Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040737675> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3040737675 abstract "It has been established that the innate and adaptive immune suppression was heterogeneous in septic and nonseptic critically ill patients, while the value of immune function in pediatric patients with nonseptic critical illness is limited. We conducted a single-center retrospective study to explore this issue. A total of 65 children with nonseptic illnesses were studied for lymphocyte subpopulations, immunoglobulin concentrations, complement concentrations, and cytokines in peripheral blood in the next 72 hours after admission to our Pediatric Intensive Care Unit (PICU). When compared to clinically recovered patients, patients with disease progression had a numerically lower but not significantly different median pediatric critical illness score and longer PICU median stays. The analysis of serum immunoglobulin (IgG, IgM, and IgA), serum complement (C3, C4) concentrations, and lymphocyte subpopulations showed no significantly difference between patients with and without relieved clinical symptoms by day 4. For the cytokine analysis, the level of IL-6 was significantly higher in patients with disease progression than that in patients who clinically recovered (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mn>0.046</mml:mn></mml:math>). In the univariate Cox regression analysis, plasma IL-6 levels were associated with outcome. Multivariate analysis evidenced that the level of plasma IL-6 was one of the factors determining the length of hospital stays. In conclusions, our results demonstrate that increased IL-6 levels in the initial 72 hours post admission are associated with prolonged stays and disease progression in nonseptic critically ill children in the PICU." @default.
- W3040737675 created "2020-07-16" @default.
- W3040737675 creator A5004934332 @default.
- W3040737675 creator A5030154710 @default.
- W3040737675 creator A5042252717 @default.
- W3040737675 creator A5077135144 @default.
- W3040737675 date "2020-07-10" @default.
- W3040737675 modified "2023-10-16" @default.
- W3040737675 title "Elevated Interleukin-6 Levels within 72 Hours Post Admission Are Associated with Disease Progression in Nonseptic Critically Ill Children" @default.
- W3040737675 cites W1494122660 @default.
- W3040737675 cites W1506666092 @default.
- W3040737675 cites W1981253514 @default.
- W3040737675 cites W2041783524 @default.
- W3040737675 cites W2079672406 @default.
- W3040737675 cites W2099368337 @default.
- W3040737675 cites W2118887012 @default.
- W3040737675 cites W2152955526 @default.
- W3040737675 cites W2257793589 @default.
- W3040737675 cites W2613494553 @default.
- W3040737675 cites W2766225476 @default.
- W3040737675 cites W2770293163 @default.
- W3040737675 cites W2792878487 @default.
- W3040737675 cites W2794334823 @default.
- W3040737675 cites W2794439091 @default.
- W3040737675 cites W2800188851 @default.
- W3040737675 cites W2803827892 @default.
- W3040737675 cites W2811287573 @default.
- W3040737675 cites W2943476675 @default.
- W3040737675 cites W2948938064 @default.
- W3040737675 cites W2971784664 @default.
- W3040737675 cites W4256705231 @default.
- W3040737675 doi "https://doi.org/10.1155/2020/4596851" @default.
- W3040737675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7368930" @default.
- W3040737675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32695814" @default.
- W3040737675 hasPublicationYear "2020" @default.
- W3040737675 type Work @default.
- W3040737675 sameAs 3040737675 @default.
- W3040737675 citedByCount "0" @default.
- W3040737675 crossrefType "journal-article" @default.
- W3040737675 hasAuthorship W3040737675A5004934332 @default.
- W3040737675 hasAuthorship W3040737675A5030154710 @default.
- W3040737675 hasAuthorship W3040737675A5042252717 @default.
- W3040737675 hasAuthorship W3040737675A5077135144 @default.
- W3040737675 hasBestOaLocation W30407376751 @default.
- W3040737675 hasConcept C111684460 @default.
- W3040737675 hasConcept C126322002 @default.
- W3040737675 hasConcept C144301174 @default.
- W3040737675 hasConcept C159654299 @default.
- W3040737675 hasConcept C177713679 @default.
- W3040737675 hasConcept C203014093 @default.
- W3040737675 hasConcept C2776376669 @default.
- W3040737675 hasConcept C2777761686 @default.
- W3040737675 hasConcept C2778690821 @default.
- W3040737675 hasConcept C2778939556 @default.
- W3040737675 hasConcept C2779134260 @default.
- W3040737675 hasConcept C38180746 @default.
- W3040737675 hasConcept C71924100 @default.
- W3040737675 hasConcept C8891405 @default.
- W3040737675 hasConcept C90924648 @default.
- W3040737675 hasConceptScore W3040737675C111684460 @default.
- W3040737675 hasConceptScore W3040737675C126322002 @default.
- W3040737675 hasConceptScore W3040737675C144301174 @default.
- W3040737675 hasConceptScore W3040737675C159654299 @default.
- W3040737675 hasConceptScore W3040737675C177713679 @default.
- W3040737675 hasConceptScore W3040737675C203014093 @default.
- W3040737675 hasConceptScore W3040737675C2776376669 @default.
- W3040737675 hasConceptScore W3040737675C2777761686 @default.
- W3040737675 hasConceptScore W3040737675C2778690821 @default.
- W3040737675 hasConceptScore W3040737675C2778939556 @default.
- W3040737675 hasConceptScore W3040737675C2779134260 @default.
- W3040737675 hasConceptScore W3040737675C38180746 @default.
- W3040737675 hasConceptScore W3040737675C71924100 @default.
- W3040737675 hasConceptScore W3040737675C8891405 @default.
- W3040737675 hasConceptScore W3040737675C90924648 @default.
- W3040737675 hasLocation W30407376751 @default.
- W3040737675 hasLocation W30407376752 @default.
- W3040737675 hasLocation W30407376753 @default.
- W3040737675 hasLocation W30407376754 @default.
- W3040737675 hasOpenAccess W3040737675 @default.
- W3040737675 hasPrimaryLocation W30407376751 @default.
- W3040737675 hasRelatedWork W1572283981 @default.
- W3040737675 hasRelatedWork W1993985418 @default.
- W3040737675 hasRelatedWork W2047209980 @default.
- W3040737675 hasRelatedWork W2056022494 @default.
- W3040737675 hasRelatedWork W3017248443 @default.
- W3040737675 hasRelatedWork W3048051248 @default.
- W3040737675 hasRelatedWork W3124424147 @default.
- W3040737675 hasRelatedWork W3215105073 @default.
- W3040737675 hasRelatedWork W2185732136 @default.
- W3040737675 hasRelatedWork W2396811992 @default.
- W3040737675 isParatext "false" @default.
- W3040737675 isRetracted "false" @default.
- W3040737675 magId "3040737675" @default.
- W3040737675 workType "article" @default.