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- W3040809547 abstract "Abstract The shikimate pathway is indispensable for the biosynthesis of natural products with aromatic moieties. These products have wide current and potential applications in food, cosmetics and medicine, and consequently have great commercial value. However, compounds extracted from various plants or synthesized from petrochemicals no longer satisfy the requirements of contemporary industries. As a result, an increasing number of studies has focused on this pathway to enable the biotechnological manufacture of natural products, especially in E. coli. Furthermore, the development of synthetic biology, systems metabolic engineering and high flux screening techniques has also contributed to improving the biosynthesis of high-value compounds based on the shikimate pathway. Here, we review approaches based on a combination of traditional and new metabolic engineering strategies to increase the metabolic flux of the shikimate pathway. In addition, applications of this optimized pathway to produce aromatic amino acids and a range of natural products is also elaborated. Finally, this review sums up the opportunities and challenges facing this field." @default.
- W3040809547 created "2020-07-16" @default.
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- W3040809547 date "2020-07-01" @default.
- W3040809547 modified "2023-10-13" @default.
- W3040809547 title "Metabolic engineering of <i>Escherichia coli</i> for production of chemicals derived from the shikimate pathway" @default.
- W3040809547 cites W1271249500 @default.
- W3040809547 cites W1534987347 @default.
- W3040809547 cites W1620635102 @default.
- W3040809547 cites W1966856737 @default.
- W3040809547 cites W1988927048 @default.
- W3040809547 cites W1989316655 @default.
- W3040809547 cites W1991520469 @default.
- W3040809547 cites W2006954373 @default.
- W3040809547 cites W2011072729 @default.
- W3040809547 cites W2012493190 @default.
- W3040809547 cites W2012838581 @default.
- W3040809547 cites W2014449041 @default.
- W3040809547 cites W2014831222 @default.
- W3040809547 cites W2019375008 @default.
- W3040809547 cites W2023961347 @default.
- W3040809547 cites W2028945224 @default.
- W3040809547 cites W2043419319 @default.
- W3040809547 cites W2057438618 @default.
- W3040809547 cites W2066719106 @default.
- W3040809547 cites W2072082034 @default.
- W3040809547 cites W2074125030 @default.
- W3040809547 cites W2080827205 @default.
- W3040809547 cites W2083949882 @default.
- W3040809547 cites W2091304959 @default.
- W3040809547 cites W2092828064 @default.
- W3040809547 cites W2104010980 @default.
- W3040809547 cites W2113141287 @default.
- W3040809547 cites W2113476954 @default.
- W3040809547 cites W2117912414 @default.
- W3040809547 cites W2127647479 @default.
- W3040809547 cites W2132793695 @default.
- W3040809547 cites W2141142492 @default.
- W3040809547 cites W2143511613 @default.
- W3040809547 cites W2145895228 @default.
- W3040809547 cites W2148899088 @default.
- W3040809547 cites W2149868743 @default.
- W3040809547 cites W2152277794 @default.
- W3040809547 cites W2153115688 @default.
- W3040809547 cites W2165500111 @default.
- W3040809547 cites W2187429124 @default.
- W3040809547 cites W2211752866 @default.
- W3040809547 cites W2286351261 @default.
- W3040809547 cites W2340394968 @default.
- W3040809547 cites W2401158524 @default.
- W3040809547 cites W2461609490 @default.
- W3040809547 cites W2507932427 @default.
- W3040809547 cites W2516348400 @default.
- W3040809547 cites W2551941210 @default.
- W3040809547 cites W2567602713 @default.
- W3040809547 cites W2588456700 @default.
- W3040809547 cites W259298905 @default.
- W3040809547 cites W2605447623 @default.
- W3040809547 cites W2621338227 @default.
- W3040809547 cites W2625290381 @default.
- W3040809547 cites W2692098608 @default.
- W3040809547 cites W2737950950 @default.
- W3040809547 cites W2759895308 @default.
- W3040809547 cites W2765668934 @default.
- W3040809547 cites W2767789440 @default.
- W3040809547 cites W2774577248 @default.
- W3040809547 cites W2791849537 @default.
- W3040809547 cites W2792920971 @default.
- W3040809547 cites W2797237664 @default.
- W3040809547 cites W2800771128 @default.
- W3040809547 cites W2804357581 @default.
- W3040809547 cites W2884293496 @default.
- W3040809547 cites W2884714399 @default.
- W3040809547 cites W2888985818 @default.
- W3040809547 cites W2900997616 @default.
- W3040809547 cites W2901894310 @default.
- W3040809547 cites W2915665857 @default.
- W3040809547 cites W2918961901 @default.
- W3040809547 cites W2945123466 @default.
- W3040809547 cites W3009922224 @default.
- W3040809547 doi "https://doi.org/10.1007/s10295-020-02288-2" @default.
- W3040809547 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32642925" @default.
- W3040809547 hasPublicationYear "2020" @default.
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