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- W3040743806 endingPage "1845" @default.
- W3040743806 startingPage "1845" @default.
- W3040743806 abstract "In the last two decades, RNA post-transcriptional modifications, including RNA editing, have been the subject of increasing interest among the scientific community. The efforts of the Human Genome Project combined with the development of new sequencing technologies and dedicated bioinformatic approaches created to detect and profile RNA transcripts have served to further our understanding of RNA editing. Investigators have determined that non-coding RNA (ncRNA) A-to-I editing is often deregulated in cancer. This discovery has led to an increased number of published studies in the field. However, the eventual clinical application for these findings remains a work in progress. In this review, we provide an overview of the ncRNA editing phenomenon in cancer. We discuss the bioinformatic strategies for RNA editing detection as well as the potential roles for ncRNA A to I editing in tumor immunity and as clinical biomarkers." @default.
- W3040743806 created "2020-07-16" @default.
- W3040743806 creator A5001511394 @default.
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- W3040743806 creator A5053855112 @default.
- W3040743806 creator A5061759967 @default.
- W3040743806 creator A5090821383 @default.
- W3040743806 date "2020-07-08" @default.
- W3040743806 modified "2023-09-23" @default.
- W3040743806 title "Non-Coding RNA Editing in Cancer Pathogenesis" @default.
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