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- W3039777621 abstract "Zinc crosslinked supramolecular hydrogels from O-carboxymethyl chitosan biguanidine were successfully prepared. The structures of the prepared hydrogels were verified by 1H NMR, FTIR and XRD. FE-SEM verified the porous structure of hydrogels especially at high contents of Zn2+ ions. The integral procedure decomposition temperatures calculated from TGA curves showed that the thermal stability was increased upon increasing the content of Zn2+ ions. Cytotoxicity assays confirmed that the amounts of Zn2+ ions released from hydrogels were below the toxic level towards a breast cancer cell line (MCF-7). The prepared hydrogels exhibited a significant microbial inhibition towards different species of bacteria and fungi, particularly at high Zn contents. Based on the obtained interesting data, the prepared zinc/O-carboxymethyl chitosan biguanidine could be used in drug delivery and biomedical applications." @default.
- W3039777621 created "2020-07-10" @default.
- W3039777621 creator A5046629410 @default.
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- W3039777621 date "2020-11-01" @default.
- W3039777621 modified "2023-10-03" @default.
- W3039777621 title "Novel biocompatible and antimicrobial supramolecular O-carboxymethyl chitosan biguanidine/zinc physical hydrogels" @default.
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- W3039777621 doi "https://doi.org/10.1016/j.ijbiomac.2020.07.029" @default.
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