Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039356744> ?p ?o ?g. }
- W3039356744 abstract "Abstract Systems of amylose with nimesulide or tretinoin are prepared and characterized in order to evaluate their in vitro release behavior. X‐ray diffraction (XRD) data of the amylose systems containing drug molecules reveal patterns characteristic of the V‐type of complexed amylose. Nevertheless, they cannot be unequivocally assigned to complexed amylose since both drugs exhibit XRD reflections at similar 2‐theta angles. Raman scattering and differential scanning calorimetry thermal analysis provide evidence suggesting that tretinoin is more likely to form molecular inclusion complexes than nimesulide. The drug–amylose interaction is also assessed by means of optical microscopy, confocal laser scanning microscopy, and scanning electron microscopy. The results reveal that the drug molecules are effectively entrapped in the amylose matrix, probably inside or between the amylose helices. Acidic and enzymatic tests allow the quantification of the drug molecules released from the matrix of the amylose systems with tretinoin or nimesulide. In the simulated intestinal fluid, the drug release of the samples reached up to ≈52% for tretinoin and ≈39% for nimesulide systems. Overall, the results show that the molecular interaction of amylose, with tretinoin appears to be more promising for efficient complexation than with nimesulide." @default.
- W3039356744 created "2020-07-10" @default.
- W3039356744 creator A5035767004 @default.
- W3039356744 creator A5043442712 @default.
- W3039356744 creator A5048146412 @default.
- W3039356744 creator A5085353356 @default.
- W3039356744 date "2020-07-10" @default.
- W3039356744 modified "2023-10-18" @default.
- W3039356744 title "Interaction of Tretinoin and Nimesulide with Amylose Matrices" @default.
- W3039356744 cites W1522767714 @default.
- W3039356744 cites W1554600230 @default.
- W3039356744 cites W1973445650 @default.
- W3039356744 cites W1980033294 @default.
- W3039356744 cites W1985304698 @default.
- W3039356744 cites W1986239626 @default.
- W3039356744 cites W1986654230 @default.
- W3039356744 cites W1987642509 @default.
- W3039356744 cites W1994591998 @default.
- W3039356744 cites W1995887171 @default.
- W3039356744 cites W1999028339 @default.
- W3039356744 cites W2006408824 @default.
- W3039356744 cites W2010223637 @default.
- W3039356744 cites W2018081140 @default.
- W3039356744 cites W2020472200 @default.
- W3039356744 cites W2021342943 @default.
- W3039356744 cites W2025542433 @default.
- W3039356744 cites W2028407217 @default.
- W3039356744 cites W2030431187 @default.
- W3039356744 cites W2033683526 @default.
- W3039356744 cites W2036495529 @default.
- W3039356744 cites W2037482405 @default.
- W3039356744 cites W2045494738 @default.
- W3039356744 cites W2052435800 @default.
- W3039356744 cites W2052577718 @default.
- W3039356744 cites W2053152610 @default.
- W3039356744 cites W2061955697 @default.
- W3039356744 cites W2063250875 @default.
- W3039356744 cites W2065699106 @default.
- W3039356744 cites W2067842386 @default.
- W3039356744 cites W2079713654 @default.
- W3039356744 cites W2082732127 @default.
- W3039356744 cites W2089252851 @default.
- W3039356744 cites W2089288298 @default.
- W3039356744 cites W2103846305 @default.
- W3039356744 cites W2109448576 @default.
- W3039356744 cites W2116408811 @default.
- W3039356744 cites W2118660038 @default.
- W3039356744 cites W2126079216 @default.
- W3039356744 cites W2144374279 @default.
- W3039356744 cites W2151418987 @default.
- W3039356744 cites W2154703584 @default.
- W3039356744 cites W2157528739 @default.
- W3039356744 cites W2211723313 @default.
- W3039356744 cites W2216980933 @default.
- W3039356744 cites W2238595803 @default.
- W3039356744 cites W2282658219 @default.
- W3039356744 cites W2290121688 @default.
- W3039356744 cites W2407345634 @default.
- W3039356744 cites W2535614730 @default.
- W3039356744 cites W2557990427 @default.
- W3039356744 cites W2588888588 @default.
- W3039356744 cites W2734754609 @default.
- W3039356744 cites W2767194831 @default.
- W3039356744 cites W2810772648 @default.
- W3039356744 cites W2884835431 @default.
- W3039356744 cites W2889638176 @default.
- W3039356744 cites W2913908098 @default.
- W3039356744 cites W2919004567 @default.
- W3039356744 cites W4205845602 @default.
- W3039356744 cites W4236726013 @default.
- W3039356744 cites W4242808567 @default.
- W3039356744 cites W4245316645 @default.
- W3039356744 cites W4375905889 @default.
- W3039356744 cites W767325190 @default.
- W3039356744 cites W2061451027 @default.
- W3039356744 doi "https://doi.org/10.1002/star.202000054" @default.
- W3039356744 hasPublicationYear "2020" @default.
- W3039356744 type Work @default.
- W3039356744 sameAs 3039356744 @default.
- W3039356744 citedByCount "6" @default.
- W3039356744 countsByYear W30393567442021 @default.
- W3039356744 countsByYear W30393567442022 @default.
- W3039356744 countsByYear W30393567442023 @default.
- W3039356744 crossrefType "journal-article" @default.
- W3039356744 hasAuthorship W3039356744A5035767004 @default.
- W3039356744 hasAuthorship W3039356744A5043442712 @default.
- W3039356744 hasAuthorship W3039356744A5048146412 @default.
- W3039356744 hasAuthorship W3039356744A5085353356 @default.
- W3039356744 hasConcept C121332964 @default.
- W3039356744 hasConcept C178790620 @default.
- W3039356744 hasConcept C185592680 @default.
- W3039356744 hasConcept C2776804113 @default.
- W3039356744 hasConcept C2777570176 @default.
- W3039356744 hasConcept C32909587 @default.
- W3039356744 hasConcept C39519442 @default.
- W3039356744 hasConcept C529335014 @default.
- W3039356744 hasConcept C55493867 @default.
- W3039356744 hasConcept C97355855 @default.
- W3039356744 hasConceptScore W3039356744C121332964 @default.
- W3039356744 hasConceptScore W3039356744C178790620 @default.