Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040240140> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W3040240140 endingPage "1161" @default.
- W3040240140 startingPage "1160" @default.
- W3040240140 abstract "Upon thrombin-catalyzed proteolytic conversion of fibrinogen to fibrin, fibrinopeptide A release exposes an N-terminal polymerization site (‘E A ’) in the central E domain that interacts with a constitutive complementary site in each outer D domain (‘D a ’) to drive the molecular assembly process by end-to-middle domain non-covalent ‘D a :E A ’ interactions. End-to-end aligned doublestranded fibrils are formed in coordination with another recently described constitutive self-association site (termed ‘D:D’)that is situated at the outer end of each D domain. The D:D site contributes to end-to-end molecular alignment of fibrin molecules within each fibril strand. Concomitant branching and lateral fibril associations to form thick fibers, lead to formation of the mature fibrin clot. Fibrinogen ‘Kurashiki’ is a unique congenital dysfibrinogenemia that was identified in a homozygous father and his heterozygous son. The abnormality involves a γ chain amino acid mutation (γ G268E) and is characterized by delayed and abnormal fibrin polymerization." @default.
- W3040240140 created "2020-07-10" @default.
- W3040240140 creator A5072205946 @default.
- W3040240140 creator A5073314507 @default.
- W3040240140 creator A5086547501 @default.
- W3040240140 date "1998-07-01" @default.
- W3040240140 modified "2023-09-25" @default.
- W3040240140 title "Fibrinogen Kurashiki (γ G268E) Fibrin Network Structure" @default.
- W3040240140 cites W2028047806 @default.
- W3040240140 cites W2066217822 @default.
- W3040240140 cites W2295124736 @default.
- W3040240140 cites W2400436506 @default.
- W3040240140 doi "https://doi.org/10.1017/s1431927600025927" @default.
- W3040240140 hasPublicationYear "1998" @default.
- W3040240140 type Work @default.
- W3040240140 sameAs 3040240140 @default.
- W3040240140 citedByCount "0" @default.
- W3040240140 crossrefType "journal-article" @default.
- W3040240140 hasAuthorship W3040240140A5072205946 @default.
- W3040240140 hasAuthorship W3040240140A5073314507 @default.
- W3040240140 hasAuthorship W3040240140A5086547501 @default.
- W3040240140 hasConcept C12554922 @default.
- W3040240140 hasConcept C178790620 @default.
- W3040240140 hasConcept C185592680 @default.
- W3040240140 hasConcept C203014093 @default.
- W3040240140 hasConcept C27523624 @default.
- W3040240140 hasConcept C2777292125 @default.
- W3040240140 hasConcept C2779036427 @default.
- W3040240140 hasConcept C44228677 @default.
- W3040240140 hasConcept C521977710 @default.
- W3040240140 hasConcept C54173615 @default.
- W3040240140 hasConcept C55493867 @default.
- W3040240140 hasConcept C71240020 @default.
- W3040240140 hasConcept C86803240 @default.
- W3040240140 hasConcept C89560881 @default.
- W3040240140 hasConceptScore W3040240140C12554922 @default.
- W3040240140 hasConceptScore W3040240140C178790620 @default.
- W3040240140 hasConceptScore W3040240140C185592680 @default.
- W3040240140 hasConceptScore W3040240140C203014093 @default.
- W3040240140 hasConceptScore W3040240140C27523624 @default.
- W3040240140 hasConceptScore W3040240140C2777292125 @default.
- W3040240140 hasConceptScore W3040240140C2779036427 @default.
- W3040240140 hasConceptScore W3040240140C44228677 @default.
- W3040240140 hasConceptScore W3040240140C521977710 @default.
- W3040240140 hasConceptScore W3040240140C54173615 @default.
- W3040240140 hasConceptScore W3040240140C55493867 @default.
- W3040240140 hasConceptScore W3040240140C71240020 @default.
- W3040240140 hasConceptScore W3040240140C86803240 @default.
- W3040240140 hasConceptScore W3040240140C89560881 @default.
- W3040240140 hasIssue "S2" @default.
- W3040240140 hasLocation W30402401401 @default.
- W3040240140 hasOpenAccess W3040240140 @default.
- W3040240140 hasPrimaryLocation W30402401401 @default.
- W3040240140 hasRelatedWork W1907535191 @default.
- W3040240140 hasRelatedWork W1974152644 @default.
- W3040240140 hasRelatedWork W2025432833 @default.
- W3040240140 hasRelatedWork W2027230418 @default.
- W3040240140 hasRelatedWork W2029895043 @default.
- W3040240140 hasRelatedWork W2059104047 @default.
- W3040240140 hasRelatedWork W2076058780 @default.
- W3040240140 hasRelatedWork W2332777426 @default.
- W3040240140 hasRelatedWork W2422784750 @default.
- W3040240140 hasRelatedWork W4296715064 @default.
- W3040240140 hasVolume "4" @default.
- W3040240140 isParatext "false" @default.
- W3040240140 isRetracted "false" @default.
- W3040240140 magId "3040240140" @default.
- W3040240140 workType "article" @default.