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• W3039686052 abstract "In a biological membrane, proteins require specific lipids of distinctive length and chain saturation surrounding them. The active tuning of the membrane thickness therefore opens new possibilities in the study and manipulation of membrane proteins. Here, we introduce the concept of stapling phospholipids to different degrees of interdigitation depth by mixing 1,3-diamidophospholipids with single-chain bolalipids. The mixed membranes were studied by calorimetric assays, electron microscopy, X-ray, and infrared measurements to provide a complete biophysical characterization of membrane stapling. The matching between the diamidophospholipids and the bolalipids can be so strong as to completely induce a new phase that is more stable than the gel phase of the individual components." @default.
• W3039686052 created "2020-07-10" @default.
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• W3039686052 date "2020-07-01" @default.
• W3039686052 modified "2023-09-24" @default.
• W3039686052 title "Tuning the Thickness of a Biomembrane by Stapling Diamidophospholipids with Bolalipids" @default.
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• W3039686052 doi "https://doi.org/10.1021/acs.langmuir.0c01522" @default.
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