- W3039143487 hasBestOaLocation W30391434871 @default.
- W3039143487 hasConcept C111684460 @default.
- W3039143487 hasConcept C126322002 @default.
- W3039143487 hasConcept C190139176 @default.
- W3039143487 hasConcept C203014093 @default.
- W3039143487 hasConcept C2777628635 @default.
- W3039143487 hasConcept C2778384902 @default.
- W3039143487 hasConcept C2779443120 @default.
- W3039143487 hasConcept C2779489039 @default.
- W3039143487 hasConcept C2781300812 @default.
- W3039143487 hasConcept C501593827 @default.
- W3039143487 hasConcept C523546767 @default.
- W3039143487 hasConcept C54355233 @default.
- W3039143487 hasConcept C71924100 @default.
- W3039143487 hasConcept C86803240 @default.
- W3039143487 hasConcept C8891405 @default.
- W3039143487 hasConcept C89423630 @default.
- W3039143487 hasConceptScore W3039143487C111684460 @default.
- W3039143487 hasConceptScore W3039143487C126322002 @default.
- W3039143487 hasConceptScore W3039143487C190139176 @default.
- W3039143487 hasConceptScore W3039143487C203014093 @default.
- W3039143487 hasConceptScore W3039143487C2777628635 @default.