Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040178491> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W3040178491 endingPage "273" @default.
- W3040178491 startingPage "272" @default.
- W3040178491 abstract "Strand separation in double stranded DNA is achieved in vivo by a class of enzymes called helicases in a process fuelled by hydrolysis of nucleoside triphosphates. DnaB is the major replicative helicase in E.coli. For chromosomal replication to initiate, DnaB needs to interact with a partner protein, namely DnaC, which after properly loading DnaB onto the DNA template at the origin of replication is subsequently released from the complex. DnaB turns to be functionally active as a helicase only after DnaC has been released from the complex. The native DnaB is a homohexamer of molecular weight 318 kD. In the presence of ATP and Mg 2+ , the hexameric DnaB has been shown to form a complex with six molecules of DnaC (total molecular weight of the complex: 480 kD). The reconstructed 3D volume of the DnaB hexamer obtained from frozen-hydrated specimens showed the DnaB oligomer as a particle possessing three-fold rather than six-fold symmetry, despite DnaB being made up by six identical subunits." @default.
- W3040178491 created "2020-07-10" @default.
- W3040178491 creator A5003962825 @default.
- W3040178491 creator A5053679121 @default.
- W3040178491 creator A5056969847 @default.
- W3040178491 creator A5061849220 @default.
- W3040178491 creator A5090699749 @default.
- W3040178491 date "2000-08-01" @default.
- W3040178491 modified "2023-10-15" @default.
- W3040178491 title "Quaternary Polymorphism in Helicases and the DnaB.DnaC Complex" @default.
- W3040178491 cites W1995227830 @default.
- W3040178491 cites W2030903100 @default.
- W3040178491 cites W2065623919 @default.
- W3040178491 cites W2111241008 @default.
- W3040178491 cites W2135015314 @default.
- W3040178491 doi "https://doi.org/10.1017/s1431927600033857" @default.
- W3040178491 hasPublicationYear "2000" @default.
- W3040178491 type Work @default.
- W3040178491 sameAs 3040178491 @default.
- W3040178491 citedByCount "0" @default.
- W3040178491 crossrefType "journal-article" @default.
- W3040178491 hasAuthorship W3040178491A5003962825 @default.
- W3040178491 hasAuthorship W3040178491A5053679121 @default.
- W3040178491 hasAuthorship W3040178491A5056969847 @default.
- W3040178491 hasAuthorship W3040178491A5061849220 @default.
- W3040178491 hasAuthorship W3040178491A5090699749 @default.
- W3040178491 hasConcept C104317684 @default.
- W3040178491 hasConcept C116107829 @default.
- W3040178491 hasConcept C161223559 @default.
- W3040178491 hasConcept C185592680 @default.
- W3040178491 hasConcept C552990157 @default.
- W3040178491 hasConcept C55493867 @default.
- W3040178491 hasConcept C67705224 @default.
- W3040178491 hasConcept C86803240 @default.
- W3040178491 hasConceptScore W3040178491C104317684 @default.
- W3040178491 hasConceptScore W3040178491C116107829 @default.
- W3040178491 hasConceptScore W3040178491C161223559 @default.
- W3040178491 hasConceptScore W3040178491C185592680 @default.
- W3040178491 hasConceptScore W3040178491C552990157 @default.
- W3040178491 hasConceptScore W3040178491C55493867 @default.
- W3040178491 hasConceptScore W3040178491C67705224 @default.
- W3040178491 hasConceptScore W3040178491C86803240 @default.
- W3040178491 hasIssue "S2" @default.
- W3040178491 hasLocation W30401784911 @default.
- W3040178491 hasOpenAccess W3040178491 @default.
- W3040178491 hasPrimaryLocation W30401784911 @default.
- W3040178491 hasRelatedWork W1992394095 @default.
- W3040178491 hasRelatedWork W2009159101 @default.
- W3040178491 hasRelatedWork W2034175604 @default.
- W3040178491 hasRelatedWork W2047912381 @default.
- W3040178491 hasRelatedWork W2064311909 @default.
- W3040178491 hasRelatedWork W2127009315 @default.
- W3040178491 hasRelatedWork W2134225956 @default.
- W3040178491 hasRelatedWork W2154738159 @default.
- W3040178491 hasRelatedWork W2907592030 @default.
- W3040178491 hasRelatedWork W67216325 @default.
- W3040178491 hasVolume "6" @default.
- W3040178491 isParatext "false" @default.
- W3040178491 isRetracted "false" @default.
- W3040178491 magId "3040178491" @default.
- W3040178491 workType "article" @default.