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- W3040227612 abstract "Only few studies have yet investigated whether perioperative administration of pregabalin can reduce the incidence of postoperative chronic neuropathic pain after total hip arthroplasty (THA). This prospective, randomized study compared placebo with pregabalin in the hope that a lower pregabalin dose would improve analgesia without increasing side-effects after THA.This study was a prospective randomized blinded study, with a parallel design and an allocation ratio of 1:1 for the treatment groups. The study was approved by the Institutional Review Board in Weifang People's Hospital and written informed consent was obtained from all subjects before enrolment. A total of 120 patients who meet inclusion criteria are randomized to either pregabalin or placebo group. The primary objective of the study was visual analog scale score. As secondary outcomes, opioid consumption measurement, Harris Hip Score, hip range of motion, patient satisfaction, and complications were made at different time points throughout the study for comparison.The null hypothesis of this study was that pregabalin would reduce pain after THA.This study protocol was registered in Research Registry (researchregistry5669)." @default.
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- W3040227612 date "2020-07-02" @default.
- W3040227612 modified "2023-09-27" @default.
- W3040227612 title "The analgesic efficiency of pregabalin for the treatment of postoperative pain in total hip arthroplasty" @default.
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- W3040227612 doi "https://doi.org/10.1097/md.0000000000021071" @default.
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