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- W3039195004 abstract "In this edition of Heart, Lung and Circulation, Holland et al. from a large Brisbane, Australia, hospital report their total experience of infective endocarditis (IE) over a 5-year period [ [1] Holland D.J. Simos P.A. Yoon J. Sivabalan P. Ramnarain J. Runnegar N.J. Infective endocarditis: a contemporary study of microbiology, echocardiography and associated clinical outcomes at a major tertiary referral centre. Heart Lung Circ. 2020; 29: 840-850 Abstract Full Text Full Text PDF PubMed Scopus (13) Google Scholar ]. They report on 204 consecutive cases, of which 70% were community-acquired and 30% were associated with health care, in particular with haemodialysis for renal failure. Out of all patients, 23% were in the context of intravenous drug use (IVDU). Staphylococcus aureus was the most commonly isolated organism in 45% of patients overall but was in 66% of the IVDU patients. The other important organisms were Streptococci, Enterococci and coagulase-negative Staphylococcus. As expected, left-sided vegetations were much more common in non-IVDU cases, while right-sided involvement was more common in IVDU cases. Almost 40% of patients underwent valve surgery, with valve replacement in about 70% of the operated cases. Most patients received a treatment course with a single antibiotic. The successful use of the outpatient parenteral antimicrobial therapy (OPAT) service was documented." @default.
- W3039195004 created "2020-07-10" @default.
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- W3039195004 date "2020-06-01" @default.
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- W3039195004 title "Managing Infective Endocarditis: What Lies Behind the High Mortality Rate and What Can We Do About it?" @default.
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- W3039195004 doi "https://doi.org/10.1016/j.hlc.2020.05.094" @default.
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