FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040673624> ?p ?o ?g. }

• W3040673624 endingPage "16771" @default.
• W3040673624 startingPage "16762" @default.
• W3040673624 abstract "Thiolated self-assembled monolayers (SAMs) are typically used to anchor on a gold surface biomolecules serving as recognition elements for biosensor applications. Here, the design and synthesis of N-(2-hydroxyethyl)-3-mercaptopropanamide (NMPA) in biotinylated mixed SAMs is proposed as an alternative strategy with respect to on-site multistep functionalization of SAMs prepared from solutions of commercially available thiols. In this study, the mixed SAM deposited from a 10:1 solution of 3-mercaptopropionic acid (3MPA) and 11-mercaptoundecanoic acid (11MUA) is compared to that resulting from a 10:1 solution of NMPA:11MUA. To this end, surface plasmon resonance (SPR) and attenuated total reflectance infrared (ATR-IR) experiments have been carried out on both mixed SAMs after biotinylation. The study demonstrated how the fine tuning of the SAM features impacts directly on both the biofunctionalization steps, i.e., the biotin anchoring, and the biorecognition properties evaluated upon exposure to streptavidin analyte. Higher affinity for the target analyte with reduced nonspecific binding and lower detection limit has been demonstrated when NMPA is chosen as the more abundant starting thiol. Molecular dynamics simulations complemented the experimental findings providing a molecular rationale behind the performance of the biotinylated mixed SAMs. The present study confirms the importance of the functionalization design for the development of a highly performing biosensor." @default.
• W3040673624 created "2020-07-10" @default.
• W3040673624 creator A5005635608 @default.
• W3040673624 creator A5016720100 @default.
• W3040673624 creator A5016908432 @default.
• W3040673624 creator A5019357972 @default.
• W3040673624 creator A5024713963 @default.
• W3040673624 creator A5030339405 @default.
• W3040673624 creator A5048477086 @default.
• W3040673624 creator A5050080671 @default.
• W3040673624 creator A5063045793 @default.
• W3040673624 creator A5082290274 @default.
• W3040673624 creator A5090032081 @default.
• W3040673624 date "2020-07-01" @default.
• W3040673624 modified "2023-10-16" @default.
• W3040673624 title "Enhancing the Sensitivity of Biotinylated Surfaces by Tailoring the Design of the Mixed Self-Assembled Monolayer Synthesis" @default.
• W3040673624 cites W1203407591 @default.
• W3040673624 cites W1967049024 @default.
• W3040673624 cites W1967598238 @default.
• W3040673624 cites W1969730709 @default.
• W3040673624 cites W1971421725 @default.
• W3040673624 cites W1977453831 @default.
• W3040673624 cites W1984399151 @default.
• W3040673624 cites W1987533236 @default.
• W3040673624 cites W1991962456 @default.
• W3040673624 cites W1994894979 @default.
• W3040673624 cites W2001769045 @default.
• W3040673624 cites W2005926382 @default.
• W3040673624 cites W2008490838 @default.
• W3040673624 cites W2010016289 @default.
• W3040673624 cites W2010801401 @default.
• W3040673624 cites W2011437619 @default.
• W3040673624 cites W2011764801 @default.
• W3040673624 cites W2011956254 @default.
• W3040673624 cites W2014362134 @default.
• W3040673624 cites W2020820266 @default.
• W3040673624 cites W2034671474 @default.
• W3040673624 cites W2040932720 @default.
• W3040673624 cites W2041762213 @default.
• W3040673624 cites W2042386191 @default.
• W3040673624 cites W2043844942 @default.
• W3040673624 cites W2046484526 @default.
• W3040673624 cites W2054232817 @default.
• W3040673624 cites W2054345707 @default.
• W3040673624 cites W2057533860 @default.
• W3040673624 cites W2062216518 @default.
• W3040673624 cites W2069190985 @default.
• W3040673624 cites W2076502410 @default.
• W3040673624 cites W2084827916 @default.
• W3040673624 cites W2091019343 @default.
• W3040673624 cites W2101982331 @default.
• W3040673624 cites W2107208446 @default.
• W3040673624 cites W2120469859 @default.
• W3040673624 cites W2131485189 @default.
• W3040673624 cites W2132505490 @default.
• W3040673624 cites W2140311155 @default.
• W3040673624 cites W2150981663 @default.
• W3040673624 cites W2158175581 @default.
• W3040673624 cites W2166806803 @default.
• W3040673624 cites W2280474114 @default.
• W3040673624 cites W2322762600 @default.
• W3040673624 cites W2333584884 @default.
• W3040673624 cites W2339142012 @default.
• W3040673624 cites W2485687501 @default.
• W3040673624 cites W2580299194 @default.
• W3040673624 cites W2590814018 @default.
• W3040673624 cites W2623206576 @default.
• W3040673624 cites W2674153015 @default.
• W3040673624 cites W2780929833 @default.
• W3040673624 cites W2883714975 @default.
• W3040673624 cites W2887792985 @default.
• W3040673624 cites W2907912611 @default.
• W3040673624 cites W2930379825 @default.
• W3040673624 cites W2968330262 @default.
• W3040673624 cites W2971435914 @default.
• W3040673624 cites W2987155726 @default.
• W3040673624 cites W2994514299 @default.
• W3040673624 cites W2995767370 @default.
• W3040673624 doi "https://doi.org/10.1021/acsomega.0c01717" @default.
• W3040673624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7364725" @default.
• W3040673624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32685844" @default.
• W3040673624 hasPublicationYear "2020" @default.
• W3040673624 type Work @default.
• W3040673624 sameAs 3040673624 @default.
• W3040673624 citedByCount "20" @default.
• W3040673624 countsByYear W30406736242020 @default.
• W3040673624 countsByYear W30406736242021 @default.
• W3040673624 countsByYear W30406736242022 @default.
• W3040673624 countsByYear W30406736242023 @default.
• W3040673624 crossrefType "journal-article" @default.
• W3040673624 hasAuthorship W3040673624A5005635608 @default.
• W3040673624 hasAuthorship W3040673624A5016720100 @default.
• W3040673624 hasAuthorship W3040673624A5016908432 @default.
• W3040673624 hasAuthorship W3040673624A5019357972 @default.
• W3040673624 hasAuthorship W3040673624A5024713963 @default.
• W3040673624 hasAuthorship W3040673624A5030339405 @default.
• W3040673624 hasAuthorship W3040673624A5048477086 @default.
• W3040673624 hasAuthorship W3040673624A5050080671 @default.

• next