FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3040778914> ?p ?o ?g. }

• W3040778914 abstract "11q23/MLL rearrangements are frequently detected in pediatric acute myeloid leukemia. The analysis of their clinical significance is difficult due to the multitude of translocation fusion partners and their low frequency. The presence of t(10;11)(p12;q23) translocation was previously identified in pediatric AML. It is considered as the second most common translocation detected in pediatric 11q23/MLL-rearranged (present KMT2A) AML, after t(9;11)(p22;q23). The presence of the above translocation was previously identified as an unfavorable prognostic factor. Since June 2015 the Polish Pediatric Leukemia/Lymphoma Study Group has applied the therapeutic protocol requiring extensive diagnostics of genetic changes in pediatric AML. Until November 2019, molecular genetic studies were performed in 195 children with diagnosed AML to identify carriers of fusion gene transcripts for 28 most common chromosomal translocations in acute leukemia. The fusion gene transcript for translocation t(10;11)(p12;q23) involving MLL gene was detected with unexpectedly high frequency (8.9%) in our research. It was the highest frequency of all detected MLL rearrangements as well as other detected fusion gene transcripts from chromosomal aberrations characteristic for AML. It seems that chromosomal aberration between chromosomes 10 and 11 can be relatively frequent in some populations. Paying attention to this fact and ensuring proper genetic diagnosis seem to be important for appropriate allocation of patients to risk groups of pediatric AML treatment protocols." @default.
• W3040778914 created "2020-07-16" @default.
• W3040778914 creator A5003397043 @default.
• W3040778914 creator A5003891924 @default.
• W3040778914 creator A5004662081 @default.
• W3040778914 creator A5005488116 @default.
• W3040778914 creator A5007325086 @default.
• W3040778914 creator A5012457465 @default.
• W3040778914 creator A5018909114 @default.
• W3040778914 creator A5020450487 @default.
• W3040778914 creator A5025612296 @default.
• W3040778914 creator A5027747292 @default.
• W3040778914 creator A5028015453 @default.
• W3040778914 creator A5030714672 @default.
• W3040778914 creator A5030870747 @default.
• W3040778914 creator A5032421357 @default.
• W3040778914 creator A5032725451 @default.
• W3040778914 creator A5034539221 @default.
• W3040778914 creator A5034596046 @default.
• W3040778914 creator A5035835858 @default.
• W3040778914 creator A5036723733 @default.
• W3040778914 creator A5040158837 @default.
• W3040778914 creator A5041013402 @default.
• W3040778914 creator A5052777152 @default.
• W3040778914 creator A5057724012 @default.
• W3040778914 creator A5061002491 @default.
• W3040778914 creator A5061924630 @default.
• W3040778914 creator A5064396176 @default.
• W3040778914 creator A5064746136 @default.
• W3040778914 creator A5067782930 @default.
• W3040778914 creator A5068424348 @default.
• W3040778914 creator A5071752621 @default.
• W3040778914 creator A5072721056 @default.
• W3040778914 creator A5075544748 @default.
• W3040778914 creator A5076714732 @default.
• W3040778914 creator A5081587331 @default.
• W3040778914 date "2020-07-10" @default.
• W3040778914 modified "2023-10-18" @default.
• W3040778914 title "High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland" @default.
• W3040778914 cites W1979699800 @default.
• W3040778914 cites W1989666050 @default.
• W3040778914 cites W2000593522 @default.
• W3040778914 cites W2006940777 @default.
• W3040778914 cites W2021663709 @default.
• W3040778914 cites W2046448719 @default.
• W3040778914 cites W2048613921 @default.
• W3040778914 cites W2085092579 @default.
• W3040778914 cites W2101353517 @default.
• W3040778914 cites W2101782876 @default.
• W3040778914 cites W2141869972 @default.
• W3040778914 cites W2168891740 @default.
• W3040778914 cites W2172293555 @default.
• W3040778914 cites W2916162780 @default.
• W3040778914 doi "https://doi.org/10.3389/fped.2020.00278" @default.
• W3040778914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7366384" @default.
• W3040778914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32754558" @default.
• W3040778914 hasPublicationYear "2020" @default.
• W3040778914 type Work @default.
• W3040778914 sameAs 3040778914 @default.
• W3040778914 citedByCount "4" @default.
• W3040778914 countsByYear W30407789142021 @default.
• W3040778914 countsByYear W30407789142022 @default.
• W3040778914 crossrefType "journal-article" @default.
• W3040778914 hasAuthorship W3040778914A5003397043 @default.
• W3040778914 hasAuthorship W3040778914A5003891924 @default.
• W3040778914 hasAuthorship W3040778914A5004662081 @default.
• W3040778914 hasAuthorship W3040778914A5005488116 @default.
• W3040778914 hasAuthorship W3040778914A5007325086 @default.
• W3040778914 hasAuthorship W3040778914A5012457465 @default.
• W3040778914 hasAuthorship W3040778914A5018909114 @default.
• W3040778914 hasAuthorship W3040778914A5020450487 @default.
• W3040778914 hasAuthorship W3040778914A5025612296 @default.
• W3040778914 hasAuthorship W3040778914A5027747292 @default.
• W3040778914 hasAuthorship W3040778914A5028015453 @default.
• W3040778914 hasAuthorship W3040778914A5030714672 @default.
• W3040778914 hasAuthorship W3040778914A5030870747 @default.
• W3040778914 hasAuthorship W3040778914A5032421357 @default.
• W3040778914 hasAuthorship W3040778914A5032725451 @default.
• W3040778914 hasAuthorship W3040778914A5034539221 @default.
• W3040778914 hasAuthorship W3040778914A5034596046 @default.
• W3040778914 hasAuthorship W3040778914A5035835858 @default.
• W3040778914 hasAuthorship W3040778914A5036723733 @default.
• W3040778914 hasAuthorship W3040778914A5040158837 @default.
• W3040778914 hasAuthorship W3040778914A5041013402 @default.
• W3040778914 hasAuthorship W3040778914A5052777152 @default.
• W3040778914 hasAuthorship W3040778914A5057724012 @default.
• W3040778914 hasAuthorship W3040778914A5061002491 @default.
• W3040778914 hasAuthorship W3040778914A5061924630 @default.
• W3040778914 hasAuthorship W3040778914A5064396176 @default.
• W3040778914 hasAuthorship W3040778914A5064746136 @default.
• W3040778914 hasAuthorship W3040778914A5067782930 @default.
• W3040778914 hasAuthorship W3040778914A5068424348 @default.
• W3040778914 hasAuthorship W3040778914A5071752621 @default.
• W3040778914 hasAuthorship W3040778914A5072721056 @default.
• W3040778914 hasAuthorship W3040778914A5075544748 @default.
• W3040778914 hasAuthorship W3040778914A5076714732 @default.
• W3040778914 hasAuthorship W3040778914A5081587331 @default.
• W3040778914 hasBestOaLocation W30407789141 @default.
• W3040778914 hasConcept C104317684 @default.
• W3040778914 hasConcept C111829193 @default.

• next