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- W3039370596 endingPage "4760" @default.
- W3039370596 startingPage "4760" @default.
- W3039370596 abstract "Cerebrospinal fluid (CSF) is the liquid that fills the brain ventricles. CSF represents not only a mechanical brain protection but also a rich source of signalling factors modulating diverse processes during brain development and adulthood. The choroid plexus (CP) is a major source of CSF and as such it has recently emerged as an important mediator of extracellular signalling within the brain. Growing interest in the CP revealed its capacity to release a broad variety of bioactive molecules that, via CSF, regulate processes across the whole central nervous system (CNS). Moreover, CP has been also recognized as a sensor, responding to altered composition of CSF associated with changes in the patterns of CNS activity. In this review, we summarize the recent advances in our understanding of the CP as a signalling centre that mediates long-range communication in the CNS. By providing a detailed account of the CP secretory repertoire, we describe how the CP contributes to the regulation of the extracellular environment—in the context of both the embryonal as well as the adult CNS. We highlight the role of the CP as an important regulator of CNS function that acts via CSF-mediated signalling. Further studies of CP–CSF signalling hold the potential to provide key insights into the biology of the CNS, with implications for better understanding and treatment of neuropathological conditions." @default.
- W3039370596 created "2020-07-10" @default.
- W3039370596 creator A5055528010 @default.
- W3039370596 creator A5059929737 @default.
- W3039370596 date "2020-07-04" @default.
- W3039370596 modified "2023-10-18" @default.
- W3039370596 title "Choroid Plexus: The Orchestrator of Long-Range Signalling Within the CNS" @default.
- W3039370596 cites W1495762998 @default.
- W3039370596 cites W1555875393 @default.
- W3039370596 cites W1597383969 @default.
- W3039370596 cites W1897721574 @default.
- W3039370596 cites W1903015803 @default.
- W3039370596 cites W1952209856 @default.
- W3039370596 cites W1964764355 @default.
- W3039370596 cites W1964938632 @default.
- W3039370596 cites W1967277092 @default.
- W3039370596 cites W1967611229 @default.
- W3039370596 cites W1969040921 @default.
- W3039370596 cites W1972534926 @default.
- W3039370596 cites W1972912923 @default.
- W3039370596 cites W1973125013 @default.
- W3039370596 cites W1974392986 @default.
- W3039370596 cites W1974878596 @default.
- W3039370596 cites W1980632075 @default.
- W3039370596 cites W1981885339 @default.
- W3039370596 cites W1983050931 @default.
- W3039370596 cites W1984112963 @default.
- W3039370596 cites W1986833872 @default.
- W3039370596 cites W1989434690 @default.
- W3039370596 cites W1990630439 @default.
- W3039370596 cites W1994756206 @default.
- W3039370596 cites W1994814634 @default.
- W3039370596 cites W1996090995 @default.
- W3039370596 cites W2000845808 @default.
- W3039370596 cites W2001065761 @default.
- W3039370596 cites W2003555906 @default.
- W3039370596 cites W2004134964 @default.
- W3039370596 cites W2004207259 @default.
- W3039370596 cites W2009511207 @default.
- W3039370596 cites W2010704206 @default.
- W3039370596 cites W2017978637 @default.
- W3039370596 cites W2018504812 @default.
- W3039370596 cites W2023512658 @default.
- W3039370596 cites W2024357833 @default.
- W3039370596 cites W2026598324 @default.
- W3039370596 cites W2028369178 @default.
- W3039370596 cites W2028776222 @default.
- W3039370596 cites W2029987970 @default.
- W3039370596 cites W2032696674 @default.
- W3039370596 cites W2035006113 @default.
- W3039370596 cites W2035731516 @default.
- W3039370596 cites W2036036394 @default.
- W3039370596 cites W2037116976 @default.
- W3039370596 cites W2037788197 @default.
- W3039370596 cites W2038078051 @default.
- W3039370596 cites W2039905092 @default.
- W3039370596 cites W2044723966 @default.
- W3039370596 cites W2047181007 @default.
- W3039370596 cites W2049147669 @default.
- W3039370596 cites W2050025596 @default.
- W3039370596 cites W2052621721 @default.
- W3039370596 cites W2052679565 @default.
- W3039370596 cites W2055149141 @default.
- W3039370596 cites W2061769617 @default.
- W3039370596 cites W2064669449 @default.
- W3039370596 cites W2069207545 @default.
- W3039370596 cites W2070359873 @default.
- W3039370596 cites W2079330864 @default.
- W3039370596 cites W2081902249 @default.
- W3039370596 cites W2082105302 @default.
- W3039370596 cites W2082372465 @default.
- W3039370596 cites W2082910363 @default.
- W3039370596 cites W2085636386 @default.
- W3039370596 cites W2088135594 @default.
- W3039370596 cites W2089464935 @default.
- W3039370596 cites W2095851810 @default.
- W3039370596 cites W2096964291 @default.
- W3039370596 cites W2097469682 @default.
- W3039370596 cites W2104520647 @default.
- W3039370596 cites W2111800376 @default.
- W3039370596 cites W2113435863 @default.
- W3039370596 cites W2115599658 @default.
- W3039370596 cites W2115879423 @default.
- W3039370596 cites W2132998420 @default.
- W3039370596 cites W2133638057 @default.
- W3039370596 cites W2133670747 @default.
- W3039370596 cites W2138765408 @default.
- W3039370596 cites W2140420135 @default.
- W3039370596 cites W2141623310 @default.
- W3039370596 cites W2144102348 @default.
- W3039370596 cites W2146427652 @default.
- W3039370596 cites W2147063219 @default.
- W3039370596 cites W2149754187 @default.
- W3039370596 cites W2159252214 @default.
- W3039370596 cites W2161009818 @default.
- W3039370596 cites W2167183660 @default.
- W3039370596 cites W2168806799 @default.
- W3039370596 cites W2172166196 @default.