Matches in SemOpenAlex for { <https://semopenalex.org/work/W3039580642> ?p ?o ?g. }
- W3039580642 endingPage "374" @default.
- W3039580642 startingPage "366" @default.
- W3039580642 abstract "With the rapid development of biomedicine applications, more flexible and efficient fabrication strategies are required for drug delivery vehicles. Naturally resourced polymers have gained considerable attention for construction of drug carriers. Here, biocompatible hydrogel reservoir system (named PHG-PDA) based on pullulan and polydopamine (PDA) are designed and fabricated by one-pot incorporation of PDA fibers into pullulan hydrogel (PHG). The structure and performance of the PHG-PDAs can be nicely adjusted by regulating the content of PDA fibers in precursor hydrogel solutions. Crystal violet is used as a drug prototype and introduced into hydrogels via swelling-diffusion approach. We found that the drug loading process followed the pseudo-second-order model and Langmuir isotherm model, while the drug releasing process was pH-responsive, and the cumulative release reached 60.3% and 87% at pH 7.4 and 5.0, respectively. In vitro cytotoxicity studies on L929 cells demonstrated that our hydrogels were nontoxic even in a high concentration (3.4 mg/mL). In sum, these biocompatible PHG-PDAs with tunable physicochemical properties are promising systems for drug delivery." @default.
- W3039580642 created "2020-07-10" @default.
- W3039580642 creator A5001887101 @default.
- W3039580642 creator A5012556817 @default.
- W3039580642 creator A5025143275 @default.
- W3039580642 creator A5059686406 @default.
- W3039580642 creator A5088558075 @default.
- W3039580642 date "2020-11-01" @default.
- W3039580642 modified "2023-10-17" @default.
- W3039580642 title "Facile fabrication of functional hydrogels consisting of pullulan and polydopamine fibers for drug delivery" @default.
- W3039580642 cites W1798455107 @default.
- W3039580642 cites W2010750052 @default.
- W3039580642 cites W2463817783 @default.
- W3039580642 cites W2600606217 @default.
- W3039580642 cites W2751591735 @default.
- W3039580642 cites W2780262188 @default.
- W3039580642 cites W2789973015 @default.
- W3039580642 cites W2792635487 @default.
- W3039580642 cites W2795945130 @default.
- W3039580642 cites W2796705756 @default.
- W3039580642 cites W2797630566 @default.
- W3039580642 cites W2798187196 @default.
- W3039580642 cites W2803524584 @default.
- W3039580642 cites W2805345717 @default.
- W3039580642 cites W2818235490 @default.
- W3039580642 cites W2888245185 @default.
- W3039580642 cites W2888839768 @default.
- W3039580642 cites W2889289556 @default.
- W3039580642 cites W2889472525 @default.
- W3039580642 cites W2890476384 @default.
- W3039580642 cites W2894945386 @default.
- W3039580642 cites W2904387388 @default.
- W3039580642 cites W2908678585 @default.
- W3039580642 cites W2911657477 @default.
- W3039580642 cites W2916258664 @default.
- W3039580642 cites W2926385830 @default.
- W3039580642 cites W2951535199 @default.
- W3039580642 cites W2956094389 @default.
- W3039580642 cites W2963718541 @default.
- W3039580642 cites W2964031811 @default.
- W3039580642 cites W2966638784 @default.
- W3039580642 cites W2968532801 @default.
- W3039580642 cites W2968799065 @default.
- W3039580642 cites W2976740715 @default.
- W3039580642 cites W2980382297 @default.
- W3039580642 cites W2981329874 @default.
- W3039580642 cites W2981719270 @default.
- W3039580642 cites W2982350614 @default.
- W3039580642 cites W2982559076 @default.
- W3039580642 cites W2989876152 @default.
- W3039580642 cites W2990147055 @default.
- W3039580642 cites W2995691265 @default.
- W3039580642 cites W2999477244 @default.
- W3039580642 cites W2999834265 @default.
- W3039580642 cites W3002523290 @default.
- W3039580642 cites W3003689550 @default.
- W3039580642 cites W3005381464 @default.
- W3039580642 cites W3006957718 @default.
- W3039580642 cites W3008694134 @default.
- W3039580642 cites W3009030020 @default.
- W3039580642 cites W3012165486 @default.
- W3039580642 cites W3016690131 @default.
- W3039580642 doi "https://doi.org/10.1016/j.ijbiomac.2020.06.283" @default.
- W3039580642 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32629062" @default.
- W3039580642 hasPublicationYear "2020" @default.
- W3039580642 type Work @default.
- W3039580642 sameAs 3039580642 @default.
- W3039580642 citedByCount "71" @default.
- W3039580642 countsByYear W30395806422020 @default.
- W3039580642 countsByYear W30395806422021 @default.
- W3039580642 countsByYear W30395806422022 @default.
- W3039580642 countsByYear W30395806422023 @default.
- W3039580642 crossrefType "journal-article" @default.
- W3039580642 hasAuthorship W3039580642A5001887101 @default.
- W3039580642 hasAuthorship W3039580642A5012556817 @default.
- W3039580642 hasAuthorship W3039580642A5025143275 @default.
- W3039580642 hasAuthorship W3039580642A5059686406 @default.
- W3039580642 hasAuthorship W3039580642A5088558075 @default.
- W3039580642 hasConcept C100817775 @default.
- W3039580642 hasConcept C108586683 @default.
- W3039580642 hasConcept C127413603 @default.
- W3039580642 hasConcept C1318750 @default.
- W3039580642 hasConcept C136229726 @default.
- W3039580642 hasConcept C136525101 @default.
- W3039580642 hasConcept C142724271 @default.
- W3039580642 hasConcept C159985019 @default.
- W3039580642 hasConcept C171250308 @default.
- W3039580642 hasConcept C178790620 @default.
- W3039580642 hasConcept C185592680 @default.
- W3039580642 hasConcept C188027245 @default.
- W3039580642 hasConcept C192562407 @default.
- W3039580642 hasConcept C204787440 @default.
- W3039580642 hasConcept C2778540859 @default.
- W3039580642 hasConcept C2779257994 @default.
- W3039580642 hasConcept C2779820397 @default.
- W3039580642 hasConcept C2780035454 @default.
- W3039580642 hasConcept C42360764 @default.
- W3039580642 hasConcept C71924100 @default.