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- W3040574802 endingPage "2989" @default.
- W3040574802 startingPage "2989" @default.
- W3040574802 abstract "Artificial metalloenzymes (ArMs) comprise a synthetic metal complex in a protein scaffold. ArMs display performances combining those of both homogeneous catalysts and biocatalysts. Specifically, ArMs selectively catalyze non-natural reactions and reactions inspired by nature in water under mild conditions. In the past few years, the construction of ArMs that possess a genetically incorporated unnatural amino acid and the directed evolution of ArMs have become of great interest in the field. Additionally, biochemical applications of ArMs have steadily increased, owing to the fact that compartmentalization within a protein scaffold allows the synthetic metal complex to remain functional in a sea of inactivating biomolecules. In this review, we present updates on: (1) the newly reported ArMs, according to their type of reaction, and (2) the unique biochemical applications of ArMs, including chemoenzymatic cascades and intracellular/in vivo catalysis. We believe that ArMs have great potential as catalysts for organic synthesis and as chemical biology tools for pharmaceutical applications." @default.
- W3040574802 created "2020-07-10" @default.
- W3040574802 creator A5032298702 @default.
- W3040574802 creator A5090472475 @default.
- W3040574802 date "2020-06-30" @default.
- W3040574802 modified "2023-09-23" @default.
- W3040574802 title "Artificial Metalloenzymes: From Selective Chemical Transformations to Biochemical Applications" @default.
- W3040574802 cites W1031680929 @default.
- W3040574802 cites W1556223086 @default.
- W3040574802 cites W1598189694 @default.
- W3040574802 cites W1954202239 @default.
- W3040574802 cites W1969491778 @default.
- W3040574802 cites W1971948710 @default.
- W3040574802 cites W1972257010 @default.
- W3040574802 cites W1975182459 @default.
- W3040574802 cites W1975577823 @default.
- W3040574802 cites W1982400916 @default.
- W3040574802 cites W1984180361 @default.
- W3040574802 cites W1987455717 @default.
- W3040574802 cites W1989195247 @default.
- W3040574802 cites W1994729905 @default.
- W3040574802 cites W1996629685 @default.
- W3040574802 cites W2005871028 @default.
- W3040574802 cites W2012028316 @default.
- W3040574802 cites W2014280607 @default.
- W3040574802 cites W2017479817 @default.
- W3040574802 cites W2018132271 @default.
- W3040574802 cites W2033731839 @default.
- W3040574802 cites W2044942392 @default.
- W3040574802 cites W2063020466 @default.
- W3040574802 cites W2072618119 @default.
- W3040574802 cites W2076402046 @default.
- W3040574802 cites W2085277655 @default.
- W3040574802 cites W2099282718 @default.
- W3040574802 cites W2104968114 @default.
- W3040574802 cites W2109194451 @default.
- W3040574802 cites W2110260818 @default.
- W3040574802 cites W2110614767 @default.
- W3040574802 cites W2116594337 @default.
- W3040574802 cites W2118076612 @default.
- W3040574802 cites W2118363414 @default.
- W3040574802 cites W2119414767 @default.
- W3040574802 cites W2122623183 @default.
- W3040574802 cites W2130793963 @default.
- W3040574802 cites W2135598762 @default.
- W3040574802 cites W2139607159 @default.
- W3040574802 cites W2148313902 @default.
- W3040574802 cites W2150325934 @default.
- W3040574802 cites W2161149444 @default.
- W3040574802 cites W2170660601 @default.
- W3040574802 cites W2176845456 @default.
- W3040574802 cites W2197954584 @default.
- W3040574802 cites W2217153683 @default.
- W3040574802 cites W2302054269 @default.
- W3040574802 cites W2330974483 @default.
- W3040574802 cites W2340795529 @default.
- W3040574802 cites W2342711514 @default.
- W3040574802 cites W2412078865 @default.
- W3040574802 cites W2464204634 @default.
- W3040574802 cites W2482495999 @default.
- W3040574802 cites W2507192932 @default.
- W3040574802 cites W2513089562 @default.
- W3040574802 cites W2514385170 @default.
- W3040574802 cites W2518107319 @default.
- W3040574802 cites W2529265994 @default.
- W3040574802 cites W2554528613 @default.
- W3040574802 cites W2561201681 @default.
- W3040574802 cites W2594036425 @default.
- W3040574802 cites W2598457036 @default.
- W3040574802 cites W2601660355 @default.
- W3040574802 cites W2613083880 @default.
- W3040574802 cites W2613889112 @default.
- W3040574802 cites W2650052967 @default.
- W3040574802 cites W2735208100 @default.
- W3040574802 cites W2735839143 @default.
- W3040574802 cites W2742698293 @default.
- W3040574802 cites W2753393433 @default.
- W3040574802 cites W2763278454 @default.
- W3040574802 cites W2765583288 @default.
- W3040574802 cites W2766879408 @default.
- W3040574802 cites W2767044445 @default.
- W3040574802 cites W2768252314 @default.
- W3040574802 cites W2769735050 @default.
- W3040574802 cites W2770854189 @default.
- W3040574802 cites W2772531727 @default.
- W3040574802 cites W2781816855 @default.
- W3040574802 cites W2782246467 @default.
- W3040574802 cites W2783431238 @default.
- W3040574802 cites W2784128645 @default.
- W3040574802 cites W2785293120 @default.
- W3040574802 cites W2790867585 @default.
- W3040574802 cites W2791785373 @default.
- W3040574802 cites W2793209087 @default.
- W3040574802 cites W2800695561 @default.
- W3040574802 cites W2803730805 @default.
- W3040574802 cites W2804205785 @default.
- W3040574802 cites W2807067488 @default.
- W3040574802 cites W2808649653 @default.