FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040186019> ?p ?o ?g. }

• W3040186019 abstract "Abstract The fungal kingdom has been widely studied as a source of bioactive compounds of interest to the pharmaceutical and food industry. This paper studies the production of natural red pigments by Fusarium solani BRM054066 in the submerged fermentation system, using Doehlert experimental design to determine optimal cultivation conditions. The chemical composition of the red pigment was determined by Nuclear Magnetic Resonance spectroscopy (NMR) and Ultra-Performance Liquid Chromatography coupled to Mass Spectrometry (UPLC-MS). Antioxidant activity was assessed by the ability to sequester of free radical DPPH. In the analysis of anti-inflammatory activity, murine peritoneal macrophages activated by LPS were used, and the gene expression of TNF-α, IL-1β, IL-6, IL-10 and IL-17 was determined using qPCR. As a result, it was found that agitation at 200 rpm and glucose concentration ≥ 20 g/L promote the best results in the production of red pigment. The chemical compounds identified were two naphthoquinones, fusarubin and dihydrofusarubin, and an anthraquinone, a bostrycoidin, being fusarubin the majority compound. The red pigment showed antioxidant activity by scavenge 50% of the DPPH radical, in a concentration of 24 µg/mL. The pigment also showed an effective anti-inflammatory capacity by reducing the overexpression of the pro-inflammatory cytokines TNF-α, IL-1β and IL-6 and promoting the production of anti-inflammatory IL-10 and IL-17, in murine macrophages activated by LPS (p < 0.05). According to the results, the fungus F. solani BRM054066, under optimized conditions of cultivation, proved to be a promising source of biologically active natural pigments with wide industrial applicability." @default.
• W3040186019 created "2020-07-10" @default.
• W3040186019 creator A5001953091 @default.
• W3040186019 creator A5006288012 @default.
• W3040186019 creator A5008085257 @default.
• W3040186019 creator A5019949022 @default.
• W3040186019 creator A5022127168 @default.
• W3040186019 creator A5031781033 @default.
• W3040186019 creator A5042720791 @default.
• W3040186019 creator A5045500674 @default.
• W3040186019 creator A5065032589 @default.
• W3040186019 creator A5080672449 @default.
• W3040186019 date "2020-07-01" @default.
• W3040186019 modified "2023-09-25" @default.
• W3040186019 title "Pigment production by Fusarium solani BRM054066 and determination of antioxidant and anti-inflammatory properties" @default.
• W3040186019 cites W1809721560 @default.
• W3040186019 cites W1963554147 @default.
• W3040186019 cites W1968166882 @default.
• W3040186019 cites W1986521743 @default.
• W3040186019 cites W1988378772 @default.
• W3040186019 cites W1994910441 @default.
• W3040186019 cites W2003160601 @default.
• W3040186019 cites W2003597028 @default.
• W3040186019 cites W2003777700 @default.
• W3040186019 cites W2004611644 @default.
• W3040186019 cites W2006836695 @default.
• W3040186019 cites W2011550240 @default.
• W3040186019 cites W2017955689 @default.
• W3040186019 cites W2018538029 @default.
• W3040186019 cites W2027095513 @default.
• W3040186019 cites W2028644279 @default.
• W3040186019 cites W2032576320 @default.
• W3040186019 cites W2033898136 @default.
• W3040186019 cites W2037181094 @default.
• W3040186019 cites W2041057624 @default.
• W3040186019 cites W2060115434 @default.
• W3040186019 cites W2065853716 @default.
• W3040186019 cites W2069793509 @default.
• W3040186019 cites W2079844514 @default.
• W3040186019 cites W2081813808 @default.
• W3040186019 cites W2107620965 @default.
• W3040186019 cites W2108453281 @default.
• W3040186019 cites W2116904877 @default.
• W3040186019 cites W2119716198 @default.
• W3040186019 cites W2143046674 @default.
• W3040186019 cites W2145180842 @default.
• W3040186019 cites W2302177346 @default.
• W3040186019 cites W2338689244 @default.
• W3040186019 cites W2404956312 @default.
• W3040186019 cites W2509872912 @default.
• W3040186019 cites W2524571528 @default.
• W3040186019 cites W2533510557 @default.
• W3040186019 cites W2553543541 @default.
• W3040186019 cites W2570879358 @default.
• W3040186019 cites W2572261390 @default.
• W3040186019 cites W2584318221 @default.
• W3040186019 cites W2592508758 @default.
• W3040186019 cites W2614542690 @default.
• W3040186019 cites W2621703972 @default.
• W3040186019 cites W2740384383 @default.
• W3040186019 cites W2889732988 @default.
• W3040186019 cites W2895584672 @default.
• W3040186019 cites W3142093494 @default.
• W3040186019 cites W8283006 @default.
• W3040186019 doi "https://doi.org/10.1186/s13568-020-01054-y" @default.
• W3040186019 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7329961" @default.
• W3040186019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32613282" @default.
• W3040186019 hasPublicationYear "2020" @default.
• W3040186019 type Work @default.
• W3040186019 sameAs 3040186019 @default.
• W3040186019 citedByCount "10" @default.
• W3040186019 countsByYear W30401860192021 @default.
• W3040186019 countsByYear W30401860192022 @default.
• W3040186019 countsByYear W30401860192023 @default.
• W3040186019 crossrefType "journal-article" @default.
• W3040186019 hasAuthorship W3040186019A5001953091 @default.
• W3040186019 hasAuthorship W3040186019A5006288012 @default.
• W3040186019 hasAuthorship W3040186019A5008085257 @default.
• W3040186019 hasAuthorship W3040186019A5019949022 @default.
• W3040186019 hasAuthorship W3040186019A5022127168 @default.
• W3040186019 hasAuthorship W3040186019A5031781033 @default.
• W3040186019 hasAuthorship W3040186019A5042720791 @default.
• W3040186019 hasAuthorship W3040186019A5045500674 @default.
• W3040186019 hasAuthorship W3040186019A5065032589 @default.
• W3040186019 hasAuthorship W3040186019A5080672449 @default.
• W3040186019 hasBestOaLocation W30401860191 @default.
• W3040186019 hasConcept C100544194 @default.
• W3040186019 hasConcept C178790620 @default.
• W3040186019 hasConcept C185592680 @default.
• W3040186019 hasConcept C2778004101 @default.
• W3040186019 hasConcept C2778342517 @default.
• W3040186019 hasConcept C2779703632 @default.
• W3040186019 hasConcept C2781401929 @default.
• W3040186019 hasConcept C31903555 @default.
• W3040186019 hasConcept C43617362 @default.
• W3040186019 hasConcept C55493867 @default.
• W3040186019 hasConcept C59822182 @default.
• W3040186019 hasConcept C64584667 @default.
• W3040186019 hasConcept C86803240 @default.
• W3040186019 hasConcept C98274493 @default.

• next