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- W3040701080 endingPage "127654" @default.
- W3040701080 startingPage "127654" @default.
- W3040701080 abstract "The emerging growth of nanotechnology has attracted great attention due to its application in the parasite and intermediate host control. However, the knowledge concerning the mechanism of action (MoA) and toxicity of nanomaterials (NMs) to snails remain unclear. In this context, the present study revised the historical use of snails as experimental models in nanotoxicological studies and summarized the MoA and toxicity of NMs in aquatic and land snails. The data concerning the bioaccumulation, reproductive and transgenerational toxicity, embryotoxicity, genotoxicity and potential molluscicidal activity of NMs were revised. Furthermore, the data about the experimental conditions, such as exposure time, concentrations, cell and tissue-specific responses, snail species and nanoparticle types are discussed. Revised data showed that the toxic effects of NMs were reported for 21 snail species with medical, veterinary and ecological importance. The NM toxicity to snails is dependent on the physical and chemical properties of NMs, as well as their environmental transformation and experimental design. The NM bioaccumulation on snails was related to several toxic effects, such as reactive oxygen species (ROS) production, oxidative stress, following by oxidative damage to DNA, lipids and proteins. The NM metabolism in snails remains unknown. Results showed the potential use of NMs in the snail control program. Also, significant research gaps and recommendations for future researches are indicated. The present study confirms that snails are suitable invertebrate model system to assess the nanotoxicity." @default.
- W3040701080 created "2020-07-16" @default.
- W3040701080 creator A5020584804 @default.
- W3040701080 creator A5022587822 @default.
- W3040701080 creator A5023342685 @default.
- W3040701080 creator A5066369940 @default.
- W3040701080 creator A5072988479 @default.
- W3040701080 creator A5086062711 @default.
- W3040701080 date "2020-12-01" @default.
- W3040701080 modified "2023-09-24" @default.
- W3040701080 title "Toxicity of engineered nanomaterials to aquatic and land snails: A scientometric and systematic review" @default.
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