FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040348840> ?p ?o ?g. }

• W3040348840 endingPage "3672" @default.
• W3040348840 startingPage "3664" @default.
• W3040348840 abstract "Abstract A series of 2‐amino‐5,6,7,8‐tetrahydro‐4H‐cyclohepta[b]thiophene‐3‐carboxamide‐heterocyclic hybrids were synthesized, characterized and their cytotoxic potencies were assessed on four human cell lines. Cyanoacetamide derivative ( 5 ) was used as the key synthetic intermediate for the synthesis many derivatives in this study, derivatives 9 , 11 , 12 were formed by coupled compound 5 with different aryl/heteryl diazonium chlorides, Gewald reaction and Knoevenagel condensation were used for synthesis derivatives 13 , 14 , 16 by treated cyanoacetamide ( 5 ) with different reagents. In another route, compound 5 treated with phenyl isothiocyanate give thiocarbamoyl derivative ( 7 ) which used as intermediate underwent oxidative cyclization with different moieties to offer the corresponding thiazoles and thiophene 18 , 19 , 20 , 21 , respectively. in vitro cytotoxic activity of prepared compounds were tested against four human tumor cell lines. The result revealed that compound 11a displayed promising cytotoxic activity against HepG2, HCT‐116, MCF‐7, and PC3 cancer cell lines comparing to the positive control (Doxorubicin)." @default.
• W3040348840 created "2020-07-10" @default.
• W3040348840 creator A5031570001 @default.
• W3040348840 creator A5047801145 @default.
• W3040348840 creator A5090668923 @default.
• W3040348840 date "2020-08-11" @default.
• W3040348840 modified "2023-10-18" @default.
• W3040348840 title "Synthesis and cytotoxic activity of some new heterocycles incorporating cyclohepta[b]thiophene‐3‐carboxamide derivatives" @default.
• W3040348840 cites W1555648817 @default.
• W3040348840 cites W1686251453 @default.
• W3040348840 cites W1973719140 @default.
• W3040348840 cites W1979547872 @default.
• W3040348840 cites W1991871496 @default.
• W3040348840 cites W2021628928 @default.
• W3040348840 cites W2027624502 @default.
• W3040348840 cites W2027669300 @default.
• W3040348840 cites W2041051161 @default.
• W3040348840 cites W2092601148 @default.
• W3040348840 cites W2123152169 @default.
• W3040348840 cites W2124095588 @default.
• W3040348840 cites W2140556264 @default.
• W3040348840 cites W2175889513 @default.
• W3040348840 cites W2178559495 @default.
• W3040348840 cites W2312679410 @default.
• W3040348840 cites W2340285439 @default.
• W3040348840 cites W2551936398 @default.
• W3040348840 cites W2914921318 @default.
• W3040348840 cites W2953334499 @default.
• W3040348840 cites W2963313586 @default.
• W3040348840 cites W2977951699 @default.
• W3040348840 cites W2998639463 @default.
• W3040348840 doi "https://doi.org/10.1002/jhet.4085" @default.
• W3040348840 hasPublicationYear "2020" @default.
• W3040348840 type Work @default.
• W3040348840 sameAs 3040348840 @default.
• W3040348840 citedByCount "7" @default.
• W3040348840 countsByYear W30403488402022 @default.
• W3040348840 countsByYear W30403488402023 @default.
• W3040348840 crossrefType "journal-article" @default.
• W3040348840 hasAuthorship W3040348840A5031570001 @default.
• W3040348840 hasAuthorship W3040348840A5047801145 @default.
• W3040348840 hasAuthorship W3040348840A5090668923 @default.
• W3040348840 hasConcept C106159729 @default.
• W3040348840 hasConcept C111771559 @default.
• W3040348840 hasConcept C114373084 @default.
• W3040348840 hasConcept C154317977 @default.
• W3040348840 hasConcept C155647269 @default.
• W3040348840 hasConcept C161790260 @default.
• W3040348840 hasConcept C162324750 @default.
• W3040348840 hasConcept C168395250 @default.
• W3040348840 hasConcept C178790620 @default.
• W3040348840 hasConcept C185592680 @default.
• W3040348840 hasConcept C202751555 @default.
• W3040348840 hasConcept C21951064 @default.
• W3040348840 hasConcept C2776568683 @default.
• W3040348840 hasConcept C2776572452 @default.
• W3040348840 hasConcept C2776878799 @default.
• W3040348840 hasConcept C2778327999 @default.
• W3040348840 hasConcept C2779953032 @default.
• W3040348840 hasConcept C2780263894 @default.
• W3040348840 hasConcept C2781076698 @default.
• W3040348840 hasConcept C40875361 @default.
• W3040348840 hasConcept C55493867 @default.
• W3040348840 hasConcept C71240020 @default.
• W3040348840 hasConceptScore W3040348840C106159729 @default.
• W3040348840 hasConceptScore W3040348840C111771559 @default.
• W3040348840 hasConceptScore W3040348840C114373084 @default.
• W3040348840 hasConceptScore W3040348840C154317977 @default.
• W3040348840 hasConceptScore W3040348840C155647269 @default.
• W3040348840 hasConceptScore W3040348840C161790260 @default.
• W3040348840 hasConceptScore W3040348840C162324750 @default.
• W3040348840 hasConceptScore W3040348840C168395250 @default.
• W3040348840 hasConceptScore W3040348840C178790620 @default.
• W3040348840 hasConceptScore W3040348840C185592680 @default.
• W3040348840 hasConceptScore W3040348840C202751555 @default.
• W3040348840 hasConceptScore W3040348840C21951064 @default.
• W3040348840 hasConceptScore W3040348840C2776568683 @default.
• W3040348840 hasConceptScore W3040348840C2776572452 @default.
• W3040348840 hasConceptScore W3040348840C2776878799 @default.
• W3040348840 hasConceptScore W3040348840C2778327999 @default.
• W3040348840 hasConceptScore W3040348840C2779953032 @default.
• W3040348840 hasConceptScore W3040348840C2780263894 @default.
• W3040348840 hasConceptScore W3040348840C2781076698 @default.
• W3040348840 hasConceptScore W3040348840C40875361 @default.
• W3040348840 hasConceptScore W3040348840C55493867 @default.
• W3040348840 hasConceptScore W3040348840C71240020 @default.
• W3040348840 hasIssue "10" @default.
• W3040348840 hasLocation W30403488401 @default.
• W3040348840 hasOpenAccess W3040348840 @default.
• W3040348840 hasPrimaryLocation W30403488401 @default.
• W3040348840 hasRelatedWork W1979213907 @default.
• W3040348840 hasRelatedWork W1983437237 @default.
• W3040348840 hasRelatedWork W2008379354 @default.
• W3040348840 hasRelatedWork W2279231442 @default.
• W3040348840 hasRelatedWork W2330835763 @default.
• W3040348840 hasRelatedWork W2574516770 @default.
• W3040348840 hasRelatedWork W2767333537 @default.
• W3040348840 hasRelatedWork W2999139619 @default.

• next