Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040244491> ?p ?o ?g. }
- W3040244491 endingPage "468" @default.
- W3040244491 startingPage "456" @default.
- W3040244491 abstract "The lack of long-term patency of synthetic vascular grafts currently available on the market has directed research towards improving the performance of small diameter grafts. Improved radial compliance matching and tissue ingrowth into the graft scaffold are amongst the main goals for an ideal vascular graft. Biostable polyurethane scaffolds were manufactured by electrospinning and implanted in subcutaneous and circulatory positions in the rat for 7, 14 and 28 days. Scaffold morphology, tissue ingrowth, and mechanical properties of the scaffolds were assessed before implantation and after retrieval. Tissue ingrowth after 24 days was 96.5 ± 2.3% in the subcutaneous implants and 77.8 ± 5.4% in the circulatory implants. Over the 24 days implantation, the elastic modulus at 12% strain decreased by 59% in direction of the fibre alignment whereas it increased by 1379% transverse to the fibre alignment of the highly aligned scaffold of the subcutaneous implants. The lesser aligned scaffold of the circulatory graft implants exhibited an increase of the elastic modulus at 12% strain by 77% in circumferential direction. Based on the observations, it is proposed that the mechanism underlying the softening of the highly aligned scaffold in the predominant fibre direction is associated with scaffold compaction and local displacement of fibres by the newly formed tissue. The stiffening of the scaffold, observed transverse to highly aligned fibres and for more a random fibre distribution, represents the actual mechanical contribution of the tissue that developed in the scaffold." @default.
- W3040244491 created "2020-07-10" @default.
- W3040244491 creator A5000077575 @default.
- W3040244491 creator A5000651728 @default.
- W3040244491 creator A5004827011 @default.
- W3040244491 creator A5011316789 @default.
- W3040244491 creator A5012188406 @default.
- W3040244491 creator A5040913624 @default.
- W3040244491 creator A5084310182 @default.
- W3040244491 creator A5086745972 @default.
- W3040244491 date "2020-07-01" @default.
- W3040244491 modified "2023-09-25" @default.
- W3040244491 title "Tissue Ingrowth Markedly Reduces Mechanical Anisotropy and Stiffness in Fibre Direction of Highly Aligned Electrospun Polyurethane Scaffolds" @default.
- W3040244491 cites W1574341421 @default.
- W3040244491 cites W1933042345 @default.
- W3040244491 cites W1936953447 @default.
- W3040244491 cites W1966056673 @default.
- W3040244491 cites W1966550129 @default.
- W3040244491 cites W1974493691 @default.
- W3040244491 cites W1986684699 @default.
- W3040244491 cites W1991085301 @default.
- W3040244491 cites W1995489467 @default.
- W3040244491 cites W2014593879 @default.
- W3040244491 cites W2023166500 @default.
- W3040244491 cites W2028642482 @default.
- W3040244491 cites W2037703450 @default.
- W3040244491 cites W2044173810 @default.
- W3040244491 cites W2054294448 @default.
- W3040244491 cites W2055696984 @default.
- W3040244491 cites W2060358623 @default.
- W3040244491 cites W2061073729 @default.
- W3040244491 cites W2065895011 @default.
- W3040244491 cites W2066208282 @default.
- W3040244491 cites W2158670726 @default.
- W3040244491 cites W2164783843 @default.
- W3040244491 cites W2167279371 @default.
- W3040244491 cites W2187326531 @default.
- W3040244491 cites W2581866972 @default.
- W3040244491 cites W2589722423 @default.
- W3040244491 cites W2907149821 @default.
- W3040244491 doi "https://doi.org/10.1007/s13239-020-00475-x" @default.
- W3040244491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32613599" @default.
- W3040244491 hasPublicationYear "2020" @default.
- W3040244491 type Work @default.
- W3040244491 sameAs 3040244491 @default.
- W3040244491 citedByCount "2" @default.
- W3040244491 countsByYear W30402444912020 @default.
- W3040244491 crossrefType "journal-article" @default.
- W3040244491 hasAuthorship W3040244491A5000077575 @default.
- W3040244491 hasAuthorship W3040244491A5000651728 @default.
- W3040244491 hasAuthorship W3040244491A5004827011 @default.
- W3040244491 hasAuthorship W3040244491A5011316789 @default.
- W3040244491 hasAuthorship W3040244491A5012188406 @default.
- W3040244491 hasAuthorship W3040244491A5040913624 @default.
- W3040244491 hasAuthorship W3040244491A5084310182 @default.
- W3040244491 hasAuthorship W3040244491A5086745972 @default.
- W3040244491 hasBestOaLocation W30402444912 @default.
- W3040244491 hasConcept C136229726 @default.
- W3040244491 hasConcept C144796933 @default.
- W3040244491 hasConcept C159985019 @default.
- W3040244491 hasConcept C192562407 @default.
- W3040244491 hasConcept C193867417 @default.
- W3040244491 hasConcept C2779372316 @default.
- W3040244491 hasConcept C2779578285 @default.
- W3040244491 hasConcept C49892992 @default.
- W3040244491 hasConcept C521977710 @default.
- W3040244491 hasConcept C71924100 @default.
- W3040244491 hasConcept C89429830 @default.
- W3040244491 hasConceptScore W3040244491C136229726 @default.
- W3040244491 hasConceptScore W3040244491C144796933 @default.
- W3040244491 hasConceptScore W3040244491C159985019 @default.
- W3040244491 hasConceptScore W3040244491C192562407 @default.
- W3040244491 hasConceptScore W3040244491C193867417 @default.
- W3040244491 hasConceptScore W3040244491C2779372316 @default.
- W3040244491 hasConceptScore W3040244491C2779578285 @default.
- W3040244491 hasConceptScore W3040244491C49892992 @default.
- W3040244491 hasConceptScore W3040244491C521977710 @default.
- W3040244491 hasConceptScore W3040244491C71924100 @default.
- W3040244491 hasConceptScore W3040244491C89429830 @default.
- W3040244491 hasFunder F4320312677 @default.
- W3040244491 hasFunder F4320320671 @default.
- W3040244491 hasFunder F4320320672 @default.
- W3040244491 hasFunder F4320323555 @default.
- W3040244491 hasIssue "4" @default.
- W3040244491 hasLocation W30402444911 @default.
- W3040244491 hasLocation W30402444912 @default.
- W3040244491 hasLocation W30402444913 @default.
- W3040244491 hasOpenAccess W3040244491 @default.
- W3040244491 hasPrimaryLocation W30402444911 @default.
- W3040244491 hasRelatedWork W1016534219 @default.
- W3040244491 hasRelatedWork W1544035889 @default.
- W3040244491 hasRelatedWork W1979097177 @default.
- W3040244491 hasRelatedWork W2001610816 @default.
- W3040244491 hasRelatedWork W2053730842 @default.
- W3040244491 hasRelatedWork W2071568063 @default.
- W3040244491 hasRelatedWork W2362484625 @default.
- W3040244491 hasRelatedWork W2791240372 @default.
- W3040244491 hasRelatedWork W2912452346 @default.