FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039406103> ?p ?o ?g. }

• W3039406103 abstract "Parvalbumin-expressing interneurons (PVs) in the dentate gyrus provide activity-dependent regulation of adult neurogenesis as well as maintain inhibitory control of mature neurons. In mature neurons, PVs evoke GABAA postsynaptic currents (GPSCs) with fast rise and decay phases that allow precise control of spike timing, yet synaptic currents with fast kinetics do not appear in adult-born neurons until several weeks after cell birth. Here we used mouse hippocampal slices to address how PVs signal to newborn neurons prior to the appearance of fast GPSCs. Whereas PV-evoked currents in mature neurons exhibit hallmark fast rise and decay phases, newborn neurons display slow GPSCs with characteristics of spillover signaling. We also unmasked slow spillover currents in mature neurons in the absence of fast GPSCs. Our results suggest that PVs mediate slow spillover signaling in addition to conventional fast synaptic signaling, and that spillover transmission mediates activity-dependent regulation of early events in adult neurogenesis." @default.
• W3039406103 created "2020-07-10" @default.
• W3039406103 creator A5010981709 @default.
• W3039406103 creator A5028420051 @default.
• W3039406103 creator A5040077367 @default.
• W3039406103 creator A5045519629 @default.
• W3039406103 creator A5052488034 @default.
• W3039406103 creator A5055259148 @default.
• W3039406103 creator A5063624982 @default.
• W3039406103 creator A5064198022 @default.
• W3039406103 creator A5089456286 @default.
• W3039406103 date "2020-06-30" @default.
• W3039406103 modified "2023-09-27" @default.
• W3039406103 title "Parvalbumin interneurons provide spillover to newborn and mature dentate granule cells" @default.
• W3039406103 cites W1492566897 @default.
• W3039406103 cites W1492710069 @default.
• W3039406103 cites W1516995431 @default.
• W3039406103 cites W1566057978 @default.
• W3039406103 cites W1569243743 @default.
• W3039406103 cites W1861463350 @default.
• W3039406103 cites W1963648748 @default.
• W3039406103 cites W1963900457 @default.
• W3039406103 cites W1977516874 @default.
• W3039406103 cites W1993861337 @default.
• W3039406103 cites W1997285021 @default.
• W3039406103 cites W1999785181 @default.
• W3039406103 cites W2000520243 @default.
• W3039406103 cites W2002426597 @default.
• W3039406103 cites W2003059369 @default.
• W3039406103 cites W2004000308 @default.
• W3039406103 cites W2004937932 @default.
• W3039406103 cites W2005626767 @default.
• W3039406103 cites W2010575361 @default.
• W3039406103 cites W2014460069 @default.
• W3039406103 cites W2016662169 @default.
• W3039406103 cites W2016676279 @default.
• W3039406103 cites W2017884282 @default.
• W3039406103 cites W2024571276 @default.
• W3039406103 cites W2030028265 @default.
• W3039406103 cites W2030119843 @default.
• W3039406103 cites W2033349636 @default.
• W3039406103 cites W2036270719 @default.
• W3039406103 cites W2040574649 @default.
• W3039406103 cites W2042027195 @default.
• W3039406103 cites W2044965161 @default.
• W3039406103 cites W2049132832 @default.
• W3039406103 cites W2049220190 @default.
• W3039406103 cites W2057386575 @default.
• W3039406103 cites W2058022492 @default.
• W3039406103 cites W2061619540 @default.
• W3039406103 cites W2064547319 @default.
• W3039406103 cites W2066902435 @default.
• W3039406103 cites W2067501282 @default.
• W3039406103 cites W2069374541 @default.
• W3039406103 cites W2069860218 @default.
• W3039406103 cites W2073536847 @default.
• W3039406103 cites W2077716014 @default.
• W3039406103 cites W2081026643 @default.
• W3039406103 cites W2084072056 @default.
• W3039406103 cites W2085107866 @default.
• W3039406103 cites W2090137827 @default.
• W3039406103 cites W2094183469 @default.
• W3039406103 cites W2105722729 @default.
• W3039406103 cites W2111004700 @default.
• W3039406103 cites W2117551534 @default.
• W3039406103 cites W2117918613 @default.
• W3039406103 cites W2121009504 @default.
• W3039406103 cites W2124237348 @default.
• W3039406103 cites W2127732414 @default.
• W3039406103 cites W2128725941 @default.
• W3039406103 cites W2138412572 @default.
• W3039406103 cites W2142010321 @default.
• W3039406103 cites W2142604892 @default.
• W3039406103 cites W2151189924 @default.
• W3039406103 cites W2157485658 @default.
• W3039406103 cites W2178407419 @default.
• W3039406103 cites W2192476518 @default.
• W3039406103 cites W2408615049 @default.
• W3039406103 cites W2470980998 @default.
• W3039406103 cites W2529699144 @default.
• W3039406103 cites W2543294033 @default.
• W3039406103 cites W2759536331 @default.
• W3039406103 cites W2760548460 @default.
• W3039406103 cites W2762878098 @default.
• W3039406103 cites W2805486048 @default.
• W3039406103 cites W2808698240 @default.
• W3039406103 cites W2899494972 @default.
• W3039406103 cites W2953674280 @default.
• W3039406103 cites W2965372978 @default.
• W3039406103 cites W2979742203 @default.
• W3039406103 cites W3000406072 @default.
• W3039406103 cites W4313635088 @default.
• W3039406103 doi "https://doi.org/10.7554/elife.54125" @default.
• W3039406103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7326496" @default.
• W3039406103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32602839" @default.
• W3039406103 hasPublicationYear "2020" @default.
• W3039406103 type Work @default.
• W3039406103 sameAs 3039406103 @default.
• W3039406103 citedByCount "15" @default.
• W3039406103 countsByYear W30394061032020 @default.

• next