Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039536666> ?p ?o ?g. }
- W3039536666 abstract "Abstract In naturally occurring microbial systems, species rarely exist in isolation. There is strong ecological evidence for a positive relationship between species diversity and the functional output of communities. The pervasiveness of these communities in nature highlights that there may be advantages for engineered strains to exist in cocultures as well. Building synthetic microbial communities allows us to create distributed systems that mitigates issues often found in engineering a monoculture, especially when functional complexity is increasing. Here, we demonstrate a methodology for designing robust synthetic communities that use quorum sensing to control amensal bacteriocin interactions in a chemostat environment. We explore model spaces for two and three strain systems, using Bayesian methods to perform model selection, and identify the most robust candidates for producing stable steady state communities. Our findings highlight important interaction motifs that provide stability, and identify requirements for selecting genetic parts and tuning the community composition." @default.
- W3039536666 created "2020-07-10" @default.
- W3039536666 creator A5031424617 @default.
- W3039536666 creator A5032623412 @default.
- W3039536666 creator A5051465177 @default.
- W3039536666 date "2020-07-01" @default.
- W3039536666 modified "2023-09-25" @default.
- W3039536666 title "Automated design of synthetic microbial communities" @default.
- W3039536666 cites W1535101580 @default.
- W3039536666 cites W1570124823 @default.
- W3039536666 cites W1902027874 @default.
- W3039536666 cites W1963204303 @default.
- W3039536666 cites W1968033606 @default.
- W3039536666 cites W1970559599 @default.
- W3039536666 cites W1998240064 @default.
- W3039536666 cites W2007105977 @default.
- W3039536666 cites W2023893235 @default.
- W3039536666 cites W2037857799 @default.
- W3039536666 cites W2039940889 @default.
- W3039536666 cites W2040539560 @default.
- W3039536666 cites W2043659101 @default.
- W3039536666 cites W2047360542 @default.
- W3039536666 cites W2062188770 @default.
- W3039536666 cites W2067303073 @default.
- W3039536666 cites W2076393137 @default.
- W3039536666 cites W2076477598 @default.
- W3039536666 cites W2078779451 @default.
- W3039536666 cites W2079536459 @default.
- W3039536666 cites W2079593650 @default.
- W3039536666 cites W2079828141 @default.
- W3039536666 cites W2089474999 @default.
- W3039536666 cites W2090516577 @default.
- W3039536666 cites W2095355446 @default.
- W3039536666 cites W2102681753 @default.
- W3039536666 cites W2103138883 @default.
- W3039536666 cites W2105662588 @default.
- W3039536666 cites W2110232499 @default.
- W3039536666 cites W2116686857 @default.
- W3039536666 cites W2119438916 @default.
- W3039536666 cites W2126922170 @default.
- W3039536666 cites W2132215950 @default.
- W3039536666 cites W2135141237 @default.
- W3039536666 cites W2138358136 @default.
- W3039536666 cites W2138835511 @default.
- W3039536666 cites W2145352273 @default.
- W3039536666 cites W2152246075 @default.
- W3039536666 cites W2157967771 @default.
- W3039536666 cites W2161466984 @default.
- W3039536666 cites W2165608379 @default.
- W3039536666 cites W2169010693 @default.
- W3039536666 cites W2285600743 @default.
- W3039536666 cites W2337055076 @default.
- W3039536666 cites W2382100040 @default.
- W3039536666 cites W2397945787 @default.
- W3039536666 cites W2529784919 @default.
- W3039536666 cites W2560296415 @default.
- W3039536666 cites W2561541979 @default.
- W3039536666 cites W2564588533 @default.
- W3039536666 cites W2588456700 @default.
- W3039536666 cites W2625497715 @default.
- W3039536666 cites W2809425738 @default.
- W3039536666 cites W2943787518 @default.
- W3039536666 cites W2949808248 @default.
- W3039536666 cites W2950452652 @default.
- W3039536666 cites W2951096514 @default.
- W3039536666 cites W2953098897 @default.
- W3039536666 cites W2966237986 @default.
- W3039536666 cites W2971306961 @default.
- W3039536666 cites W2971439707 @default.
- W3039536666 cites W2971658418 @default.
- W3039536666 cites W2972369164 @default.
- W3039536666 cites W3006347143 @default.
- W3039536666 cites W3015713838 @default.
- W3039536666 cites W3105621610 @default.
- W3039536666 cites W4255582690 @default.
- W3039536666 cites W3021188621 @default.
- W3039536666 doi "https://doi.org/10.1101/2020.06.30.180281" @default.
- W3039536666 hasPublicationYear "2020" @default.
- W3039536666 type Work @default.
- W3039536666 sameAs 3039536666 @default.
- W3039536666 citedByCount "1" @default.
- W3039536666 countsByYear W30395366662022 @default.
- W3039536666 crossrefType "posted-content" @default.
- W3039536666 hasAuthorship W3039536666A5031424617 @default.
- W3039536666 hasAuthorship W3039536666A5032623412 @default.
- W3039536666 hasAuthorship W3039536666A5051465177 @default.
- W3039536666 hasBestOaLocation W30395366661 @default.
- W3039536666 hasConcept C112972136 @default.
- W3039536666 hasConcept C118687296 @default.
- W3039536666 hasConcept C119857082 @default.
- W3039536666 hasConcept C125111812 @default.
- W3039536666 hasConcept C127413603 @default.
- W3039536666 hasConcept C154945302 @default.
- W3039536666 hasConcept C183696295 @default.
- W3039536666 hasConcept C18903297 @default.
- W3039536666 hasConcept C191908910 @default.
- W3039536666 hasConcept C2775941552 @default.
- W3039536666 hasConcept C2988890453 @default.
- W3039536666 hasConcept C41008148 @default.
- W3039536666 hasConcept C47318914 @default.