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- W3040197336 abstract "Abstract tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or precursor tRNAs. tRFs and tiRNAs play biological roles through a variety of mechanisms by interacting with proteins or mRNA, inhibiting translation, and regulating gene expression, the cell cycle, and chromatin and epigenetic modifications. The establishment and application of research technologies are important in understanding the biological roles of tRFs and tiRNAs. To study the molecular mechanisms of tRFs and tiRNAs, researchers have used a variety of bioinformatics and molecular biology methods, such as microarray analysis, real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR); Northern blotting; RNA sequencing (RNA-seq); cross-linking, ligation and sequencing of hybrids (CLASH); and photoactivatable-ribonucleoside-enhanced cross-linking and immunoprecipitation (PAR-CLIP). This paper summarizes the classification, action mechanisms, and roles of tRFs and tiRNAs in human diseases and the related signal transduction pathways, targeted therapies, databases, and research methods associated with them." @default.
- W3040197336 created "2020-07-10" @default.
- W3040197336 creator A5023826377 @default.
- W3040197336 creator A5044988706 @default.
- W3040197336 creator A5048078319 @default.
- W3040197336 creator A5048939071 @default.
- W3040197336 creator A5050471394 @default.
- W3040197336 creator A5061921642 @default.
- W3040197336 date "2020-06-30" @default.
- W3040197336 modified "2023-10-16" @default.
- W3040197336 title "Action mechanisms and research methods of tRNA-derived small RNAs" @default.
- W3040197336 cites W1440386396 @default.
- W3040197336 cites W1832399013 @default.
- W3040197336 cites W1944804641 @default.
- W3040197336 cites W1988153625 @default.
- W3040197336 cites W1995975529 @default.
- W3040197336 cites W2000993455 @default.
- W3040197336 cites W2004791359 @default.
- W3040197336 cites W2005625535 @default.
- W3040197336 cites W2007615447 @default.
- W3040197336 cites W2008255393 @default.
- W3040197336 cites W2020408643 @default.
- W3040197336 cites W2021599506 @default.
- W3040197336 cites W2029410145 @default.
- W3040197336 cites W2032200822 @default.
- W3040197336 cites W2056831129 @default.
- W3040197336 cites W2058661925 @default.
- W3040197336 cites W2065129911 @default.
- W3040197336 cites W2067022150 @default.
- W3040197336 cites W2069799979 @default.
- W3040197336 cites W2076772609 @default.
- W3040197336 cites W2093956979 @default.
- W3040197336 cites W2099766566 @default.
- W3040197336 cites W2100966665 @default.
- W3040197336 cites W2106039274 @default.
- W3040197336 cites W2112061715 @default.
- W3040197336 cites W2113666425 @default.
- W3040197336 cites W2115688236 @default.
- W3040197336 cites W2120138069 @default.
- W3040197336 cites W2124200821 @default.
- W3040197336 cites W2142584500 @default.
- W3040197336 cites W2148224382 @default.
- W3040197336 cites W2149403492 @default.
- W3040197336 cites W2158403894 @default.
- W3040197336 cites W2164256634 @default.
- W3040197336 cites W2169694864 @default.
- W3040197336 cites W2195136000 @default.
- W3040197336 cites W2201382378 @default.
- W3040197336 cites W2210080033 @default.
- W3040197336 cites W2234681847 @default.
- W3040197336 cites W2303912045 @default.
- W3040197336 cites W2338525238 @default.
- W3040197336 cites W2342252259 @default.
- W3040197336 cites W2354695783 @default.
- W3040197336 cites W2357230789 @default.
- W3040197336 cites W2417123930 @default.
- W3040197336 cites W2475184562 @default.
- W3040197336 cites W2510348945 @default.
- W3040197336 cites W2554225141 @default.
- W3040197336 cites W2557484630 @default.
- W3040197336 cites W2582898297 @default.
- W3040197336 cites W2584102880 @default.
- W3040197336 cites W2605223191 @default.
- W3040197336 cites W2608110242 @default.
- W3040197336 cites W2734686459 @default.
- W3040197336 cites W2751526023 @default.
- W3040197336 cites W2762767363 @default.
- W3040197336 cites W2769912973 @default.
- W3040197336 cites W2774031974 @default.
- W3040197336 cites W2792636075 @default.
- W3040197336 cites W2793450872 @default.
- W3040197336 cites W2795813366 @default.
- W3040197336 cites W2802787795 @default.
- W3040197336 cites W2806435205 @default.
- W3040197336 cites W2888576209 @default.
- W3040197336 cites W2889199113 @default.
- W3040197336 cites W2890244942 @default.
- W3040197336 cites W2891388080 @default.
- W3040197336 cites W2898200756 @default.
- W3040197336 cites W2905137290 @default.
- W3040197336 cites W2920294775 @default.
- W3040197336 cites W2924349232 @default.
- W3040197336 cites W2930157042 @default.
- W3040197336 cites W2937316677 @default.
- W3040197336 cites W2939643004 @default.
- W3040197336 cites W2945544309 @default.
- W3040197336 cites W2957041352 @default.
- W3040197336 cites W2967315044 @default.
- W3040197336 cites W2971135467 @default.
- W3040197336 cites W2974337496 @default.
- W3040197336 cites W2978006966 @default.
- W3040197336 cites W2979574761 @default.
- W3040197336 cites W2989589482 @default.
- W3040197336 cites W2992839032 @default.
- W3040197336 cites W2995403614 @default.
- W3040197336 cites W2999749638 @default.
- W3040197336 cites W3000230762 @default.
- W3040197336 cites W3003453550 @default.
- W3040197336 cites W3004267120 @default.
- W3040197336 cites W3008851099 @default.