FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039394493> ?p ?o ?g. }

• W3039394493 endingPage "101480" @default.
• W3039394493 startingPage "101480" @default.
• W3039394493 abstract "An advanced liver fibrosis did not abolish an Egyptian ethnicity as a favourable predictor for hepatitis C genotype 4 (HCV-GT4) outcome, that raises genetic issues.Multiple databases were searched from inception up to 1 April, 2020 for all studies included Egyptians, whose were genotyped for Interleukin-28B (IL-B28) in the setting of HCV. The pooled odds ratios (ORs) were based on a fixed or random effect model as appropriate.In total, 33 studies included 5,538 Egyptians from 9 governorates. Of these, 4088 patients had chronic HCV-GT4, 373 resolvers (spontaneously cleared the virus), and 1077 non-infected subjects. The pooled prevalence of CC and CT/TT rs12979860 genotypes among chronic HCV-GT4 were 32%, and 68%, respectively. The pooled sustained virologic response (SVR) was achieved in 54% of 2,622 patients received Pegylated-interferon and Ribavirin. Compared with chronic HCV-infected patients, the favorable CC genotype was over-represented in the healthy subjects (30% vs. 45%), and HCV resolvers (28% vs. 59%). The CC genotype carriers were two-times more likely to resist HCV infection (vs.OR=1.93, P<0.001), three-times (OR=3.31, P<0.001) to clear the virus spontaneously, and six-times to achieve interferon-induced SVR (ORcorrected=6.03; P<0.001). The rs8099917 TT carriers were associated with a higher rate of SVR (vs. wild GT/GG, 74% vs. 38%), with 3-fold probability achieving SVR (ORcorrected=3.42, P<0.001).Polymorphisms near the IL-28B gene protect against infection and persistence of HCV, and predict SVR." @default.
• W3039394493 created "2020-07-10" @default.
• W3039394493 creator A5012573402 @default.
• W3039394493 date "2021-03-01" @default.
• W3039394493 modified "2023-10-16" @default.
• W3039394493 title "Predictive power of Interleukin–28B gene variants for outcome of Hepatitis C Virus genotype 4 in Egyptians: A systematic review and meta-analysis" @default.
• W3039394493 cites W1144419101 @default.
• W3039394493 cites W1240849929 @default.
• W3039394493 cites W1480336461 @default.
• W3039394493 cites W1634126738 @default.
• W3039394493 cites W1903130565 @default.
• W3039394493 cites W1950173781 @default.
• W3039394493 cites W1977662353 @default.
• W3039394493 cites W1981036435 @default.
• W3039394493 cites W1982171695 @default.
• W3039394493 cites W1985473671 @default.
• W3039394493 cites W1988507131 @default.
• W3039394493 cites W2001183236 @default.
• W3039394493 cites W2009064936 @default.
• W3039394493 cites W2011124302 @default.
• W3039394493 cites W2023481708 @default.
• W3039394493 cites W2024493120 @default.
• W3039394493 cites W2028990156 @default.
• W3039394493 cites W2029049099 @default.
• W3039394493 cites W2029518991 @default.
• W3039394493 cites W2058538904 @default.
• W3039394493 cites W2063285149 @default.
• W3039394493 cites W2070755355 @default.
• W3039394493 cites W2072453168 @default.
• W3039394493 cites W2072731749 @default.
• W3039394493 cites W2073113951 @default.
• W3039394493 cites W2075550072 @default.
• W3039394493 cites W2077960757 @default.
• W3039394493 cites W2084364820 @default.
• W3039394493 cites W2086414517 @default.
• W3039394493 cites W2093977114 @default.
• W3039394493 cites W2100795544 @default.
• W3039394493 cites W2106110144 @default.
• W3039394493 cites W2107823673 @default.
• W3039394493 cites W2116319809 @default.
• W3039394493 cites W2120904390 @default.
• W3039394493 cites W2126930838 @default.
• W3039394493 cites W2156903246 @default.
• W3039394493 cites W2157823046 @default.
• W3039394493 cites W2160489010 @default.
• W3039394493 cites W2168229737 @default.
• W3039394493 cites W2241375141 @default.
• W3039394493 cites W2280057995 @default.
• W3039394493 cites W2332785053 @default.
• W3039394493 cites W2513979889 @default.
• W3039394493 cites W2530530969 @default.
• W3039394493 cites W2611989377 @default.
• W3039394493 cites W2772996414 @default.
• W3039394493 cites W2884584310 @default.
• W3039394493 cites W2900414083 @default.
• W3039394493 cites W3021357922 @default.
• W3039394493 cites W330756305 @default.
• W3039394493 cites W4245216028 @default.
• W3039394493 cites W577173713 @default.
• W3039394493 cites W871291096 @default.
• W3039394493 doi "https://doi.org/10.1016/j.clinre.2020.06.006" @default.
• W3039394493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32622719" @default.
• W3039394493 hasPublicationYear "2021" @default.
• W3039394493 type Work @default.
• W3039394493 sameAs 3039394493 @default.
• W3039394493 citedByCount "0" @default.
• W3039394493 crossrefType "journal-article" @default.
• W3039394493 hasAuthorship W3039394493A5012573402 @default.
• W3039394493 hasBestOaLocation W30393944931 @default.
• W3039394493 hasConcept C104317684 @default.
• W3039394493 hasConcept C126322002 @default.
• W3039394493 hasConcept C135763542 @default.
• W3039394493 hasConcept C156957248 @default.
• W3039394493 hasConcept C159047783 @default.
• W3039394493 hasConcept C203014093 @default.
• W3039394493 hasConcept C2522874641 @default.
• W3039394493 hasConcept C2776178377 @default.
• W3039394493 hasConcept C2776408679 @default.
• W3039394493 hasConcept C2776455275 @default.
• W3039394493 hasConcept C2776461080 @default.
• W3039394493 hasConcept C2780040827 @default.
• W3039394493 hasConcept C2781399841 @default.
• W3039394493 hasConcept C54355233 @default.
• W3039394493 hasConcept C71924100 @default.
• W3039394493 hasConcept C86803240 @default.
• W3039394493 hasConcept C90924648 @default.
• W3039394493 hasConceptScore W3039394493C104317684 @default.
• W3039394493 hasConceptScore W3039394493C126322002 @default.
• W3039394493 hasConceptScore W3039394493C135763542 @default.
• W3039394493 hasConceptScore W3039394493C156957248 @default.
• W3039394493 hasConceptScore W3039394493C159047783 @default.
• W3039394493 hasConceptScore W3039394493C203014093 @default.
• W3039394493 hasConceptScore W3039394493C2522874641 @default.
• W3039394493 hasConceptScore W3039394493C2776178377 @default.
• W3039394493 hasConceptScore W3039394493C2776408679 @default.
• W3039394493 hasConceptScore W3039394493C2776455275 @default.
• W3039394493 hasConceptScore W3039394493C2776461080 @default.
• W3039394493 hasConceptScore W3039394493C2780040827 @default.

• next